The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Leucine Dehydrogenase, chain A, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 8126: Bifunctional protein FolD

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Methenyltetrahydrofolate cyclohydrolase. [EC: 3.5.4.9]
5,10-methenyltetrahydrofolate + H(2)O = 10-formyltetrahydrofolate.
    280 A0A024BWV0 A0A024C9L9 A0A060Q1B7 A0A083YG99 A0A086RU55 A0A099BF76 A0A099BLE9 A0A099DN30 A0A099TFP5 A0A099TVS4
    (270 more...)
    Methylenetetrahydrofolate dehydrogenase (NADP(+)). [EC: 1.5.1.5]
    5,10-methylenetetrahydrofolate + NADP(+) = 5,10- methenyltetrahydrofolate + NADPH.
      280 A0A024BWV0 A0A024C9L9 A0A060Q1B7 A0A083YG99 A0A086RU55 A0A099BF76 A0A099BLE9 A0A099DN30 A0A099TFP5 A0A099TVS4
      (270 more...)