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CATH Superfamily 3.40.50.1000

HAD superfamily/HAD-like

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
HAD superfamily/HAD-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 57251: Sodium/potassium-transporting ATPase subunit alpha

There are 5 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Sodium/potassium-exchanging ATPase. [EC: 3.6.3.9]
ATP + H(2)O + Na(+)(In) + K(+)(Out) = ADP + phosphate + Na(+)(Out) + K(+)(In).
  • P-type ATPase that undergoes covalent phosphorylation during the transport cycle.
  • An enzyme from the plasma membrane of animal cells that catalyzes the efflux of three Na(+) and influx of two K(+) per ATP hydrolyzed.
  • It is involved in generating the plasma membrane electrical potential.
  • Formerly EC 3.6.1.37.
 108 A0A0B7FBD6 A0A0B7FBD6 A0A0D9S121 A0A0D9S121 A0A0F8DAY7 A0A0F8DAY7 A0A0S2Z3W6 A0A0S2Z3W6 A2VDL6 A2VDL6
(98 more...)
Hydrogen/potassium-exchanging ATPase. [EC: 3.6.3.10]
ATP + H(2)O + H(+)(In) + K(+)(Out) = ADP + phosphate + H(+)(Out) + K(+)(In).
  • P-type ATPase that undergoes covalent phosphorylation during the transport cycle.
  • Hydrolysis of ATP is coupled with the exchange of H(+) and K(+) ions.
  • Formerly EC 3.6.1.36.
 38 A0A061HTT4 A0A061HTT4 A0A089WS23 A0A089WS23 A0A0F4YVP4 A0A0F4YVP4 A8BV45 A8BV45 B0Y1A1 B0Y1A1
(28 more...)
Histone-lysine N-methyltransferase. [EC: 2.1.1.43]
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].
    		 2 G5BWK8 G5BWK8
    Transferred entry: 3.6.3.9. [EC: 3.6.1.37]
      		2 Q8QGY1 Q8QGY1
      NADH:ubiquinone reductase (H(+)-translocating). [EC: 1.6.5.3]
      NADH + ubiquinone + 5 H(+)(In) = NAD(+) + ubiquinol + 4 H(+)(Out).
      • The complex is present in mitochondria and aerobic bacteria.
      • Breakdown of the complex can release EC 1.6.99.3.
      • In photosynthetic bacteria, reversed electron transport through this enzyme can reduce NAD(+) to NADH.
      		 2 G0R4V3 G0R4V3
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