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CATH Superfamily 3.40.50.1820

Alpha/Beta hydrolase fold, catalytic domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 115660: Abhydrolase domain-containing protein 1

There are 6 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Acylglycerol lipase. [EC: 3.1.1.23]
Hydrolyzes glycerol monoesters of long-chain fatty acids.
    		 16 A0A024RC89 A0A096NN62 A0A0D9RX75 B2GTD2 G3R7Q2 G7MVW6 G7P9E4 H2QA16 L8HPH6 P08910
    (6 more...)
    Phospholipase A(1). [EC: 3.1.1.32]
    Phosphatidylcholine + H(2)O = 2-acylglycerophosphocholine + a carboxylate.
    • Has a much broader specificity than EC 3.1.1.4.
    		 3 Q0VC00 Q8WU67 Q91ZH7
    Alcohol O-acetyltransferase. [EC: 2.3.1.84]
    Acetyl-CoA + an alcohol = CoA + an acetyl ester.
    • Acts on a range of short-chain aliphatic alcohols, including methanol and ethanol.
    		 3 A0A099LKP8 E0UP24 G0R5L7
    Phospholipase A(2). [EC: 3.1.1.4]
    Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate.
    • Also acts on phosphatidylethanolamine, choline plasmalogen and phosphatides, removing the fatty acid attached to the 2-position.
    		 3 Q0VC00 Q8WU67 Q91ZH7
    Carboxylesterase. [EC: 3.1.1.1]
    A carboxylic ester + H(2)O = an alcohol + a carboxylate.
    • Wide specificity; also hydrolyzes vitamin A esters.
    • The enzymes from microsomes also catalyze the reactions of EC 3.1.1.2, EC 3.1.1.5, EC 3.1.1.6, EC 3.1.1.23, EC 3.1.1.28, EC 3.1.2.2, EC 3.5.1.4, and EC 3.5.1.13.
    • Formerly EC 3.1.1.12.
    		 3 A0A031GAI1 A0A031J7M0 G8Q3N8
    Feruloyl esterase. [EC: 3.1.1.73]
    Feruloyl-polysaccharide + H(2)O = ferulate + polysaccharide.
    • Catalyzes the hydrolysis of the 4-hydroxy-3-methoxycinnamoyl (feruloyl) group from an esterified sugar, which is usually arabinose in 'natural' substrates.
    • p-nitrophenol acetate and methyl ferulate are poorer substrates.
    • All microbial ferulate esterases are secreted into the culture medium.
    • They are sometimes called hemicellulase accessory enzymes, since they help xylanases and pectinases to break down plant cell wall hemicellulose.
    		 1 B0ERM0
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