The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 43225: RNA recognition motif-containing protein
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 13 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
|
11 |
F4HUQ5 (/IDA)
F4I2E4 (/IDA)
F4I321 (/IDA)
F4IIL5 (/IDA)
Q501B0 (/IDA)
Q67YS0 (/IDA)
Q8LF90 (/IDA)
Q9H0Z9 (/IDA)
Q9LES2 (/IDA)
Q9LKA4 (/IDA)
(1 more) |
|
MRNA 3'-UTR binding GO:0003730
Interacting selectively and non-covalently with the 3' untranslated region of an mRNA molecule.
|
6 | Q5ZMA3 (/ISS) Q6GQD3 (/ISS) Q6P8A7 (/ISS) Q76LC6 (/ISS) Q9BX46 (/ISS) Q9I8B3 (/ISS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
4 | H2L051 (/IPI) O45189 (/IPI) Q9LES2 (/IPI) Q9SHZ6 (/IPI) |
|
MRNA 3'-UTR binding GO:0003730
Interacting selectively and non-covalently with the 3' untranslated region of an mRNA molecule.
|
2 | D3Z4I3 (/IDA) Q9H0Z9 (/IDA) |
|
AU-rich element binding GO:0017091
Interacting selectively and non-covalently with a region of RNA containing frequent adenine and uridine bases.
|
2 | F4IIL5 (/IDA) Q9LES2 (/IDA) |
|
Pre-mRNA binding GO:0036002
Interacting selectively and non-covalently with pre-messenger RNA (pre-mRNA), an intermediate molecule between DNA and protein that may contain introns and, at least in part, encodes one or more proteins. Introns are removed from pre-mRNA to form a mRNA molecule.
|
2 | H2L051 (/IPI) O45189 (/IPI) |
|
Pre-mRNA intronic binding GO:0097157
Interacting selectively and non-covalently with an intronic sequence of a pre-messenger RNA (pre-mRNA).
|
2 | H2L051 (/IPI) O45189 (/IPI) |
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
1 | Q9H0Z9 (/IDA) |
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
1 | Q62176 (/ISO) |
|
Single-stranded RNA binding GO:0003727
Interacting selectively and non-covalently with single-stranded RNA.
|
1 | O45189 (/IDA) |
|
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
|
1 | Q62176 (/IMP) |
|
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
|
1 | Q62176 (/ISO) |
|
MRNA 3'-UTR binding GO:0003730
Interacting selectively and non-covalently with the 3' untranslated region of an mRNA molecule.
|
1 | Q62176 (/ISO) |
There are 39 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Regulation of mRNA stability GO:0043488
Any process that modulates the propensity of mRNA molecules to degradation. Includes processes that both stabilize and destabilize mRNAs.
|
6 | Q5ZMA3 (/ISS) Q6GQD3 (/ISS) Q6P8A7 (/ISS) Q76LC6 (/ISS) Q9BX46 (/ISS) Q9I8B3 (/ISS) |
|
Regulation of myotube differentiation GO:0010830
Any process that modulates the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
|
5 | Q5ZMA3 (/ISS) Q6P8A7 (/ISS) Q76LC6 (/ISS) Q9BX46 (/ISS) Q9I8B3 (/ISS) |
|
Somitogenesis GO:0001756
The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.
|
4 | E9QCG4 (/IMP) F1Q8E8 (/IMP) Q29RC2 (/IMP) Q76LC6 (/IMP) |
|
Heart looping GO:0001947
The tube morphogenesis process in which the primitive heart tube loops asymmetrically. This looping brings the primitive heart chambers into alignment preceding their future integration. Heart looping begins with dextral-looping and ends when the main regional divisions of the mature heart and primordium of the great arterial trunks become established preceeding septation.
|
4 | E9QCG4 (/IMP) F1Q8E8 (/IMP) Q29RC2 (/IMP) Q76LC6 (/IMP) |
|
Atrial cardiac muscle tissue development GO:0003228
The process whose specific outcome is the progression of cardiac muscle of the atrium over time, from its formation to the mature structure.
