The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Peptidoglycan recognition protein-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 3185: Peptidoglycan recognition protein 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 24 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Peptidoglycan binding GO:0042834
Interacting selectively and non-covalently, in a non-covalent manner, with peptidoglycan, any of a class of glycoconjugates found in bacterial cell walls.
22 A1A547 (/ISS) A1A547 (/ISS) B5T255 (/ISS) C0HK98 (/ISS) O88593 (/ISS) Q0VB07 (/ISS) Q0VB07 (/ISS) Q70PY2 (/ISS) Q866Y3 (/ISS) Q8INK6 (/ISS)
(12 more)
Peptidoglycan binding GO:0042834
Interacting selectively and non-covalently, in a non-covalent manner, with peptidoglycan, any of a class of glycoconjugates found in bacterial cell walls.
11 C0HK99 (/IDA) O75594 (/IDA) Q8SXQ7 (/IDA) Q96LB8 (/IDA) Q96LB8 (/IDA) Q96LB9 (/IDA) Q96LB9 (/IDA) Q96PD5 (/IDA) Q9GNK5 (/IDA) Q9VS97 (/IDA)
(1 more)
Peptidoglycan binding GO:0042834
Interacting selectively and non-covalently, in a non-covalent manner, with peptidoglycan, any of a class of glycoconjugates found in bacterial cell walls.
11 C0HK98 (/NAS) C0HK99 (/NAS) Q70PY2 (/NAS) Q8INK6 (/NAS) Q8SXQ7 (/NAS) Q95T64 (/NAS) Q9GN97 (/NAS) Q9GNK5 (/NAS) Q9VV96 (/NAS) Q9VXN9 (/NAS)
(1 more)
N-acetylmuramoyl-L-alanine amidase activity GO:0008745
Catalysis of the hydrolysis of the link between N-acetylmuramoyl residues and L-amino acid residues in certain bacterial cell-wall glycopeptides.
8 A0A0R4IJX9 (/IDA) A5GZR3 (/IDA) C0HK99 (/IDA) F1QTZ2 (/IDA) F8W3M1 (/IDA) Q1W1Y2 (/IDA) Q70PY2 (/IDA) Q8INK6 (/IDA)
Peptidoglycan receptor activity GO:0016019
Combining with a peptidoglycan and transmitting the signal to initiate a change in cell activity.
6 O75594 (/IDA) Q96LB8 (/IDA) Q96LB8 (/IDA) Q96LB9 (/IDA) Q96LB9 (/IDA) Q96PD5 (/IDA)
Peptidoglycan receptor activity GO:0016019
Combining with a peptidoglycan and transmitting the signal to initiate a change in cell activity.
6 A1A547 (/ISO) A1A547 (/ISO) O88593 (/ISO) Q0VB07 (/ISO) Q0VB07 (/ISO) Q8VCS0 (/ISO)
Peptidoglycan binding GO:0042834
Interacting selectively and non-covalently, in a non-covalent manner, with peptidoglycan, any of a class of glycoconjugates found in bacterial cell walls.
6 A1A547 (/ISO) A1A547 (/ISO) O88593 (/ISO) Q0VB07 (/ISO) Q0VB07 (/ISO) Q8VCS0 (/ISO)
N-acetylmuramoyl-L-alanine amidase activity GO:0008745
Catalysis of the hydrolysis of the link between N-acetylmuramoyl residues and L-amino acid residues in certain bacterial cell-wall glycopeptides.
5 C0HK98 (/ISS) Q70PY2 (/ISS) Q8INK6 (/ISS) Q9V4X2 (/ISS) Q9VV96 (/ISS)
Peptidoglycan binding GO:0042834
Interacting selectively and non-covalently, in a non-covalent manner, with peptidoglycan, any of a class of glycoconjugates found in bacterial cell walls.
5 C0HK99 (/TAS) Q8INK6 (/TAS) Q9GNK5 (/TAS) Q9VXN9 (/TAS) Q9VYX7 (/TAS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
4 Q8INK6 (/IPI) Q9GNK5 (/IPI) Q9VXN9 (/IPI) Q9VYX7 (/IPI)
Peptidoglycan receptor activity GO:0016019
Combining with a peptidoglycan and transmitting the signal to initiate a change in cell activity.
