The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Leucine Dehydrogenase, chain A, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 8008: Bifunctional protein FolD

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Methylenetetrahydrofolate dehydrogenase (NADP(+)). [EC: 1.5.1.5]
5,10-methylenetetrahydrofolate + NADP(+) = 5,10- methenyltetrahydrofolate + NADPH.
    12 A0A014MGG3 A0A078KHH6 A0A084EJR2 A0A0C2W6R6 A0A0F2BN13 A0A1C9LTW8 A0A1D5B5B4 E4PSE4 F4MQQ3 L5LBS3
    (2 more...)
    Methenyltetrahydrofolate cyclohydrolase. [EC: 3.5.4.9]
    5,10-methenyltetrahydrofolate + H(2)O = 10-formyltetrahydrofolate.
      12 A0A014MGG3 A0A078KHH6 A0A084EJR2 A0A0C2W6R6 A0A0F2BN13 A0A1C9LTW8 A0A1D5B5B4 E4PSE4 F4MQQ3 L5LBS3
      (2 more...)