|
4 | E9QCG4 (/IMP) F1Q8E8 (/IMP) Q29RC2 (/IMP) Q76LC6 (/IMP) |
|
MRNA processing GO:0006397
Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.
|
4 | E9QCG4 (/IMP) F1Q8E8 (/IMP) Q29RC2 (/IMP) Q76LC6 (/IMP) |
|
Skeletal muscle tissue development GO:0007519
The developmental sequence of events leading to the formation of adult skeletal muscle tissue. The main events are: the fusion of myoblasts to form myotubes that increase in size by further fusion to them of myoblasts, the formation of myofibrils within their cytoplasm and the establishment of functional neuromuscular junctions with motor neurons. At this stage they can be regarded as mature muscle fibers.
|
4 | E9QCG4 (/IMP) F1Q8E8 (/IMP) Q29RC2 (/IMP) Q76LC6 (/IMP) |
|
Embryonic neurocranium morphogenesis GO:0048702
The process in which the anatomical structures of the neurocranium are generated and organized during the embryonic phase. The neurocranium is the portion of the vertebrate skull surrounding the brain.
|
4 | E9QCG4 (/IMP) F1Q8E8 (/IMP) Q29RC2 (/IMP) Q76LC6 (/IMP) |
|
Cardiovascular system development GO:0072358
The process whose specific outcome is the progression of the cardiovascular system over time, from its formation to the mature structure. The cardiovascular system is the anatomical system that has as its parts the heart and blood vessels.
|
4 | E9QCG4 (/IGI) F1Q8E8 (/IGI) Q29RC2 (/IGI) Q76LC6 (/IGI) |
|
Ventricular cardiac muscle tissue development GO:0003229
The process whose specific outcome is the progression of ventricular cardiac muscle over time, from its formation to the mature structure.
|
3 | E9QCG4 (/IMP) F1Q8E8 (/IMP) Q29RC2 (/IMP) |
|
Defense response GO:0006952
Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
|
3 | O80678 (/IMP) Q9LES2 (/IMP) Q9LKA4 (/IMP) |
|
Cell death GO:0008219
Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538).
|
3 | O80678 (/IMP) Q9LES2 (/IMP) Q9LKA4 (/IMP) |
|
Ethylene biosynthetic process GO:0009693
The chemical reactions and pathways resulting in the formation of ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator.
|
3 | O80678 (/IMP) Q9LES2 (/IMP) Q9LKA4 (/IMP) |
|
Leaf senescence GO:0010150
The process that occurs in a leaf near the end of its active life that is associated with the dismantling of cell components and membranes, loss of functional chloroplasts, and an overall decline in metabolism.
|
3 | O80678 (/IMP) Q9LES2 (/IMP) Q9LKA4 (/IMP) |
|
Alternative mRNA splicing, via spliceosome GO:0000380
The process of generating multiple mRNA molecules from a given set of exons by differential use of exons from the primary transcript(s) to form multiple mature mRNAs that vary in their exon composition.
|
2 | H2L051 (/IMP) O45189 (/IMP) |
|
Regulation of alternative mRNA splicing, via spliceosome GO:0000381
Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs.
|
2 | H2L051 (/IMP) O45189 (/IMP) |
|
Regulation of myotube differentiation GO:0010830
Any process that modulates the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
|
2 | D3Z4I3 (/IMP) Q6GQD3 (/IMP) |
|
Regulation of actin cytoskeleton organization GO:0032956
Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
|
2 | H2L051 (/IGI) O45189 (/IGI) |
|
Regulation of locomotion GO:0040012
Any process that modulates the frequency, rate or extent of locomotion of a cell or organism.
|
2 | H2L051 (/IGI) O45189 (/IGI) |
|
MRNA stabilization GO:0048255
Prevention of degradation of mRNA molecules. In the absence of compensating changes in other processes, the slowing of mRNA degradation can result in an overall increase in the population of active mRNA molecules.
