The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Peptidoglycan recognition protein-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 3185: Peptidoglycan recognition protein 1

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
N-acetylmuramoyl-L-alanine amidase. [EC: 3.5.1.28]
Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides.
  • Formerly EC 3.4.12.5, EC 3.4.17.7 and EC 3.4.19.10.
147 A0A061HY63 A0A061IM12 A0A061IM12 A0A061IPU2 A0A061IPU2 A0A061IQK2 A0A061IQK2 A0A061IR86 A0A061IR86 A0A075FET3
(137 more...)
Muramoyltetrapeptide carboxypeptidase. [EC: 3.4.17.13]
GlcNAc-MurNAc-L-alanyl-gamma-D-glutamyl-meso-diaminopimelyl-D-alanine + H(2)O = GlcNAc-MurNAc-L-alanyl-gamma-D-glutamyl-meso-diaminopimelate + D-alanine.
  • Variants are known from various microorganisms.
  • Involved in peptidoglycan synthesis, catalyzing both decarboxylation and transpeptidation.
  • Stimulated by divalent cations such as magnesium and calcium, but not zinc.
  • Inhibited by thiol-blocking reagents, but unaffected by penicillin.
4 E0W210 E0W210 Q9VYX7 X2JEI8
Amidase. [EC: 3.5.1.4]
A monocarboxylic acid amide + H(2)O = a monocarboxylate + NH(3).
    1 A0A0B4K741
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