The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Vaccinia Virus protein VP39
".
FunFam 135817: O-methyltransferase family protein, expressed
There are 33 EC terms in this cluster
Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
EC Term | Annotations | Evidence |
---|---|---|
Caffeate O-methyltransferase.
[EC: 2.1.1.68]
S-adenosyl-L-methionine + 3,4-dihydroxy-trans-cinnamate = S-adenosyl-L- homocysteine + 3-methoxy-4-hydroxy-trans-cinnamate.
|
150 |
A0A068U9K4
A0A068U9K4
A0A0B2NUU9
A0A0B2NUU9
A0A0B2NZX2
A0A0B2NZX2
A0A0B2NZY1
A0A0B2NZY1
A0A0B2PJP3
A0A0B2PJP3 (140 more...) |
Quercetin 3-O-methyltransferase.
[EC: 2.1.1.76]
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L- homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone.
|
112 |
A0A0B2NPP8
A0A0B2NPP8
A0A0B2NUU9
A0A0B2NUU9
A0A0B2NZX2
A0A0B2NZX2
A0A0B2NZY1
A0A0B2NZY1
A0A0B2P6P4
A0A0B2P6P4 (102 more...) |
Catechol O-methyltransferase.
[EC: 2.1.1.6]
S-adenosyl-L-methionine + a catechol = S-adenosyl-L-homocysteine + a guaiacol.
|
60 |
A0A0A6Z5Z8
A0A0A6Z5Z8
A0A0A6Z5Z9
A0A0A6Z5Z9
A0A0A6Z632
A0A0A6Z632
A0A0A6Z653
A0A0A6Z653
A0A0A6Z6H7
A0A0A6Z6H7 (50 more...) |
(Iso)eugenol O-methyltransferase.
[EC: 2.1.1.146]
S-adenosyl-L-methionine + isoeugenol = S-adenosyl-L-homocysteine + isomethyleugenol.
|
40 |
A0A1B6PFT6
A0A1B6PFT6
A8QW52
A8QW52
B9RGB0
B9RGB0
B9RVQ8
B9RVQ8
B9RVR3
B9RVR3 (30 more...) |
O-demethylpuromycin O-methyltransferase.
[EC: 2.1.1.38]
S-adenosyl-L-methionine + O-demethylpuromycin = S-adenosyl-L-homocysteine + puromycin.
|
28 |
A0A077MZY9
A0A077MZY9
A0A077NDA9
A0A077NDA9
A0A077NZ20
A0A077NZ20
A0A077P4A2
A0A077P4A2
A0A077P740
A0A077P740 (18 more...) |
Isoflavone 4'-O-methyltransferase.
[EC: 2.1.1.46]
S-adenosyl-L-methionine + a 4'-hydroxyisoflavone = S-adenosyl-L- homocysteine + a 4'-methoxyisoflavone.
|
14 |
A0A072UNK8
A0A072UNK8
I3RZV3
I3RZV3
K9K000
K9K000
O24305
O24305
Q29U70
Q29U70 (4 more...) |
3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase.
[EC: 2.1.1.116]
S-adenosyl-L-methionine + 3'-hydroxy-N-methyl-(S)-coclaurine = S-adenosyl-L-homocysteine + (S)-reticuline.
|
12 |
A0A0B4VG66
A0A0B4VG66
A0A0B4VGZ0
A0A0B4VGZ0
Q5C9L4
Q5C9L4
Q7XB10
Q7XB10
Q7XB11
Q7XB11 (2 more...) |
(RS)-norcoclaurine 6-O-methyltransferase.
[EC: 2.1.1.128]
S-adenosyl-L-methionine + (RS)-norcoclaurine = S-adenosyl-L-homocysteine + (RS)-coclaurine.
|
12 |
A0A0B4VG62
A0A0B4VG62
A0A0B4VGY7
A0A0B4VGY7
B9SUY0
B9SUY0
Q5C9L7
Q5C9L7
Q6WUC1
Q6WUC1 (2 more...) |
2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase.
[EC: 2.1.1.212]
S-adenosyl-L-methionine + 2,4',7-trihydroxyisoflavanone = S-adenosyl-L- homocysteine + 2,7-dihydroxy-4'-methoxyisoflavanone.
|
10 | A0A072UNK8 A0A072UNK8 I3RZV3 I3RZV3 Q29U70 Q29U70 Q84KK4 Q84KK4 Q84KK6 Q84KK6 |
Isoflavone 7-O-methyltransferase.