4 Q866Y3 (/ISS) Q8VCS0 (/ISS) Q9VXN9 (/ISS) Q9VYX7 (/ISS)
Peptidoglycan receptor activity GO:0016019
Combining with a peptidoglycan and transmitting the signal to initiate a change in cell activity.
4 Q9GNK5 (/TAS) Q9JLN4 (/TAS) Q9VXN9 (/TAS) Q9VYX7 (/TAS)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
4 Q96LB8 (/IPI) Q96LB8 (/IPI) Q96LB9 (/IPI) Q96LB9 (/IPI)
Peptidoglycan receptor activity GO:0016019
Combining with a peptidoglycan and transmitting the signal to initiate a change in cell activity.
3 Q9GNK5 (/NAS) Q9VXN9 (/NAS) Q9VYX7 (/NAS)
Signaling pattern recognition receptor activity GO:0008329
Combining with a pathogen-associated molecular pattern (PAMP), a structure conserved among microbial species, or damage-associated molecular pattern (DAMP), an endogenous molecule released from damaged cells), and transmitting a signal to initiate a change in cell activity.
2 Q9GNK5 (/TAS) Q9VYX7 (/TAS)
Lipopolysaccharide receptor activity GO:0001875
Combining with a lipopolysaccharide and transmitting the signal across the cell membrane to initiate a change in cell activity. Lipopolysaccharides (LPS) are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system.
1 Q9GNK5 (/IMP)
Amidase activity GO:0004040
Catalysis of the reaction: a monocarboxylic acid amide + H2O = a monocarboxylate + NH3.
1 Q8INK6 (/NAS)
N-acetylmuramoyl-L-alanine amidase activity GO:0008745
Catalysis of the hydrolysis of the link between N-acetylmuramoyl residues and L-amino acid residues in certain bacterial cell-wall glycopeptides.
1 Q96PD5 (/EXP)
N-acetylmuramoyl-L-alanine amidase activity GO:0008745
Catalysis of the hydrolysis of the link between N-acetylmuramoyl residues and L-amino acid residues in certain bacterial cell-wall glycopeptides.
1 Q8VCS0 (/ISO)
N-acetylmuramoyl-L-alanine amidase activity GO:0008745
Catalysis of the hydrolysis of the link between N-acetylmuramoyl residues and L-amino acid residues in certain bacterial cell-wall glycopeptides.
1 Q96PD5 (/TAS)
Peptidoglycan receptor activity GO:0016019
Combining with a peptidoglycan and transmitting the signal to initiate a change in cell activity.
1 Q9GNK5 (/IMP)
Muramyl dipeptide binding GO:0032500
Interacting selectively and non-covalently, in a non-covalent manner, with muramyl dipeptide; muramyl dipeptide is derived from peptidoglycan.
1 Q9VYX7 (/IDA)
Protein dimerization activity GO:0046983
The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.
1 Q9GNK5 (/IDA)
Protein dimerization activity GO:0046983
The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.
1 Q9GNK5 (/NAS)

There are 71 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Innate immune response GO:0045087
Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.
17 C0HK98 (/NAS) C0HK99 (/NAS) O75594 (/NAS) Q70PY2 (/NAS) Q8INK6 (/NAS) Q95T64 (/NAS) Q96LB8 (/NAS) Q96LB8 (/NAS) Q96LB9 (/NAS) Q96LB9 (/NAS)
(7 more)
Immune response GO:0006955
Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
10 C0HK98 (/ISS) Q70PY2 (/ISS) Q8INK6 (/ISS) Q95T64 (/ISS) Q9GN97 (/ISS) Q9GNK5 (/ISS) Q9V4X2 (/ISS) Q9VV96 (/ISS) Q9VXN9 (/ISS) Q9VYX7 (/ISS)
Peptidoglycan catabolic process GO:0009253
The chemical reactions and pathways resulting in the breakdown of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls.
10 C0HK98 (/NAS) C0HK99 (/NAS) Q70PY2 (/NAS) Q8INK6 (/NAS) Q8SXQ7 (/NAS) Q95T64 (/NAS) Q9GN97 (/NAS) Q9VV96 (/NAS) Q9VXN9 (/NAS) Q9VYX7 (/NAS)
Defense response to Gram-positive bacterium GO:0050830
Reactions triggered in response to the presence of a Gram-positive bacterium that act to protect the cell or organism.
