The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 115660: Abhydrolase domain-containing protein 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 19 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Steroid hormone receptor activity GO:0003707
Combining with a steroid hormone and transmitting the signal within the cell to initiate a change in cell activity or function.
5 Q05AK6 (/ISS) Q4R2Y9 (/ISS) Q5EA42 (/ISS) Q802V6 (/ISS) Q9QXM0 (/ISS)
Hormone binding GO:0042562
Interacting selectively and non-covalently with any hormone, naturally occurring substances secreted by specialized cells that affect the metabolism or behavior of other cells possessing functional receptors for the hormone.
5 Q05AK6 (/ISS) Q4R2Y9 (/ISS) Q5EA42 (/ISS) Q802V6 (/ISS) Q9QXM0 (/ISS)
Acylglycerol lipase activity GO:0047372
Catalysis of the reaction: H2O + acylglycerol = a fatty acid + glycerol.
5 Q05AK6 (/ISS) Q4R2Y9 (/ISS) Q5EA42 (/ISS) Q802V6 (/ISS) Q9QXM0 (/ISS)
Phospholipase A2 activity GO:0004623
Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate.
2 Q0VC00 (/ISS) Q91ZH7 (/ISS)
Phosphatidylcholine 1-acylhydrolase activity GO:0008970
Catalysis of the reaction: phosphatidylcholine + H2O = 2-acylglycerophosphocholine + a carboxylate.
2 Q0VC00 (/ISS) Q91ZH7 (/ISS)
Lipase activity GO:0016298
Catalysis of the hydrolysis of a lipid or phospholipid.
2 A1Z7Q7 (/ISA) E2QCN3 (/ISA)
Steroid hormone receptor activity GO:0003707
Combining with a steroid hormone and transmitting the signal within the cell to initiate a change in cell activity or function.
1 P08910 (/IDA)
Steroid hormone receptor activity GO:0003707
Combining with a steroid hormone and transmitting the signal within the cell to initiate a change in cell activity or function.
1 Q9QXM0 (/ISO)
Phospholipase A2 activity GO:0004623
Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate.
1 Q8WU67 (/IMP)
Phospholipase A2 activity GO:0004623
Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate.
1 Q91ZH7 (/ISO)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q96SE0 (/IPI)
Phosphatidylcholine 1-acylhydrolase activity GO:0008970
Catalysis of the reaction: phosphatidylcholine + H2O = 2-acylglycerophosphocholine + a carboxylate.
1 Q8WU67 (/IMP)
Phosphatidylcholine 1-acylhydrolase activity GO:0008970
Catalysis of the reaction: phosphatidylcholine + H2O = 2-acylglycerophosphocholine + a carboxylate.
1 Q91ZH7 (/ISO)
Phosphatidylcholine 1-acylhydrolase activity GO:0008970
Catalysis of the reaction: phosphatidylcholine + H2O = 2-acylglycerophosphocholine + a carboxylate.
1 Q8WU67 (/TAS)
Lipase activity GO:0016298
Catalysis of the hydrolysis of a lipid or phospholipid.
1 Q24093 (/IMP)
Hormone binding GO:0042562
Interacting selectively and non-covalently with any hormone, naturally occurring substances secreted by specialized cells that affect the metabolism or behavior of other cells possessing functional receptors for the hormone.
1 P08910 (/IDA)
Hormone binding GO:0042562
Interacting selectively and non-covalently with any hormone, naturally occurring substances secreted by specialized cells that affect the metabolism or behavior of other cells possessing functional receptors for the hormone.
1 Q9QXM0 (/ISO)
Acylglycerol lipase activity GO:0047372
Catalysis of the reaction: H2O + acylglycerol = a fatty acid + glycerol.
1 P08910 (/IDA)
Acylglycerol lipase activity GO:0047372
Catalysis of the reaction: H2O + acylglycerol = a fatty acid + glycerol.
1 Q9QXM0 (/ISO)

There are 24 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to progesterone GO:0032570
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.
5 Q05AK6 (/ISS) Q4R2Y9 (/ISS) Q5EA42 (/ISS) Q802V6 (/ISS) Q9QXM0 (/ISS)
Steroid hormone mediated signaling pathway GO:0043401
A series of molecular signals mediated by a steroid hormone binding to a receptor.
5 Q05AK6 (/ISS) Q4R2Y9 (/ISS) Q5EA42 (/ISS) Q802V6 (/ISS) Q9QXM0 (/ISS)
Acylglycerol catabolic process GO:0046464
The chemical reactions and pathways resulting in the breakdown of acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids.
