The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Leucine Dehydrogenase, chain A, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 8226: Bifunctional protein FolD 1

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Methenyltetrahydrofolate cyclohydrolase. [EC: 3.5.4.9]
5,10-methenyltetrahydrofolate + H(2)O = 10-formyltetrahydrofolate.
    2094 A0A010NDY4 A0A011T5F5 A0A014LMG8 A0A021VS76 A0A022KS11 A0A022LA62 A0A022LHU6 A0A022LT45 A0A022MPN7 A0A024H4I7
    (2084 more...)
    Methylenetetrahydrofolate dehydrogenase (NADP(+)). [EC: 1.5.1.5]
    5,10-methylenetetrahydrofolate + NADP(+) = 5,10- methenyltetrahydrofolate + NADPH.
      2093 A0A010NDY4 A0A011T5F5 A0A014LMG8 A0A021VS76 A0A022KS11 A0A022LA62 A0A022LHU6 A0A022LT45 A0A022MPN7 A0A024H4I7
      (2083 more...)
      Methylenetetrahydrofolate dehydrogenase (NAD(+)). [EC: 1.5.1.15]
      5,10-methylenetetrahydrofolate + NAD(+) = 5,10-methenyltetrahydrofolate + NADH.
        2 B8Y658 E9BI44
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