View in Gene3D

CATH Superfamily 3.40.50.1000

HAD superfamily/HAD-like

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
HAD superfamily/HAD-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 57952: Trehalose 6-phosphate phosphatase

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Trehalose-phosphatase. [EC: 3.1.3.12]
Trehalose 6-phosphate + H(2)O = trehalose + phosphate.
    		 1789 A0A009F394 A0A009GHE1 A0A009HCD3 A0A009JIQ5 A0A009LQC3 A0A009MMX1 A0A009RH45 A0A009YBW5 A0A010GM13 A0A010JK50
    (1779 more...)
    Alpha,alpha-trehalose-phosphate synthase (UDP-forming). [EC: 2.4.1.15]
    UDP-glucose + D-glucose 6-phosphate = UDP + alpha,alpha-trehalose 6-phosphate.
    • See also EC 2.4.1.36.
    		 53 A0A062V5K9 A0A069SGT2 A0A077XRZ1 A0A081DDU3 A0A090QFG2 A0A090WD10 A0A098BZI5 A0A0B5WYD4 A0A0F4YFU6 A0A0P0LIT6
    (43 more...)
    Alpha,alpha-trehalase. [EC: 3.2.1.28]
    Alpha,alpha-trehalose + H(2)O = beta-D-glucose + alpha-D-glucose.
    • The enzyme is an anomer-inverting glucosidase that catalyzes the hydrolysis of the alpha-glucosidic O-linkage of alpha,alpha- trehalose, releasing initially equimolar amounts of alpha- and beta- D-glucose.
    • It is widely distributed in microorganisms, plants, invertebrates and vertebrates.
    		 30 A0A045IRJ9 A0A0G4E0R1 A0A0H3LAJ5 A0A0H3MEE9 A0A0H3P6N6 A0A0K2HX11 A0A0T9BG49 A0A0T9BKS5 A0A0T9BNW7 A0A0T9WKP8
    (20 more...)
    Trehalose 6-phosphate phosphorylase. [EC: 2.4.1.216]
    Alpha,alpha-trehalose 6-phosphate + phosphate = glucose 6-phosphate + beta-D-glucose 1-phosphate.
    • The enzyme from Lactococcus lactis is specific for trehalose 6-phosphate.
    • Differs from EC 2.4.1.64 in that trehalose is not a substrate.
    		 4 C1A0I1 G4I1R9 W4A7D6 W4AA76