The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
HAD superfamily/HAD-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 44148: Cation transporting P-type ATPase

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Cu(2+)-exporting ATPase. [EC: 3.6.3.4]
ATP + H(2)O + Cu(2+)(Side 1) = ADP + phosphate + Cu(2+)(Side 2).
  • A P-type ATPase that undergoes covalent phosphorylation during the transport cycle.
  • The enzyme from the termophilic bacterium Archaeoglobus fulgidus is involved in copper extrusion from the cell.
103 A0A064DA41 A0A069XHX5 A0A073FR44 A0A073G848 A0A074HQN6 A0A080FJP2 A0A080FN01 A0A085GJ81 A0A085HF85 A0A085I5V3
(93 more...)
Cadmium-exporting ATPase. [EC: 3.6.3.3]
ATP + H(2)O + Cd(2+)(In) = ADP + phosphate + Cd(2+)(Out).
  • P-type ATPase that undergoes covalent phosphorylation during the transport cycle.
60 A0A064DA41 A0A085GJ81 A0A085HF85 A0A085I5V3 A0A094XV55 A0A0A1BAU5 A0A0B1MU90 A0A0D4CCM6 A0A0E0XT90 A0A0E1CS74
(50 more...)
Zinc-exporting ATPase. [EC: 3.6.3.5]
ATP + H(2)O + Zn(2+)(In) = ADP + phosphate + Zn(2+)(Out).
  • P-type ATPase that undergoes covalent phosphorylation during the transport cycle.
  • This enzyme also exports Cd(2+) and Co(2+).
18 A0A064DA41 A0A085GJ81 A0A085HF85 A0A085I5V3 A0A0A1BAU5 A0A0D4CCM6 A0A0F6TYS3 A0A0H3CRW7 A0A0M7J869 A0A0U4GFF6
(8 more...)
Ag(+)-exporting ATPase. [EC: 3.6.3.53]
ATP + H(2)O + Ag(+)(In) = ADP + phosphate + Ag(+)(Out).
  • P-type ATPase that exports Ag(+) ions from pathogenic microorganisms as well as from some animal tissues.
13 A0A0E1CS74 A0A0I9NWL3 A0A0M1THI3 A0A0W2DKM3 A0A163L1I4 A0A1D3A710 A0A1D3KUN1 A0A1E4ZAI8 A0A1F2MFD6 Q6U5P1
(3 more...)