The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
HAD superfamily/HAD-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 18386: Histidine biosynthesis bifunctional protein HisB

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Imidazoleglycerol-phosphate dehydratase. [EC: 4.2.1.19]
D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2- oxopropyl phosphate + H(2)O.
    10 A0A128H5T0 A0A128UQY8 A0A129FTQ4 A0A131N3X6 A0A182DB74 A0A1K2GFS5 G8UT89 Q5WX93 Q5X5X1 Q5ZW89
    Histidinol-phosphatase. [EC: 3.1.3.15]
    L-histidinol phosphate + H(2)O = L-histidinol + phosphate.
      10 A0A128H5T0 A0A128UQY8 A0A129FTQ4 A0A131N3X6 A0A182DB74 A0A1K2GFS5 G8UT89 Q5WX93 Q5X5X1 Q5ZW89