|
2 | F4IIL5 (/NAS) Q9LES2 (/NAS) |
|
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977
A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage and resulting in the stopping or reduction in rate of the cell cycle.
|
1 | Q9H0Z9 (/IDA) |
|
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977
A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage and resulting in the stopping or reduction in rate of the cell cycle.
|
1 | Q62176 (/ISO) |
|
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator GO:0006978
A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, resulting in the induction of the transcription of p21 (also known as WAF1, CIP1 and SDI1) or any equivalent protein, in response to the detection of DNA damage.
|
1 | Q9H0Z9 (/IDA) |
|
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator GO:0006978
A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, resulting in the induction of the transcription of p21 (also known as WAF1, CIP1 and SDI1) or any equivalent protein, in response to the detection of DNA damage.
|
1 | Q62176 (/ISO) |
|
Cell cycle arrest GO:0007050
A regulatory process that halts progression through the cell cycle during one of the normal phases (G1, S, G2, M).
|
1 | Q9H0Z9 (/IDA) |
|
Negative regulation of cell proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
|
1 | Q9H0Z9 (/IDA) |
|
Negative regulation of cell proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
|
1 | Q62176 (/ISO) |
|
Response to water deprivation GO:0009414
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.
|
1 | Q9M1S3 (/IMP) |
|
Response to salt stress GO:0009651
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
|
1 | Q9M1S3 (/IMP) |
|
Response to abscisic acid GO:0009737
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.
|
1 | Q9M1S3 (/IEP) |
|
Abscisic acid-activated signaling pathway GO:0009738
A series of molecular signals generated by the binding of the plant hormone abscisic acid (ABA) to a receptor, and ending with modulation of a cellular process, e.g. transcription.
|
1 | Q9LES2 (/TAS) |
|
Regulation of seed germination GO:0010029
Any process that modulates the frequency, rate or extent of seed germination.
|
1 | Q9M1S3 (/IMP) |
|
Regulation of myotube differentiation GO:0010830
Any process that modulates the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
|
1 | Q62176 (/IDA) |
|
Regulation of RNA splicing GO:0043484
Any process that modulates the frequency, rate or extent of RNA splicing, the process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.
|
1 | Q9H0Z9 (/IDA) |
|
Regulation of RNA splicing GO:0043484
Any process that modulates the frequency, rate or extent of RNA splicing, the process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.
|
1 | Q62176 (/ISO) |
|
Regulation of mRNA stability GO:0043488
Any process that modulates the propensity of mRNA molecules to degradation. Includes processes that both stabilize and destabilize mRNAs.
|
1 | D3Z4I3 (/IMP) |
|
Regulation of sarcomere organization GO:0060297
Any process that modulates the rate, frequency or extent myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
|
1 | Q76LC6 (/IMP) |
|
3'-UTR-mediated mRNA stabilization GO:0070935
An mRNA stabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA.
|
1 | Q9H0Z9 (/IDA) |
|
3'-UTR-mediated mRNA stabilization GO:0070935
An mRNA stabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA.
|
1 | Q62176 (/ISO) |
There are 9 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
6 | F4IIL5 (/IDA) O80678 (/IDA) Q9H0Z9 (/IDA) Q9LES2 (/IDA) Q9LKA4 (/IDA) Q9M1S3 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
4 | A8KAI7 (/IDA) Q9BX46 (/IDA) Q9H0Z9 (/IDA) Q9LES2 (/IDA) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
2 | A8KAI7 (/IDA) Q9BX46 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | D3Z4I3 (/ISO) Q62176 (/ISO) |
|
Nuclear speck GO:0016607
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
|
2 | H2L051 (/IDA) O45189 (/IDA) |
|
Intracellular ribonucleoprotein complex GO:0030529
An intracellular macromolecular complex containing both protein and RNA molecules.
|
2 | H2L051 (/IPI) O45189 (/IPI) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q62176 (/ISO) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | D3Z4I3 (/ISO) |
|
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
|
1 | Q9LKA4 (/IDA) |