10 O75594 (/IDA) Q8INK6 (/IDA) Q96LB8 (/IDA) Q96LB8 (/IDA) Q96LB9 (/IDA) Q96LB9 (/IDA) Q96PD5 (/IDA) Q9VS97 (/IDA) Q9VXN9 (/IDA) Q9VYX7 (/IDA)
Detection of bacterium GO:0016045
The series of events in which a stimulus from a bacterium is received and converted into a molecular signal.
6 O75594 (/IDA) Q96LB8 (/IDA) Q96LB8 (/IDA) Q96LB9 (/IDA) Q96LB9 (/IDA) Q96PD5 (/IDA)
Detection of bacterium GO:0016045
The series of events in which a stimulus from a bacterium is received and converted into a molecular signal.
6 A1A547 (/ISO) A1A547 (/ISO) O88593 (/ISO) Q0VB07 (/ISO) Q0VB07 (/ISO) Q8VCS0 (/ISO)
Negative regulation of interferon-gamma production GO:0032689
Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.
6 A1A547 (/IMP) A1A547 (/IMP) O88593 (/IMP) Q0VB07 (/IMP) Q0VB07 (/IMP) Q8VCS0 (/IMP)
Negative regulation of natural killer cell differentiation involved in immune response GO:0032827
Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell differentiation as part of an immune response.
6 A1A547 (/IMP) A1A547 (/IMP) O88593 (/IMP) Q0VB07 (/IMP) Q0VB07 (/IMP) Q8VCS0 (/IMP)
Growth of symbiont in host GO:0044117
The increase in size or mass of an organism, occurring within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down host tissue. The host is defined as the larger of the organisms involved in a symbiotic interaction.
6 A1A547 (/IMP) A1A547 (/IMP) O88593 (/IMP) Q0VB07 (/IMP) Q0VB07 (/IMP) Q8VCS0 (/IMP)
Defense response to Gram-positive bacterium GO:0050830
Reactions triggered in response to the presence of a Gram-positive bacterium that act to protect the cell or organism.
6 A1A547 (/ISO) A1A547 (/ISO) O88593 (/ISO) Q0VB07 (/ISO) Q0VB07 (/ISO) Q8VCS0 (/ISO)
Peptidoglycan catabolic process GO:0009253
The chemical reactions and pathways resulting in the breakdown of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls.
5 C0HK98 (/ISS) Q70PY2 (/ISS) Q8INK6 (/ISS) Q9V4X2 (/ISS) Q9VV96 (/ISS)
Killing of cells of other organism GO:0031640
Any process in an organism that results in the killing of cells of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions.
5 O75594 (/IDA) Q96LB8 (/IDA) Q96LB8 (/IDA) Q96LB9 (/IDA) Q96LB9 (/IDA)
Defense response to bacterium GO:0042742
Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
5 A0A0R4IJX9 (/IDA) A5GZR3 (/IDA) F1QTZ2 (/IDA) F8W3M1 (/IDA) Q1W1Y2 (/IDA)
Positive regulation of cytolysis in other organism GO:0051714
Any process that activates or increases the frequency, rate or extent of the cytolysis by an organism of cells in another organism.
5 O75594 (/IDA) Q96LB8 (/IDA) Q96LB8 (/IDA) Q96LB9 (/IDA) Q96LB9 (/IDA)
Antimicrobial humoral immune response mediated by antimicrobial peptide GO:0061844
An immune response against microbes mediated by anti-microbial peptides in body fluid.
5 O75594 (/IDA) Q96LB8 (/IDA) Q96LB8 (/IDA) Q96LB9 (/IDA) Q96LB9 (/IDA)
Immune response GO:0006955
Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
4 O75594 (/TAS) Q9JLN4 (/TAS) Q9VXN9 (/TAS) Q9VYX7 (/TAS)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
4 A0A060VTM4 (/IMP) A0A060Y1K9 (/IMP) M9PNP3 (/IMP) M9PNV5 (/IMP)
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
4 A0A060VTM4 (/IMP) A0A060Y1K9 (/IMP) M9PNP3 (/IMP) M9PNV5 (/IMP)
Antimicrobial humoral response GO:0019730
An immune response against microbes mediated through a body fluid. Examples of this process are seen in the antimicrobial humoral response of Drosophila melanogaster and Mus musculus.
