The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Glycogen Phosphorylase B;
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 97281: Alpha-1,4 glucan phosphorylase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 29 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Glycogen phosphorylase activity GO:0008184
Catalysis of the reaction: glycogen + phosphate = maltodextrin + alpha-D-glucose 1-phosphate.
11 P06737 (/IDA) P06738 (/IDA) P09811 (/IDA) P09812 (/IDA) P0AC86 (/IDA) P34114 (/IDA) P53534 (/IDA) Q00766 (/IDA) Q9ET01 (/IDA) Q9WUB3 (/IDA)
(1 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
5 P06737 (/IPI) P06738 (/IPI) P11216 (/IPI) P11217 (/IPI) Q9ET01 (/IPI)
Glycogen phosphorylase activity GO:0008184
Catalysis of the reaction: glycogen + phosphate = maltodextrin + alpha-D-glucose 1-phosphate.
5 P06737 (/IMP) P06738 (/IMP) P09811 (/IMP) Q9WUB3 (/IMP) Q9XTL9 (/IMP)
Drug binding GO:0008144
Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
4 P06737 (/IDA) P09811 (/IDA) P09812 (/IDA) P53534 (/IDA)
Glycogen phosphorylase activity GO:0008184
Catalysis of the reaction: glycogen + phosphate = maltodextrin + alpha-D-glucose 1-phosphate.
4 Q604J9 (/ISS) Q60CN8 (/ISS) Q74BH5 (/ISS) Q81K86 (/ISS)
Pyridoxal phosphate binding GO:0030170
Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.
4 P00490 (/IDA) P09812 (/IDA) P0AC86 (/IDA) Q9XTL9 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
4 P09811 (/IDA) P34114 (/IDA) P53534 (/IDA) Q9XTL9 (/IDA)
Glycogen phosphorylase activity GO:0008184
Catalysis of the reaction: glycogen + phosphate = maltodextrin + alpha-D-glucose 1-phosphate.
3 P09812 (/TAS) P11217 (/TAS) P53534 (/TAS)
Carbohydrate binding GO:0030246
Interacting selectively and non-covalently with any carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates.
3 P09811 (/IDA) P09812 (/IDA) P53534 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
3 P09811 (/IC) P09812 (/IC) P53534 (/IC)
Phosphorylase activity GO:0004645
Catalysis of the reaction: 1,4-alpha-D-glucosyl(n) + phosphate = 1,4-alpha-D-glucosyl(n-1) + alpha-D-glucose 1-phosphate. The name should be qualified in each instance by adding the name of the natural substrate, e.g. maltodextrin phosphorylase, starch phosphorylase, glycogen phosphorylase.
2 Q8EGU5 (/ISS) Q9KNF1 (/ISS)
Glycogen phosphorylase activity GO:0008184
Catalysis of the reaction: glycogen + phosphate = maltodextrin + alpha-D-glucose 1-phosphate.
2 A0A1D8PQQ3 (/NAS) P11216 (/NAS)
AMP binding GO:0016208
Interacting selectively and non-covalently with AMP, adenosine monophosphate.
2 P06737 (/IDA) P09812 (/IDA)
Purine nucleobase binding GO:0002060
Interacting selectively and non-covalently with a purine nucleobase, an organic nitrogenous base with a purine skeleton.
1 P06737 (/IDA)
Purine nucleobase binding GO:0002060
Interacting selectively and non-covalently with a purine nucleobase, an organic nitrogenous base with a purine skeleton.
1 Q9ET01 (/ISO)
Phosphorylase activity GO:0004645
Catalysis of the reaction: 1,4-alpha-D-glucosyl(n) + phosphate = 1,4-alpha-D-glucosyl(n-1) + alpha-D-glucose 1-phosphate. The name should be qualified in each instance by adding the name of the natural substrate, e.g. maltodextrin phosphorylase, starch phosphorylase, glycogen phosphorylase.
1 C8VU49 (/RCA)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
1 P06737 (/IDA)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
1 Q9ET01 (/ISO)
Glucose binding GO:0005536
Interacting selectively and non-covalently with the D- or L-enantiomer of glucose.
1 P06737 (/NAS)
Drug binding GO:0008144
Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
1 Q9ET01 (/ISO)
Glycogen phosphorylase activity GO:0008184
Catalysis of the reaction: glycogen + phosphate = maltodextrin + alpha-D-glucose 1-phosphate.
1 P06737 (/EXP)
Glycogen phosphorylase activity GO:0008184
Catalysis of the reaction: glycogen + phosphate = maltodextrin + alpha-D-glucose 1-phosphate.
1 Q9ET01 (/ISO)
AMP binding GO:0016208
Interacting selectively and non-covalently with AMP, adenosine monophosphate.
