The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 291477: Pentafunctional AROM polypeptide 2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 13 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Shikimate 3-dehydrogenase (NADP+) activity GO:0004764
Catalysis of the reaction: shikimate + NADP+ = 3-dehydroshikimate + NADPH + H+.
2 P08566 (/IDA) P25415 (/IDA)
3-dehydroquinate dehydratase activity GO:0003855
Catalysis of the reaction: 3-dehydroquinate = 3-dehydroshikimate + H(2)O.
1 P08566 (/IDA)
3-dehydroquinate dehydratase activity GO:0003855
Catalysis of the reaction: 3-dehydroquinate = 3-dehydroshikimate + H(2)O.
1 Q5AS44 (/RCA)
3-dehydroquinate synthase activity GO:0003856
Catalysis of the reaction: 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate = 3-dehydroquinate + phosphate.
1 P08566 (/IDA)
3-dehydroquinate synthase activity GO:0003856
Catalysis of the reaction: 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate = 3-dehydroquinate + phosphate.
1 Q5AS44 (/RCA)
3-phosphoshikimate 1-carboxyvinyltransferase activity GO:0003866
Catalysis of the reaction: 3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphate.
1 P08566 (/IDA)
3-phosphoshikimate 1-carboxyvinyltransferase activity GO:0003866
Catalysis of the reaction: 3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphate.
1 Q5AS44 (/RCA)
Shikimate 3-dehydrogenase (NADP+) activity GO:0004764
Catalysis of the reaction: shikimate + NADP+ = 3-dehydroshikimate + NADPH + H+.
1 Q5AS44 (/RCA)
Shikimate kinase activity GO:0004765
Catalysis of the reaction: ATP + shikimate = 3-phosphoshikimate + ADP + 2 H(+).
1 P08566 (/IDA)
Shikimate kinase activity GO:0004765
Catalysis of the reaction: ATP + shikimate = 3-phosphoshikimate + ADP + 2 H(+).
1 Q5AS44 (/RCA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 P08566 (/IPI)
Quinate 3-dehydrogenase (NAD+) activity GO:0030266
Catalysis of the reaction: (-)-quinate + NAD+ = (-)-3-dehydroquinate + NADH + H+.
1 P25415 (/IDA)
Quinate 3-dehydrogenase (NAD+) activity GO:0030266
Catalysis of the reaction: (-)-quinate + NAD+ = (-)-3-dehydroquinate + NADH + H+.
1 P25415 (/RCA)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Aromatic amino acid family biosynthetic process GO:0009073
The chemical reactions and pathways resulting in the formation of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).
2 P25415 (/RCA) Q5AS44 (/RCA)
Quinate catabolic process GO:0019631
The chemical reactions and pathways resulting in the breakdown of quinate, the anion of quinic acid.
2 P25415 (/IMP) Q00784 (/IMP)
Negative regulation of transcription from RNA polymerase II promoter GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 Q00784 (/IMP)
Chorismate biosynthetic process GO:0009423
The chemical reactions and pathways resulting in the formation of the unsymmetrical ether derived from phosphoenolpyruvate and 5-phosphoshikimic acid formed as an intermediate in the biosynthesis of aromatic amino acids and many other compounds.
1 Q9P7R0 (/ISO)
Chorismate biosynthetic process GO:0009423
The chemical reactions and pathways resulting in the formation of the unsymmetrical ether derived from phosphoenolpyruvate and 5-phosphoshikimic acid formed as an intermediate in the biosynthesis of aromatic amino acids and many other compounds.
1 P08566 (/TAS)
Quinate catabolic process GO:0019631
The chemical reactions and pathways resulting in the breakdown of quinate, the anion of quinic acid.
1 P25415 (/IDA)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q9P7R0 (/IDA)