The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
HAD superfamily/HAD-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
58048
58688
EC
3D
4bkmA02 - 91.9
57954
57689
EC
3D
4qjbA01 - 92.5
18568
54242
EC
3D
2c4nA01 - 24.5
58072
33251
EC
3D
1qq6A01 - 79.0
57801
33164
EC
3D
2b8eA01 - 86.3
20211
20474
EC
- - 55.6
57093
20465
EC
3D
2r8eA00 - 89.0
57876
18601
EC
3D
2nyvA01 - 92.8
34748
17076
EC
- - 85.1
57655
16924
EC
3D
1iwoA04 - 93.2
57212
13485 - - 83.5
57877
12156
EC
3D
3n28A01 - 95.0
57935
11543
EC
3D
2gmwA00 - 90.9
29155
HAD superfamily
10620
EC
- - 18.9
57234
10484
EC
3D
1n8nA00 - 94.9
44114
9731
EC
3D
2b0cA01 - 30.6
57810
9352
EC
3D
4bkmA01 - 96.0
57117
6539
EC
- - 36.4
31966
6483 - - 2.0
35698
5769
EC
- - 20.5
50550
5306
EC
- - 7.3
57638
5173
EC
- - 96.1
57241
4795
EC
- - 81.9
10019
3980
EC
- - 84.0
57576
3786
EC
- - 90.6
57952
3438
EC
- - 92.5
40385
3412
EC
3D
4g9bA01 - 29.0
57997
3182
EC
3D
1xviA01 - 94.3
57251
2990
EC
3D
3b8eA03 - 95.2
57497
2908
EC
3D
1t9zA00 - 75.2
57625
2904
EC
- - 92.2
57630
2653
EC
- - 88.6
57719
2214
EC
3D
2amyA01 - 91.6
57811
2154
EC
- - 79.6
57661
2027
3D
3kc2A01 - 87.8
57938
2003
EC
3D
4fypA00 - 89.2
58029
1965
EC
3D
3bwvA01 - 91.0
57196
1963
EC
- - 89.1
57641
1826
EC
- - 77.7
57940
1634
EC
3D
3shqA02 - 72.5
57376
1561
EC
3D
1fezA01 - 87.4
57598
1436
EC
3D
4qqfA00 - 86.2
57788
Cd/Co/Hg/Pb/Zn
1392
EC
- - 86.0
44148
1102
EC
- - 21.7
57918
1044
3D
3kc2A02 - 94.3
57809
788
EC
3D
3l5kA01 - 87.1
57129
743
EC
- - 57.0
58039
713 - - 48.9
57593
Mg
2+
615
EC
- - 86.0
57698
610
EC
3D
1ynsA01 - 91.7
57971
5'
3'
541
EC
3D
2jaoA01 - 87.0
57050
536
EC
- - 61.8
57299
497
EC
3D
2cn1A01 - 90.6
57882
486
EC
- - 93.4
57476
446
EC
- - 90.7
57088
399
EC
- - 63.4
57804
373
EC
3D
2qltA01 - 90.1
57845
371
EC
- - 87.1
12303
366
EC
- - 57.3
57614
361
EC
3D
3ef0A01 - 75.9
14135
359
EC
- - 70.3
57607
355
EC
3D
1yj5A01 - 92.5
57796
321
EC
3D
1s8oA01 - 68.0
57713
276 - - 73.6
57520
273
EC
3D
1l8lA01 - 83.8
57735
267
EC
- - 90.3
57310
239
EC
- - 85.6
57762
230
EC
- - 12.3
57164
227
EC
- - 68.1
57081
200
EC
- - 50.1
6373
199
EC
- - 59.6
57091
196
EC
- - 65.9
1513
196 - - 0.0
57109
183
EC
- - 21.8
57313
183
3D
2ho4A01 - 91.8
43090
180
EC
- - 0.9
10195
174
EC
