The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Leucine Dehydrogenase, chain A, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 8326: Methylenetetrahydrofolatedehydrogenase / methenylt...

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Methenyltetrahydrofolate cyclohydrolase. [EC: 3.5.4.9]
5,10-methenyltetrahydrofolate + H(2)O = 10-formyltetrahydrofolate.
    106 A0A034UHY0 A0A062X0C6 A0A075V1Q1 A0A076EVG1 A0A076N178 A0A093CXG8 A0A094M6K2 A0A0B4CRJ1 A0A0B8MZZ7 A0A0C1C1Q4
    (96 more...)
    Methylenetetrahydrofolate dehydrogenase (NADP(+)). [EC: 1.5.1.5]
    5,10-methylenetetrahydrofolate + NADP(+) = 5,10- methenyltetrahydrofolate + NADPH.
      104 A0A034UHY0 A0A062X0C6 A0A075V1Q1 A0A076EVG1 A0A076N178 A0A093CXG8 A0A094M6K2 A0A0B4CRJ1 A0A0B8MZZ7 A0A0C1C1Q4
      (94 more...)