1 Q9ET01 (/ISO)
Vitamin binding GO:0019842
Interacting selectively and non-covalently with a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.
1 P06737 (/IDA)
Vitamin binding GO:0019842
Interacting selectively and non-covalently with a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.
1 Q9ET01 (/ISO)
Maltodextrin phosphorylase activity GO:0031220
Catalysis of the reaction: maltodextrin = glucose-1-phosphate.
1 P00490 (/IDA)
Bile acid binding GO:0032052
Interacting selectively and non-covalently with bile acids, any of a group of steroid carboxylic acids occurring in bile.
1 P06737 (/IDA)
Bile acid binding GO:0032052
Interacting selectively and non-covalently with bile acids, any of a group of steroid carboxylic acids occurring in bile.
1 Q9ET01 (/ISO)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 P06737 (/NAS)

There are 30 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Glycogen catabolic process GO:0005980
The chemical reactions and pathways resulting in the breakdown of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues.
7 P00490 (/IDA) P09811 (/IDA) P09812 (/IDA) P34114 (/IDA) P53534 (/IDA) Q00766 (/IDA) Q9WUB3 (/IDA)
Glycogen metabolic process GO:0005977
The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages.
4 P09811 (/IDA) P09812 (/IDA) P53534 (/IDA) Q9ET01 (/IDA)
Glycogen catabolic process GO:0005980
The chemical reactions and pathways resulting in the breakdown of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues.
4 P06738 (/IMP) P0AC86 (/IMP) Q9WUB3 (/IMP) Q9XTL9 (/IMP)
Carbohydrate metabolic process GO:0005975
The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule.
3 Q81K86 (/ISS) Q8EGU5 (/ISS) Q9KNF1 (/ISS)
Glycogen catabolic process GO:0005980
The chemical reactions and pathways resulting in the breakdown of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues.
3 Q604J9 (/ISS) Q60CN8 (/ISS) Q74BH5 (/ISS)
Response to cAMP GO:0051591
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus.
3 P09812 (/IDA) P34114 (/IDA) Q00766 (/IDA)
Glycogen catabolic process GO:0005980
The chemical reactions and pathways resulting in the breakdown of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues.
2 P06737 (/TAS) P11217 (/TAS)
Neutrophil degranulation GO:0043312
The regulated exocytosis of secretory granules containing preformed mediators such as proteases, lipases, and inflammatory mediators by a neutrophil.
2 P06737 (/TAS) P11216 (/TAS)
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
1 P09812 (/IDA)
Glycogen metabolic process GO:0005977
The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages.
1 P06737 (/IMP)
Glycogen metabolic process GO:0005977
The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages.
1 Q9ET01 (/ISO)
Glycogen metabolic process GO:0005977
The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages.
1 P11217 (/TAS)
Glycogen catabolic process GO:0005980
The chemical reactions and pathways resulting in the breakdown of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues.
1 P11216 (/NAS)
Glycogen catabolic process GO:0005980
The chemical reactions and pathways resulting in the breakdown of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues.
1 C8VU49 (/RCA)
5-phosphoribose 1-diphosphate biosynthetic process GO:0006015
The chemical reactions and pathways resulting in the formation of 5-phosphoribose 1-diphosphate, also known as 5-phosphoribosyl-1-pyrophosphate.
1 P09811 (/IMP)
Cellular calcium ion homeostasis GO:0006874
Any process involved in the maintenance of an internal steady state of calcium ions at the level of a cell.
1 P09812 (/IDA)
Determination of adult lifespan GO:0008340
The control of viability and duration in the adult phase of the life-cycle.
1 Q9XTL9 (/IMP)
Response to organic substance GO:0010033
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.
1 P09812 (/IDA)
Carbohydrate catabolic process GO:0016052
The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
1 P0AC86 (/IDA)
Alpha-glucan catabolic process GO:0030980
The chemical reactions and pathways resulting in the breakdown of alpha-glucans.
1 P00490 (/IDA)
Alpha-glucan catabolic process GO:0030980
The chemical reactions and pathways resulting in the breakdown of alpha-glucans.
1 P00490 (/IMP)
Glucose homeostasis GO:0042593
Any process involved in the maintenance of an internal steady state of glucose within an organism or cell.
1 P06737 (/IMP)
Glucose homeostasis GO:0042593
Any process involved in the maintenance of an internal steady state of glucose within an organism or cell.
1 Q9ET01 (/ISO)
Positive regulation of glycogen catabolic process GO:0045819
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen.
1 Q9XTL9 (/IMP)
Negative regulation of innate immune response GO:0045824
Any process that stops, prevents, or reduces the frequency, rate or extent of the innate immune response.
