The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Vaccinia Virus protein VP39
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 135817: O-methyltransferase family protein, expressed

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 18 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Methyltransferase activity GO:0008168
Catalysis of the transfer of a methyl group to an acceptor molecule.
5 Q0IP69 (/IDA) Q54B59 (/IDA) Q9LPU5 (/IDA) Q9LPU7 (/IDA) Q9X5T6 (/IDA)
O-methyltransferase activity GO:0008171
Catalysis of the transfer of a methyl group to the oxygen atom of an acceptor molecule.
5 A8QW52 (/IDA) A8QW53 (/IDA) Q6WUC1 (/IDA) Q6WUC2 (/IDA) Q9X5T6 (/IDA)
Acetylserotonin O-methyltransferase activity GO:0017096
Catalysis of the reaction: S-adenosyl-L-methionine + N-acetylserotonin = S-adenosyl-L-homocysteine + melatonin. Melatonin is also known as N-acetyl-5-methoxytryptamine.
5 Q6EPG8 (/IDA) Q6ZD89 (/IDA) Q8VWG4 (/IDA) Q8VWJ6 (/IDA) Q9T003 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 Q9LPU5 (/IPI) Q9LPU8 (/IPI)
S-adenosylmethionine-dependent methyltransferase activity GO:0008757
Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.
2 A8QW52 (/IDA) A8QW53 (/IDA)
Isoflavone 4'-O-methyltransferase activity GO:0030746
Catalysis of the reaction: S-adenosyl-L-methionine + isoflavone = S-adenosyl-L-homocysteine + 4'-O-methylisoflavone.
2 Q84KK4 (/IDA) Q84KK6 (/IDA)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
2 Q6WUC1 (/IDA) Q6WUC2 (/IDA)
Drug binding GO:0008144
Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
1 O49010 (/IDA)
O-methyltransferase activity GO:0008171
Catalysis of the transfer of a methyl group to the oxygen atom of an acceptor molecule.
1 Q9SRD4 (/IMP)
S-methyltransferase activity GO:0008172
Catalysis of the transfer of a methyl group to the sulfur atom of an acceptor molecule.
1 Q1WMA5 (/IDA)
Luteolin O-methyltransferase activity GO:0030744
Catalysis of the reaction: S-adenosyl-L-methionine + luteolin = 4',5,7-trihydroxy-3'-methoxyflavone + S-adenosyl-L-homocysteine + H(+).
1 Q6ZD89 (/IDA)
Licodione 2'-O-methyltransferase activity GO:0030751
Catalysis of the reaction: S-adenosyl-L-methionine(1+) + licodione = 2'-O-methyllicodione + S-adenosyl-L-homocysteine + H(+).
1 P93324 (/IDA)
8-hydroxyquercitin 8-O-methyltransferase activity GO:0030761
Catalysis of the reaction: 3,3',4',5,7,8-hexahydroxyflavone + S-adenosyl-L-methionine(1+) = 3,3',4',5,7-pentahydroxy-8-methoxyflavone + S-adenosyl-L-homocysteine + H(+).
1 Q6VMW0 (/IDA)
Myricetin 3'-O-methyltransferase activity GO:0033799
Catalysis of the reaction: S-adenosyl-L-methionine + myricetin = S-adenosyl-L-homocysteine + laricitrin.
1 Q8GSN1 (/IDA)
Isoflavone 7-O-methyltransferase activity GO:0033800
Catalysis of the reaction: S-adenosyl-L-methionine + a 7-hydroxyisoflavone = S-adenosyl-L-homocysteine + a 7-methoxyisoflavone.
1 Q84KK5 (/IDA)
Isoliquiritigenin 2'-O-methyltransferase activity GO:0033802
Catalysis of the reaction: S-adenosyl-L-methionine + isoliquiritigenin = 2'-O-methylisoliquiritigenin + S-adenosyl-L-homocysteine + H(+).
1 P93324 (/IDA)
Caffeate O-methyltransferase activity GO:0047763
Catalysis of the reaction: S-adenosyl-L-methionine + 3,4-dihydroxy-trans-cinnamate = S-adenosyl-L-homocysteine + 3-methoxy-4-hydroxy-trans-cinnamate.
1 I1I1F5 (/IDA)
Caffeate O-methyltransferase activity GO:0047763
Catalysis of the reaction: S-adenosyl-L-methionine + 3,4-dihydroxy-trans-cinnamate = S-adenosyl-L-homocysteine + 3-methoxy-4-hydroxy-trans-cinnamate.
1 Q6ZD89 (/IGC)

There are 22 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Melatonin biosynthetic process GO:0030187
The chemical reactions and pathways resulting in the formation of melatonin (N-acetyl-5-methoxytryptamine).