5 Q05AK6 (/ISS) Q4R2Y9 (/ISS) Q5EA42 (/ISS) Q802V6 (/ISS) Q9QXM0 (/ISS)
Lipid metabolic process GO:0006629
The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
2 A1Z7Q7 (/ISA) E2QCN3 (/ISA)
Phosphatidylcholine metabolic process GO:0046470
The chemical reactions and pathways involving phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline. They are important constituents of cell membranes.
2 Q8WU67 (/IMP) Q91ZH7 (/IMP)
Lipid metabolic process GO:0006629
The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
1 Q24093 (/IMP)
Phosphatidylcholine biosynthetic process GO:0006656
The chemical reactions and pathways resulting in the formation of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.
1 Q8WU67 (/TAS)
Acrosome reaction GO:0007340
The discharge, by sperm, of a single, anterior secretory granule following the sperm's attachment to the zona pellucida surrounding the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents into the egg.
1 Q9QXM0 (/IMP)
Response to wounding GO:0009611
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
1 Q9QXM0 (/IMP)
Response to wounding GO:0009611
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
1 Q5EA42 (/ISS)
Chaeta development GO:0022416
The process whose specific outcome is the progression of a chaeta over time, from its formation to the mature structure. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell.
1 Q24093 (/IGI)
Negative regulation of cell migration GO:0030336
Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration.
1 Q9QXM0 (/IMP)
Negative regulation of cell migration GO:0030336
Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration.
1 Q5EA42 (/ISS)
Response to progesterone GO:0032570
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.
1 P08910 (/IDA)
Response to progesterone GO:0032570
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.
1 Q9QXM0 (/ISO)
Wing disc development GO:0035220
Progression of the wing disc over time, from its initial formation through to its metamorphosis to form adult structures including the wing hinge, wing blade and pleura.
1 Q24093 (/IGI)
Steroid hormone mediated signaling pathway GO:0043401
A series of molecular signals mediated by a steroid hormone binding to a receptor.
1 P08910 (/IDA)
Steroid hormone mediated signaling pathway GO:0043401
A series of molecular signals mediated by a steroid hormone binding to a receptor.
1 Q9QXM0 (/ISO)
Acylglycerol catabolic process GO:0046464
The chemical reactions and pathways resulting in the breakdown of acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids.
1 P08910 (/IDA)
Acylglycerol catabolic process GO:0046464
The chemical reactions and pathways resulting in the breakdown of acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids.
1 Q9QXM0 (/ISO)
Phosphatidylcholine metabolic process GO:0046470
The chemical reactions and pathways involving phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline. They are important constituents of cell membranes.
1 Q91ZH7 (/ISO)
Phosphatidylcholine metabolic process GO:0046470
The chemical reactions and pathways involving phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline. They are important constituents of cell membranes.
1 Q0VC00 (/ISS)
Sperm capacitation GO:0048240
A process required for sperm to reach fertilization competence. Sperm undergo an incompletely understood series of morphological and molecular maturational processes, termed capacitation, involving, among other processes, protein tyrosine phosphorylation and increased intracellular calcium.
1 P08910 (/IDA)
Sperm capacitation GO:0048240
A process required for sperm to reach fertilization competence. Sperm undergo an incompletely understood series of morphological and molecular maturational processes, termed capacitation, involving, among other processes, protein tyrosine phosphorylation and increased intracellular calcium.
1 Q9QXM0 (/ISO)

There are 10 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Acrosomal vesicle GO:0001669
A structure in the head of a spermatozoon that contains acid hydrolases, and is concerned with the breakdown of the outer membrane of the ovum during fertilization. It lies just beneath the plasma membrane and is derived from the lysosome.
1 Q9QXM0 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q8WU67 (/TAS)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 Q6UXT9 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 Q5F2F2 (/ISO)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q96SE0 (/NAS)
Sperm flagellum GO:0036126
A microtubule-based flagellum (or cilium) that is part of a sperm, a mature male germ cell that develops from a spermatid.
1 P08910 (/IDA)
Sperm flagellum GO:0036126
A microtubule-based flagellum (or cilium) that is part of a sperm, a mature male germ cell that develops from a spermatid.
1 Q9QXM0 (/ISO)
Phagocytic vesicle GO:0045335
A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis.
1 Q54H38 (/IDA)
Sperm plasma membrane GO:0097524
A plasma membrane that is part of a sperm cell.
1 P08910 (/IDA)
Sperm plasma membrane GO:0097524
A plasma membrane that is part of a sperm cell.
1 Q9QXM0 (/ISO)
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