1 Q9XTL9 (/IMP)
Defense response to Gram-negative bacterium GO:0050829
Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.
1 Q9XTL9 (/IMP)
Flight GO:0060361
Self-propelled movement of an organism from one location to another through the air, usually by means of active wing movement.
1 Q9XTL9 (/IMP)
Necroptotic process GO:0070266
A programmed necrotic cell death process which begins when a cell receives a signal (e.g. a ligand binding to a death receptor or to a Toll-like receptor), and proceeds through a series of biochemical events (signaling pathways), characterized by activation of receptor-interacting serine/threonine-protein kinase 1 and/or 3 (RIPK1/3, also called RIP1/3) and by critical dependence on mixed lineage kinase domain-like (MLKL), and which typically lead to common morphological features of necrotic cell death. The process ends when the cell has died. The process is divided into a signaling phase, and an execution phase, which is triggered by the former.
1 Q9ET01 (/IGI)
Response to 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one GO:1903013
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one stimulus.
1 P34114 (/IDA)
Response to ammonia GO:1903717
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonia stimulus.
1 P34114 (/IDA)

There are 27 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cell GO:0005623
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
13 A0A091EVW2 (/ISS) A0A091GTE7 (/ISS) A0A091HP59 (/ISS) A0A091K3J9 (/ISS) A0A091RXH8 (/ISS) A0A091XPS4 (/ISS) A0A093IMK0 (/ISS) A0A093PK98 (/ISS) A0A099ZA67 (/ISS) R0LE95 (/ISS)
(3 more)
Apical part of cell GO:0045177
The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.
13 A0A091EVW2 (/ISS) A0A091GTE7 (/ISS) A0A091HP59 (/ISS) A0A091K3J9 (/ISS) A0A091RXH8 (/ISS) A0A091XPS4 (/ISS) A0A093IMK0 (/ISS) A0A093PK98 (/ISS) A0A099ZA67 (/ISS) R0LE95 (/ISS)
(3 more)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
13 A0A091EVW2 (/ISS) A0A091GTE7 (/ISS) A0A091HP59 (/ISS) A0A091K3J9 (/ISS) A0A091RXH8 (/ISS) A0A091XPS4 (/ISS) A0A093IMK0 (/ISS) A0A093PK98 (/ISS) A0A099ZA67 (/ISS) R0LE95 (/ISS)
(3 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
5 P00490 (/IDA) P06738 (/IDA) P09811 (/IDA) P09812 (/IDA) P11216 (/IDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
3 P06737 (/IDA) P11216 (/IDA) P11217 (/IDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
3 Q8CI94 (/ISO) Q9ET01 (/ISO) Q9WUB3 (/ISO)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
2 P06737 (/TAS) P11216 (/TAS)
Intracellular GO:0005622
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
2 P34114 (/IDA) Q00766 (/IDA)
Cell GO:0005623
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
2 E1BSN7 (/IDA) Q5ZME4 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 P06737 (/TAS) P11217 (/TAS)
Apical part of cell GO:0045177
The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.
2 E1BSN7 (/IDA) Q5ZME4 (/IDA)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
2 E1BSN7 (/IDA) Q5ZME4 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q8CI94 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 P00490 (/IDA)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
1 A0A1D8PQQ3 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 P11216 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 Q8CI94 (/ISO)
Sarcoplasmic reticulum GO:0016529
A fine reticular network of membrane-limited elements that pervades the sarcoplasm of a muscle cell; continuous over large portions of the cell and with the nuclear envelope; that part of the endoplasmic reticulum specialized for calcium release, uptake and storage.
1 P09812 (/IDA)
Z disc GO:0030018
Platelike region of a muscle sarcomere to which the plus ends of actin filaments are attached.
1 Q9WUB3 (/ISO)
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
1 P53534 (/IDA)
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
1 Q8CI94 (/ISO)
Hyphal cell wall GO:0030446
The cell wall surrounding a fungal hypha.
1 A0A1D8PQQ3 (/IDA)
Secretory granule lumen GO:0034774
The volume enclosed by the membrane of a secretory granule.
1 P06737 (/TAS)
Azurophil granule lumen GO:0035578
The volume enclosed by the membrane of an azurophil granule, a primary lysosomal granule found in neutrophil granulocytes that contains a wide range of hydrolytic enzymes and is released into the extracellular fluid.
1 P11216 (/TAS)
Protein complex GO:0043234
A stable macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.
1 Q9XTL9 (/IDA)
Skeletal muscle myofibril GO:0098723
A myofibril of a skeletal muscle fiber.
1 P00489 (/IDA)
Ficolin-1-rich granule lumen GO:1904813
Any membrane-enclosed lumen that is part of a ficolin-1-rich granule.
1 P06737 (/TAS)