4 O75594 (/TAS) Q96LB9 (/TAS) Q96LB9 (/TAS) Q96PD5 (/TAS)
Defense response to bacterium GO:0042742
Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
4 A0A0R4IJX9 (/IMP) F1QTZ2 (/IMP) Q1W1Y2 (/IMP) Q9VXN9 (/IMP)
Negative regulation of nucleotide-binding oligomerization domain containing signaling pathway GO:0070425
Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing (NOD) pathway.
4 A0A060VTM4 (/IMP) A0A060Y1K9 (/IMP) M9PNP3 (/IMP) M9PNV5 (/IMP)
Negative regulation of cytokine production involved in inflammatory response GO:1900016
Any process that stops, prevents or reduces the frequency, rate or extent of cytokine production involved in inflammatory response.
4 A0A060VTM4 (/IMP) A0A060Y1K9 (/IMP) M9PNP3 (/IMP) M9PNV5 (/IMP)
Negative regulation of intracellular signal transduction GO:1902532
Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction.
4 A0A060VTM4 (/IMP) A0A060Y1K9 (/IMP) M9PNP3 (/IMP) M9PNV5 (/IMP)
Innate immune response GO:0045087
Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.
3 C0HK99 (/TAS) Q9GNK5 (/TAS) Q9VYX7 (/TAS)
Defense response to Gram-positive bacterium GO:0050830
Reactions triggered in response to the presence of a Gram-positive bacterium that act to protect the cell or organism.
3 Q70PR8 (/ISS) Q866Y3 (/ISS) Q8VCS0 (/ISS)
Determination of adult lifespan GO:0008340
The control of viability and duration in the adult phase of the life-cycle.
2 Q8SXQ7 (/IMP) Q9VXN9 (/IMP)
Response to bacterium GO:0009617
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.
2 Q8SXQ7 (/IDA) Q95T64 (/IDA)
Detection of bacterium GO:0016045
The series of events in which a stimulus from a bacterium is received and converted into a molecular signal.
2 Q866Y3 (/ISS) Q8VCS0 (/ISS)
Antibacterial humoral response GO:0019731
An immune response against bacteria mediated through a body fluid. Examples of this process are the antibacterial humoral responses in Mus musculus and Drosophila melanogaster.
2 Q8SXQ7 (/IMP) Q9GNK5 (/IMP)
Negative regulation of innate immune response GO:0045824
Any process that stops, prevents, or reduces the frequency, rate or extent of the innate immune response.
2 C0HK98 (/IDA) Q9V4X2 (/IDA)
Defense response to Gram-negative bacterium GO:0050829
Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.
2 Q9GNK5 (/IMP) Q9VS97 (/IMP)
Peptidoglycan recognition protein signaling pathway GO:0061057
A series of molecular signals initiated by binding of peptidoglycan to a receptor on the surface of the target cell and ending with regulation of a downstream cellular process. The main outcome of the Imd signaling is the production of antimicrobial peptides.
2 Q9GNK5 (/IDA) Q9VXN9 (/IDA)
Peptidoglycan recognition protein signaling pathway GO:0061057
A series of molecular signals initiated by binding of peptidoglycan to a receptor on the surface of the target cell and ending with regulation of a downstream cellular process. The main outcome of the Imd signaling is the production of antimicrobial peptides.
2 Q8SXQ7 (/IMP) Q9GNK5 (/IMP)
Positive regulation of peptidoglycan recognition protein signaling pathway GO:0061059
Any process that increases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway.
2 Q9GNK5 (/IGI) Q9VS97 (/IGI)
Peptidoglycan metabolic process GO:0000270
The chemical reactions and pathways involving peptidoglycans, any of a class of glycoconjugates found only in bacterial cell walls and consisting of strands of glycosaminoglycan cross-linked by oligopeptides to form a huge and rigid network.
1 Q8INK6 (/NAS)
Peptide amidation GO:0001519
The posttranslational conversion of C-terminal glycine-extended peptides to C-terminal alpha-amidated peptides. Occurs to over half of all peptide hormones to give bioactive peptides. This is a two step process catalyzed by a peptidyl-glycine alpha-hydroxylating monooxygenase and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase. In some organisms, this process is catalyzed by two separate enzymes, whereas in higher organisms, one polypeptide catalyzes both reactions.