- - 0.9
26179
173
EC
- - 11.0
57502
169 - - 70.3
58083
167
EC
- - 73.3
57559
156
EC
- - 83.5
17321
153
EC
- - 0.9
57387
148
EC
- - 89.1
57293
141
3D
2ho4A02 - 81.4
36019
134
EC
- - 34.4
50543
133 - - 8.2
53218
129
EC
- - 66.9
57953
126
3D
1nrwA01 - 88.1
57765
123
EC
3D
1u7oA00 - 81.6
39236
121 - - 0.0
57894
115
EC
- - 39.1
21021
106
EC
- - 20.4
57570
106
EC
- - 34.5
12430
104 - - 67.1
57596
104
EC
- - 53.8
58089
103
EC
- - 79.1
57277
102
EC
- - 31.8
39736
93
EC
- - 48.9
57622
93
EC
- - 86.6
4700
92
3D
3nuqA02 - 26.3
57826
90
EC
3D
4nv0A01 - 80.9
57463
85
EC
3D
2x4dB01 - 78.4
40266
83
EC
- - 5.7
57946
83 - - 66.8
57526
80
EC
3D
3nasA01 - 56.2
57094
78 - - 42.2
53190
76
EC
- - 66.2
1055
74 - - 14.2
57494
67
EC
- - 49.3
25575
66
EC
- - 8.4
3667
65
EC
- - 17.7
32342
64 - - 0.0
58034
61
EC
- - 93.5
10742
60
EC
3D
3ewiA00 - 31.1
57099
55
EC
3D
2w4mA01 - 50.0
1484
55
EC
- - 10.0
57032
54
EC
- - 59.6
22409
52
EC
- - 1.8
58068
50
EC
- - 83.4
5314
46
EC
3D
1k1eA00 - 15.4
58019
46
EC
- - 56.5
29175
HAD
43
EC
- - 76.3
40269
42
EC
- - 0.0
57176
40
EC
- - 31.6
57175
39
EC
- - 22.3
52719
37 - - 74.4
57555
33
EC
- - 48.2
57897
31 - - 72.5
35620
31
EC
- - 1.1
37019
30 - - 15.5
34739
27 - - 1.8
26561
26 - - 18.1
41833
25
EC
- - 0.9
38705
25 - - 0.0
15918
22
EC
3D
3ocuA00 - 17.7
31208
22
EC
3D
2ia5A02 - 4.0
57118
21 - - 26.5
18386
18
EC
- - 6.9
57573
17
EC
- - 62.9
42728
17
EC
- - 1.5
56972
16
EC
- - 38.3
1258
15 - - 9.4
54509
15
EC
- - 12.7
57186
13
EC
- - 38.9
4999
13
EC
- - 23.2
3410
12 - - 20.2
27804
11
EC
- - 12.3
57776
10 - - 38.4
23412
7 - - 9.6
27190
7 - - 5.4
52417
7
EC
- - 12.6
3573
7
EC
- - 16.6
5098
7 - - 9.0
5625
HAD
6 - - 9.6
8456
6
EC
- - 12.8
47559
5 - - 9.4
36331
5
EC
- - 0.9
4575
5 - - 1.4
57394
5 - - 53.3
8144
5
EC
- - 4.7
57378
4 - - 30.3
2980
4
EC
- - 0.0
57790
4 - - 0.0
52752
4
EC
- - 0.0
57791
3
EC
- - 30.6
49329
3
EC
- - 23.7
10686
3
EC
- - 8.5
57635
3 - - 26.3
43044
3
EC
- - 7.5
48467
2 - - 7.4
3360
2
EC
- - 6.9
50544
2 - - 7.3
49981
3'
2 - - 0.0
24298
2 - - 6.6
3966
2 - - 0.0
18116
2 - - 11.7
15942
2 - - 6.2
5912
2
EC
- - 13.0
29273
1
EC
- - 0.0
8143
1
EC
- - 0.0
41816
1 - -
31207
1 - - 0.0
17803
1 - - 0.0
11276
1
EC
- - 0.0
6931
Eurofung
1 - - 0.0
57784
1 - - 0.0