The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 43641: Eukaryotic initiation factor 4B

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
5 L7EEF1 (/ISS) Q7PLL1 (/ISS) Q7PLL3 (/ISS) Q8SYL3 (/ISS) Q9VTH9 (/ISS)
Translation initiation factor activity GO:0003743
Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.
4 L7EEF1 (/IPI) Q7PLL1 (/IPI) Q7PLL3 (/IPI) Q8SYL3 (/IPI)
Translation initiation factor activity GO:0003743
Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.
4 L7EEF1 (/ISS) Q7PLL1 (/ISS) Q7PLL3 (/ISS) Q8SYL3 (/ISS)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Translational initiation GO:0006413
The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA.
4 L7EEF1 (/IPI) Q7PLL1 (/IPI) Q7PLL3 (/IPI) Q8SYL3 (/IPI)
Translational initiation GO:0006413
The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA.
4 L7EEF1 (/ISS) Q7PLL1 (/ISS) Q7PLL3 (/ISS) Q8SYL3 (/ISS)
Cell proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
4 L7EEF1 (/IMP) Q7PLL1 (/IMP) Q7PLL3 (/IMP) Q8SYL3 (/IMP)
Positive regulation of JAK-STAT cascade GO:0046427
Any process that activates or increases the frequency, rate or extent of the JAK-STAT signaling pathway activity.
4 L7EEF1 (/IMP) Q7PLL1 (/IMP) Q7PLL3 (/IMP) Q8SYL3 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
4 L7EEF1 (/IDA) Q7PLL1 (/IDA) Q7PLL3 (/IDA) Q8SYL3 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
4 L7EEF1 (/IPI) Q7PLL1 (/IPI) Q7PLL3 (/IPI) Q8SYL3 (/IPI)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
4 L7EEF1 (/ISS) Q7PLL1 (/ISS) Q7PLL3 (/ISS) Q8SYL3 (/ISS)