1 Q96PD5 (/NAS)
Negative regulation of cytokine production GO:0001818
Any process that stops, prevents, or reduces the rate of production of a cytokine.
1 Q9GK12 (/IDA)
Regulation of humoral immune response GO:0002920
Any process that modulates the frequency, rate, or extent of a humoral immune response.
1 Q9GNK5 (/IMP)
Phagocytosis GO:0006909
An endocytosis process that results in the engulfment of external particulate material by phagocytes. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles.
1 Q9GNK5 (/TAS)
Immune response GO:0006955
Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
1 Q9GNK5 (/IMP)
Positive regulation of antibacterial peptide biosynthetic process GO:0006963
Any process that activates or increases the frequency, rate, or extent of antibacterial peptide biosynthesis.
1 Q9GNK5 (/IMP)
Positive regulation of antibacterial peptide biosynthetic process GO:0006963
Any process that activates or increases the frequency, rate, or extent of antibacterial peptide biosynthesis.
1 Q9GNK5 (/TAS)
Positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria GO:0006964
Any process that activates or increases the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-negative bacteria.
1 Q9GNK5 (/IMP)
Positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria GO:0006965
Any process that activates or increases the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-positive bacteria.
1 Q9VYX7 (/IMP)
Positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria GO:0006965
Any process that activates or increases the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-positive bacteria.
1 Q9VYX7 (/TAS)
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
1 Q9VXN9 (/TAS)
Toll signaling pathway GO:0008063
A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Toll on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
1 Q9VYX7 (/TAS)
Regulation of Toll signaling pathway GO:0008592
Any process that modulates the frequency, rate or extent of the Tl signaling pathway.
1 Q9VYX7 (/TAS)
Peptidoglycan catabolic process GO:0009253
The chemical reactions and pathways resulting in the breakdown of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls.
1 C0HK99 (/IDA)
Response to bacterium GO:0009617
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.
1 Q9GNK5 (/IMP)
Antimicrobial humoral response GO:0019730
An immune response against microbes mediated through a body fluid. Examples of this process are seen in the antimicrobial humoral response of Drosophila melanogaster and Mus musculus.
1 Q9GNK5 (/IMP)
Response to peptidoglycan GO:0032494
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptidoglycan stimulus. Peptidoglycan is a bacterial cell wall macromolecule.
1 Q9VYX7 (/IMP)
Detection of peptidoglycan GO:0032499
The series of events in which a peptidoglycan stimulus is received by a cell and converted into a molecular signal. Peptidoglycan is a bacterial cell wall macromolecule.
1 Q9VS97 (/IMP)
Regulation of melanization defense response GO:0035007
Any process that affects the rate, extent or location of the melanization defense response during injury or invasion.
1 Q9GNK5 (/IMP)
Neutrophil degranulation GO:0043312
The regulated exocytosis of secretory granules containing preformed mediators such as proteases, lipases, and inflammatory mediators by a neutrophil.
1 O75594 (/TAS)
Positive regulation of innate immune response GO:0045089
Any process that activates or increases the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.
1 Q9VXN9 (/IMP)
Regulation of circadian sleep/wake cycle, sleep GO:0045187
Any process that modulates the frequency, rate or extent of sleep; a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals.
1 Q9JLN4 (/IEP)
Negative regulation of JNK cascade GO:0046329
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the JNK cascade.
1 Q8SXQ7 (/IGI)
Regulation of synaptic plasticity GO:0048167
A process that modulates synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.
1 Q9GNK5 (/IMP)
Regulation of inflammatory response GO:0050727
Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents.
1 Q8VCS0 (/IMP)
Negative regulation of inflammatory response GO:0050728
Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response.
1 O88593 (/IMP)
Defense response to Gram-negative bacterium GO:0050829
Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.
1 Q9GNK5 (/IDA)
Defense response to Gram-negative bacterium GO:0050829
Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.
1 Q9GNK5 (/TAS)
Defense response to Gram-positive bacterium GO:0050830
Reactions triggered in response to the presence of a Gram-positive bacterium that act to protect the cell or organism.
