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CATH Superfamily 3.40.50.10860

Leucine Dehydrogenase, chain A, domain 1

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Leucine Dehydrogenase, chain A, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 8285: NADP-specific glutamate dehydrogenase 1

There are 8 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Glutamate dehydrogenase (NAD(P)(+)). [EC: 1.4.1.3]
L-glutamate + H(2)O + NAD(P)(+) = 2-oxoglutarate + NH(3) + NAD(P)H.
    		 105 A0A075I2P1 A0A0A0XKB0 A0A0B0EMW2 A0A0C6NZX2 A0A0D2MDC4 A0A0D3F898 A0A0D3FYJ4 A0A0D5Z5P8 A0A0D5Z6E0 A0A0D9ZNS4
    (95 more...)
    Glutamate dehydrogenase. [EC: 1.4.1.2]
    L-glutamate + H(2)O + NAD(+) = 2-oxoglutarate + NH(3) + NADH.
      		 81 A0A031WDM8 A0A085C5C3 A0A0B0HPV8 A0A0D1J4E7 A0A0E1AIQ2 A0A0E3R847 A0A0E3WN58 A0A0G3VFZ9 A0A0H3MYJ3 A0A0J0XZB7
      (71 more...)
      Glutamate dehydrogenase (NADP(+)). [EC: 1.4.1.4]
      L-glutamate + H(2)O + NADP(+) = 2-oxoglutarate + NH(3) + NADPH.
        		 72 A0A024L2S9 A0A070SRX5 A0A090QWH6 A0A090WW26 A0A0A0XKB0 A0A0C6NZX2 A0A0E1LY93 A0A0E8FKJ2 A0A0F6Z681 A0A0H3LTB4
        (62 more...)
        Phosphoglycerate kinase. [EC: 2.7.2.3]
        ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.
          		 3 A0A0B0EH86 A0A1G2XKB1 A0A1G3B3L3
          Glycerol-3-phosphate dehydrogenase (NAD(P)(+)). [EC: 1.1.1.94]
          sn-glycerol 3-phosphate + NAD(P)(+) = glycerone phosphate + NAD(P)H.
          • The enzyme from Escherichia coli shows specificity for the B side of NADPH.
          		 1 A0A171A2I5
          Glycerol-3-phosphate dehydrogenase (NAD(+)). [EC: 1.1.1.8]
          sn-glycerol 3-phosphate + NAD(+) = glycerone phosphate + NADH.
          • Also acts on propane-1,2-diol phosphate and glycerone sulfate (but with a much lower affinity).
          		 1 A0A171A2I5
          Phosphatidate cytidylyltransferase. [EC: 2.7.7.41]
          CTP + phosphatidate = diphosphate + CDP-diacylglycerol.
            		 1 B3ESG9
            Glucose 1-dehydrogenase (FAD, quinone). [EC: 1.1.5.9]
            D-glucose + a quinone = D-glucono-1,5-lactone + a quinol.
            • 2,6-dichloroindophenol can act as acceptor.
            • Cf. EC 1.1.5.2.
            • Formerly EC 1.1.99.10.
            		 1 A0A171A2I5
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