[EC: 2.1.1.150]
S-adenosyl-L-methionine + a 7-hydroxyisoflavone = S-adenosyl-L- homocysteine + a 7-methoxyisoflavone.
|
10 | B9S9B7 B9S9B7 O22308 O22308 O22309 O22309 O24529 O24529 Q84KK5 Q84KK5 |
Acetylserotonin O-methyltransferase.
[EC: 2.1.1.4]
S-adenosyl-L-methionine + N-acetylserotonin = S-adenosyl-L-homocysteine + melatonin.
|
10 | A0A0E0QEJ7 A0A0E0QEJ7 Q6EPG8 Q6EPG8 Q6ZD89 Q6ZD89 Q8VWG4 Q8VWG4 Q8VWJ6 Q8VWJ6 |
5-hydroxyfuranocoumarin 5-O-methyltransferase.
[EC: 2.1.1.69]
(1) S-adenosyl-L-methionine + a 5-hydroxyfurocoumarin = S-adenosyl-L- homocysteine + a 5-methoxyfurocoumarin. (2) S-adenosyl-L-methionine + bergaptol = S-adenosyl-L-homocysteine + bergapten.
|
8 | A0A166U5H3 A0A166U5H3 A8J6X1 A8J6X1 J9PHM5 J9PHM5 Q6T1F6 Q6T1F6 |
(S)-scoulerine 9-O-methyltransferase.
[EC: 2.1.1.117]
S-adenosyl-L-methionine + (S)-scoulerine = S-adenosyl-L-homocysteine + (S)-tetrahydrocolumbamine.
|
4 | Q39522 Q39522 Q5C9L2 Q5C9L2 |
Flavone 3'-O-methyltransferase.
[EC: 2.1.1.42]
S-adenosyl-L-methionine + 3'-hydroxyflavone = S-adenosyl-L-homocysteine + 3'-methoxyflavone.
|
4 | A0A0E0QEJ7 A0A0E0QEJ7 Q6ZD89 Q6ZD89 |
Anthranilate N-methyltransferase.
[EC: 2.1.1.111]
S-adenosyl-L-methionine + anthranilate = S-adenosyl-L-homocysteine + N-methylanthranilate.
|
4 | A9X7L0 A9X7L0 M4HXR6 M4HXR6 |
5-pentadecatrienyl resorcinol O-methyltransferase.
[EC: 2.1.1.n7]
S-adenosyl-L-methionine + (8Z,11Z)-5-(pentadeca-8,11,14-trien-1- yl)resorcinol = S-adenosyl-L-homocysteine + (8Z,11Z)-5-(pentadeca- 8,11,14-trien-1-yl)resorcinol-3-methyl ether.
|
4 | A8QW53 A8QW53 C5YBN8 C5YBN8 |
Calcium-transporting ATPase.
[EC: 3.6.3.8]
ATP + H(2)O + Ca(2+)(Side 1) = ADP + phosphate + Ca(2+)(Side 2).
|
4 | K7TI47 K7TI47 K7TWC7 K7TWC7 |
(+)-6a-hydroxymaackiain 3-O-methyltransferase.
[EC: 2.1.1.270]
S-adenosyl-L-methionine + (+)-6a-hydroxymaackiain = S-adenosyl-L- homocysteine + (+)-pisatin.
|
4 | O24305 O24305 P0DH60 P0DH60 |
Inositol 4-methyltransferase.
[EC: 2.1.1.129]
S-adenosyl-L-methionine + myo-inositol = S-adenosyl-L-homocysteine + 1D-4-O-methyl-myo-inositol.
|
2 | P45986 P45986 |
Tetrahydrocolumbamine 2-O-methyltransferase.
[EC: 2.1.1.89]
S-adenosyl-L-methionine + 5,8,13,13a-tetrahydrocolumbamine = S-adenosyl- L-homocysteine + tetrahydropalmatine.
|
2 | Q8H9A8 Q8H9A8 |
2,4,7-trihydroxy-1,4-benzoxazin-3-one-glucoside 7-O-methyltransferase.
