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CATH Superfamily 3.40.50.10860

Leucine Dehydrogenase, chain A, domain 1

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Leucine Dehydrogenase, chain A, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
8333
Shikimate dehydrogenase
NADP(+
14707
EC
3D
 2gptA02 - 95.0
8110
Bifunctional protein FolD 2
10259
EC
 - - 98.2
8003
Branched-chain amino acid dehydrogenase
7494
EC
3D
 1lehA01 - 88.6
8285
NADP-specific glutamate dehydrogenase 1
7240
EC
3D
 2yfhA02 - 87.5
8334
Shikimate dehydrogenase
NADP(+
5037
EC
3D
 1nvtA01 - 94.1
8226
Bifunctional protein FolD 1
3416
EC
3D
 2c2xA02 - 98.1
8178
Bifunctional protein FolD 2
3370
EC
 - - 95.8
7793
Bifunctional protein FolD
2056
EC
 - - 54.4
8189
Bifunctional protein FolD
1535
EC
 - - 97.7
7839
Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD
P
1442
EC
 - - 66.7
8170
Bifunctional protein FolD 2
1322
EC
 - - 95.5
8218
C-1-tetrahydrofolate synthase, cytoplasmic
969
EC
 - - 92.2
8197
Bifunctional protein FolD protein
940
EC
3D
 3l07A02 - 93.3
8273
Putative PENTAFUNCTIONAL AROM polypeptide
809
EC
 - - 96.7
8235
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial
783
EC
3D
 5tc4A02 - 98.5
8332
Bifunctional protein FolD protein
672
EC
 - - 98.8
8284
Probable NAD-specific glutamate dehydrogenase
470
EC
 - - 88.7
8366
Shikimate dehydrogenase
NADP(+
467
EC
3D
 3phgA01 - 85.1
8126
Bifunctional protein FolD
444
EC
 - - 83.3
8304
Bifunctional protein FolD 2
372
EC
 - - 69.0
7589
Bifunctional protein FolD
317
EC
 - - 41.5
1536
Shikimate dehydrogenase
NADP(+
270
EC
 - - 68.3
8272
Methylenetetrahydrofolate dehydrogenase
AFU_orthologue AFUA_8G05330
267
EC
 - - 79.9
8326
Methylenetetrahydrofolatedehydrogenase / methenyltetrahydrofolate cyclohydrolase, bifunctional protein
180
EC
 - - 97.6
7728
Shikimate dehydrogenase
NADP(+
171
EC
 - - 21.1
6750
Shikimate dehydrogenase
NADP(+
132
EC
 - - 16.7
8153
Shikimate dehydrogenase
NADP(+
92
EC
 - - 49.8
8352
Shikimate dehydrogenase
NADP(+
90
EC
 - - 78.2
6008
Shikimate 5-dehydrogenase AroE
88
EC
3D
 4p4gA01 - 25.1
7846
Bifunctional protein FolD
63
EC
 - - 42.2
7805
Monofunctional C1-tetrahydrofolate synthase, mitochondrial
63
EC
 - - 58.5
7021
Shikimate 5-dehydrogenase I alpha
53
EC
 - - 1.2
8338
Bifunctional protein FolD
40
EC
 - - 97.5
8360
Shikimate 5-dehydrogenase
24
EC
 - - 68.9
8008
Bifunctional protein FolD
20
EC
 - - 22.3
7595
Bifunctional protein FolD
18
EC
 - - 17.4
7694
Bifunctional protein FolD 2
15
EC
 - - 10.9
7848
Bifunctional protein FolD
13
EC
 - - 28.7
7891
Bifunctional protein FolD
13
EC
 - - 46.7
8157
Bifunctional protein FolD
13
EC
 - - 69.2
6194
Bifunctional protein FolD
12
EC
 - - 22.9
3260
Bifunctional protein FolD
9
EC
 - - 2.4
4731
Quinate dehydrogenase
9
EC
 - - 6.0
7689
Bifunctional protein FolD
8
EC
 - - 42.5
3560
5,10-methylene-tetrahydrofolate cyclohydrolase
8
EC
 - - 3.0
4732
Bifunctional protein FolD
7
EC
 - - 3.8
8363
Bifunctional protein FolD
6
EC
 - - 42.4
3876
Bifunctional protein FolD
4
EC
 - - 2.4
4283
Bifunctional protein FolD
3
EC
 - - 0.0
4563
Quinate repressor protein
3 - - 8.3
7704
5,10-methylene-tetrahydrofolate cyclohydrolase
2
EC
 - - 2.4
8364
Bifunctional protein FolD
2
EC
 - - 42.2
7782
Bifunctional protein FolD
2
EC
 - - 19.3
3863
Bifunctional protein FolD 3
2
EC
 - - 0.0
6004
Bifunctional protein FolD
2
EC
 - - 4.3
8077
Shikimate dehydrogenase
NADP(+
2
EC
 - - 38.5
3209
Bifunctional protein FolD
2
EC
 - - 0.8
8351
Bifunctional protein FolD
2
EC
 - - 40.7
4649
Bifunctional protein FolD
1
EC
 - - 0.0
6036
Bifunctional protein FolD
1
EC
 - - 0.0
6940
Shikimate dehydrogenase
NADP(+
1
EC
 - - 0.0
3874
Bifunctional protein FolD 1
1
EC
 - - 0.0
4468
Bifunctional protein FolD
1
EC
 - - 0.0
2836
Bifunctional protein FolD
1
EC
 - - 0.0
3188
Bifunctional protein FolD
1
EC
 - - 0.0
7505
Bifunctional protein FolD 1
1
EC
 - - 0.0