4 Q6EPG8 (/IDA) Q8VWG4 (/IDA) Q8VWJ6 (/IDA) Q9T003 (/IDA)
Methylation GO:0032259
The process in which a methyl group is covalently attached to a molecule.
3 A8QW52 (/IDA) A8QW53 (/IDA) Q6VMW0 (/IDA)
Isoflavonoid phytoalexin biosynthetic process GO:0009701
The chemical reactions and pathways resulting in the formation of isoflavonoid phytoalexins, a group of water-soluble phenolic derivatives isomeric with flavonoids that possess antibiotic activity and are produced by plant tissues in response to infection.
2 Q84KK4 (/IDA) Q84KK6 (/IDA)
Alkaloid biosynthetic process GO:0009821
The chemical reactions and pathways resulting in the formation of alkaloids, nitrogen-containing natural products which are not otherwise classified as nonprotein amino acids, amines, peptides, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones, or primary metabolite (such as purine or pyrimidine bases).
2 Q6WUC1 (/IDA) Q6WUC2 (/IDA)
Indole glucosinolate metabolic process GO:0042343
The chemical reactions and pathways resulting in the formation of indole glucosinolates. Glucosinolates are sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan; indoles are biologically active substances based on 2,3-benzopyrrole, formed during the catabolism of tryptophan.
2 Q9LPU5 (/IDA) Q9LPU7 (/IDA)
Response to wounding GO:0009611
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
1 Q84N28 (/IDA)
Response to herbicide GO:0009635
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a herbicide stimulus. Herbicides are chemicals used to kill or control the growth of plants.
1 O49010 (/IDA)
Isoflavonoid biosynthetic process GO:0009717
The chemical reactions and pathways resulting in the formation of isoflavonoids, a group of water-soluble phenolic derivatives, isomeric with flavonoids.
1 Q84KK5 (/IDA)
Response to ethylene GO:0009723
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethylene (ethene) stimulus.
1 Q84N28 (/IDA)
Response to salicylic acid GO:0009751
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salicylic acid stimulus.
1 Q84N28 (/IDA)
Indole glucosinolate biosynthetic process GO:0009759
The chemical reactions and pathways resulting in the formation of indole glucosinolates, sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan.
1 Q9SRD4 (/IMP)
Lignin biosynthetic process GO:0009809
The chemical reactions and pathways resulting in the formation of lignins, a class of polymers formed by the dehydrogenetive radical polymerization of various phenylpropanoid monomers.
1 Q6ZD89 (/IDA)
Lignin biosynthetic process GO:0009809
The chemical reactions and pathways resulting in the formation of lignins, a class of polymers formed by the dehydrogenetive radical polymerization of various phenylpropanoid monomers.
1 O49010 (/TAS)
Flavonoid metabolic process GO:0009812
The chemical reactions and pathways involving flavonoids, a group of water-soluble phenolic derivatives containing a flavan skeleton including flavones, flavonols and flavanoids, and anthocyanins.
1 Q6VMW0 (/IDA)
Aromatic compound biosynthetic process GO:0019438
The chemical reactions and pathways resulting in the formation of aromatic compounds, any substance containing an aromatic carbon ring.
1 Q54B59 (/IDA)
Melatonin biosynthetic process GO:0030187
The chemical reactions and pathways resulting in the formation of melatonin (N-acetyl-5-methoxytryptamine).
1 Q6ZD89 (/IMP)
Response to hydrogen peroxide GO:0042542
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
1 Q84N28 (/IDA)
Mycotoxin biosynthetic process GO:0043386
The chemical reactions and pathways resulting in the formation of a mycotoxin, any poisonous substance produced by a fungus.
1 Q4WMJ5 (/IEP)
Mycotoxin biosynthetic process GO:0043386
The chemical reactions and pathways resulting in the formation of a mycotoxin, any poisonous substance produced by a fungus.
1 Q4WMJ5 (/IGC)
Secondary metabolite biosynthetic process GO:0044550
The chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon.
1 Q4WYG1 (/IMP)
Flavonol biosynthetic process GO:0051555
The chemical reactions and pathways resulting in the formation of flavonols, a member of a class of vascular pigments formed by consecutive oxidative processes from the flavonoid intermediates flavanones and dihydroflavonols. Flavonols are the most widespread of the flavonoids and have a wide array of physiological activities.
1 Q6ZD89 (/IDA)
Quinone biosynthetic process GO:1901663
The chemical reactions and pathways resulting in the formation of quinone.
1 Q9X5T6 (/IDA)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
4 Q6EPG8 (/IDA) Q8VWG4 (/IDA) Q8VWJ6 (/IDA) Q9T003 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q9MAP0 (/IDA)