[EC: 2.1.1.241]
S-adenosyl-L-methionine + (2R)-4,7-dihydroxy-3-oxo-3,4-dihydro-2H-1,4- benzoxazin-2-yl beta-D-glucopyranoside = S-adenosyl-L-homocysteine + (2R)-4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl beta-D- glucopyranoside.
|
2 | B1P123 B1P123 |
Isoliquiritigenin 2'-O-methyltransferase.
[EC: 2.1.1.154]
S-adenosyl-L-methionine + isoliquiritigenin = S-adenosyl-L-homocysteine + 2'-O-methylisoliquiritigenin.
|
2 | P93324 P93324 |
Flavonoid 3',5'-methyltransferase.
[EC: 2.1.1.267]
(1) S-adenosyl-L-methionine + a 3'-hydroxyflavonoid = S-adenosyl-L- homocysteine + a 3'-methoxyflavonoid. (2) S-adenosyl-L-methionine + a 5'-hydroxy-3'-methoxyflavonoid = S-adenosyl-L-homocysteine + a 3',5'-dimethoxyflavonoid.
|
2 | Q8GSN1 Q8GSN1 |
Trans-anol O-methyltransferase.
[EC: 2.1.1.279]
(1) S-adenosyl-L-methionine + trans-anol = S-adenosyl-L-homocysteine + trans-anethole. (2) S-adenosyl-L-methionine + isoeugenol = S-adenosyl-L-homocysteine + isomethyleugenol.
|
2 | B8RCD3 B8RCD3 |
(R,S)-reticuline 7-O-methyltransferase.
[EC: 2.1.1.291]
(1) S-adenosyl-L-methionine + (S)-reticuline = S-adenosyl-L-homocysteine + (S)-laudanine. (2) S-adenosyl-L-methionine + (R)-reticuline = S-adenosyl-L-homocysteine + (R)-laudanine.
|
2 | Q6WUC2 Q6WUC2 |
8-hydroxyquercetin 8-O-methyltransferase.
[EC: 2.1.1.88]
S-adenosyl-L-methionine + 3,3',4',5,7,8-hexahydroxyflavone = S-adenosyl- L-homocysteine + 3,3',4',5,7-pentahydroxy-8-methoxyflavone.
|
2 | Q6VMW0 Q6VMW0 |
Flavonoid 4'-O-methyltransferase.
[EC: 2.1.1.231]
S-adenosyl-L-methionine + a 4'-hydroxyflavanone = S-adenosyl-L- homocysteine + a 4'-methoxyflavanone.
|
2 | C6TAY1 C6TAY1 |
Mitomycin 6-O-methyltransferase.
[EC: 2.1.1.316]
(1) S-adenosyl-L-methionine + 6-demethylmitomycin A = S-adenosyl-L- homocysteine + mitomycin A. (2) S-adenosyl-L-methionine + 6-demethylmitomycin B = S-adenosyl-L- homocysteine + mitomycin B.
|
2 | Q9X5T6 Q9X5T6 |
Trans-resveratrol di-O-methyltransferase.
[EC: 2.1.1.240]
2 S-adenosyl-L-methionine + trans-resveratrol = 2 S-adenosyl-L- homocysteine + pterostilbene.
|
2 | B6VJS4 B6VJS4 |
Columbamine O-methyltransferase.
[EC: 2.1.1.118]
S-adenosyl-L-methionine + columbamine = S-adenosyl-L-homocysteine + palmatine.
|
2 | Q8H9A8 Q8H9A8 |
Licodione 2'-O-methyltransferase.
[EC: 2.1.1.65]
S-adenosyl-L-methionine + licodione = S-adenosyl-L-homocysteine + 2'-O- methyllicodione.
|
2 | P93324 P93324 |
Tricetin 3',4',5'-O-trimethyltransferase.
[EC: 2.1.1.169]
3 S-adenosyl-L-methionine + tricetin = 3 S-adenosyl-L-homocysteine + 3',4',5'-O-trimethyltricetin.
|
2 | Q38J50 Q38J50 |
Naringenin 7-O-methyltransferase.
[EC: 2.1.1.232]
S-adenosyl-L-methionine + (2S)-naringenin = S-adenosyl-L-homocysteine + (2S)-sakuranetin.
|
2 | Q0IP69 Q0IP69 |