1 Q9VYX7 (/IGI)
Defense response to Gram-positive bacterium GO:0050830
Reactions triggered in response to the presence of a Gram-positive bacterium that act to protect the cell or organism.
1 Q9VS97 (/IMP)
Defense response to Gram-positive bacterium GO:0050830
Reactions triggered in response to the presence of a Gram-positive bacterium that act to protect the cell or organism.
1 Q9VYX7 (/TAS)
Defense response to virus GO:0051607
Reactions triggered in response to the presence of a virus that act to protect the cell or organism.
1 Q9GNK5 (/IMP)
Peptidoglycan recognition protein signaling pathway GO:0061057
A series of molecular signals initiated by binding of peptidoglycan to a receptor on the surface of the target cell and ending with regulation of a downstream cellular process. The main outcome of the Imd signaling is the production of antimicrobial peptides.
1 Q9GNK5 (/IGI)
Positive regulation of peptidoglycan recognition protein signaling pathway GO:0061059
Any process that increases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway.
1 Q9VS97 (/IMP)
Negative regulation of peptidoglycan recognition protein signaling pathway GO:0061060
Any process that decreases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway.
1 Q8INK6 (/IDA)
Defense response to other organism GO:0098542
Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism.
1 Q8SXQ7 (/IMP)

There are 23 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
8 C0HK98 (/ISS) C0HK99 (/ISS) Q70PR8 (/ISS) Q70PW6 (/ISS) Q70PY2 (/ISS) Q9V4X2 (/ISS) Q9VV96 (/ISS) Q9VYX7 (/ISS)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
6 Q70PY2 (/IDA) Q8INK6 (/IDA) Q9VS97 (/IDA) Q9VV96 (/IDA) Q9VXN9 (/IDA) Q9VYX7 (/IDA)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
5 A0A060VTM4 (/IDA) A0A060Y1K9 (/IDA) M9PNP3 (/IDA) M9PNV5 (/IDA) Q9VS97 (/IDA)
Intracellular GO:0005622
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
5 Q96LB8 (/NAS) Q96LB8 (/NAS) Q96LB9 (/NAS) Q96LB9 (/NAS) Q96PD5 (/NAS)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
5 Q96LB8 (/NAS) Q96LB8 (/NAS) Q96LB9 (/NAS) Q96LB9 (/NAS) Q96PD5 (/NAS)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
4 C0HK98 (/NAS) C0HK99 (/NAS) O75594 (/NAS) Q9VXN9 (/NAS)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
4 O75594 (/TAS) Q96LB9 (/TAS) Q96LB9 (/TAS) Q96PD5 (/TAS)
Protein complex GO:0043234
A stable macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.
4 Q96LB8 (/IDA) Q96LB8 (/IDA) Q96LB9 (/IDA) Q96LB9 (/IDA)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
3 Q8SXQ7 (/NAS) Q95T64 (/NAS) Q9GN97 (/NAS)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
3 Q95T64 (/ISS) Q9GN97 (/ISS) Q9GNK5 (/ISS)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 Q8SXQ7 (/IDA) Q9GNK5 (/IDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
2 O75594 (/IDA) Q96PD5 (/IDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
2 O88593 (/ISO) Q8VCS0 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q9GNK5 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q9GNK5 (/IDA)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q9GNK5 (/NAS)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q9GNK5 (/TAS)
Apicolateral plasma membrane GO:0016327
The apical end of the lateral plasma membrane of epithelial cells.
1 Q9GNK5 (/IDA)
Specific granule lumen GO:0035580
The volume enclosed by the membrane of a specific granule, a granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase.
1 O75594 (/TAS)
Spanning component of plasma membrane GO:0044214
The component of the plasma membrane consisting of gene products and protein complexes that have some part that spans both leaflets of the membrane.
1 Q9GNK5 (/ISM)
Phagocytic vesicle lumen GO:0097013
The volume enclosed by the membrane of a phagocytic vesicle.
1 O75594 (/TAS)
Presynapse GO:0098793
The part of a synapse that is part of the presynaptic cell.
1 Q9GNK5 (/IDA)
Tertiary granule lumen GO:1904724
Any membrane-enclosed lumen that is part of a tertiary granule.
1 O75594 (/TAS)
CATH-Gene3D is a Global Biodata Core Resource Learn more...