The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 42743: Dead end homolog 1 (Zebrafish)

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
AU-rich element binding GO:0017091
Interacting selectively and non-covalently with a region of RNA containing frequent adenine and uridine bases.
4 F1RGE0 (/ISS) Q6DCB7 (/ISS) Q6VY05 (/ISS) Q7T1H5 (/ISS)
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
2 F1RGE0 (/IDA) Q7T1H5 (/IDA)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
1 Q7T1H5 (/IPI)
MRNA 3'-UTR binding GO:0003730
Interacting selectively and non-covalently with the 3' untranslated region of an mRNA molecule.
1 Q7T1H5 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q6VY05 (/IPI)
AU-rich element binding GO:0017091
Interacting selectively and non-covalently with a region of RNA containing frequent adenine and uridine bases.
1 Q8IYX4 (/IDA)
AU-rich element binding GO:0017091
Interacting selectively and non-covalently with a region of RNA containing frequent adenine and uridine bases.
1 Q6VY05 (/ISO)

There are 11 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Negative regulation of gene silencing by miRNA GO:0060965
Any process that decreases the rate, frequency, or extent of the downregulation of gene expression through the action of microRNAs (miRNAs), endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: mRNA cleavage or translational repression.
4 F1RGE0 (/ISS) Q6DCB7 (/ISS) Q6VY05 (/ISS) Q7T1H5 (/ISS)
Germ cell development GO:0007281
The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism.
2 Q6VY05 (/IMP) Q7T1H5 (/IMP)
Germ cell development GO:0007281
The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism.
1 F1RGE0 (/ISS)
Germ cell migration GO:0008354
The orderly movement of a cell specialized to produce haploid gametes through the embryo from its site of production to the place where the gonads will form.
1 Q7T1H5 (/IMP)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 Q7T1H5 (/IDA)
MRNA stabilization GO:0048255
Prevention of degradation of mRNA molecules. In the absence of compensating changes in other processes, the slowing of mRNA degradation can result in an overall increase in the population of active mRNA molecules.
1 Q7T1H5 (/IMP)
Heart contraction GO:0060047
The multicellular organismal process in which the heart decreases in volume in a characteristic way to propel blood through the body.
1 Q7T1H5 (/IMP)
Negative regulation of gene silencing by miRNA GO:0060965
Any process that decreases the rate, frequency, or extent of the downregulation of gene expression through the action of microRNAs (miRNAs), endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: mRNA cleavage or translational repression.
1 Q8IYX4 (/IDA)
Negative regulation of gene silencing by miRNA GO:0060965
Any process that decreases the rate, frequency, or extent of the downregulation of gene expression through the action of microRNAs (miRNAs), endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: mRNA cleavage or translational repression.
1 Q6VY05 (/ISO)
Regulation of cell motility GO:2000145
Any process that modulates the frequency, rate or extent of cell motility.
1 Q7T1H5 (/IGI)
Regulation of cell motility GO:2000145
Any process that modulates the frequency, rate or extent of cell motility.
1 Q7T1H5 (/IMP)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 Q6DCB7 (/ISS) Q6VY05 (/ISS) Q7T1H5 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 F1RGE0 (/IDA) Q6VY05 (/IDA) Q8IYX4 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 Q6DCB7 (/ISS) Q6VY05 (/ISS) Q7T1H5 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 F1RGE0 (/IDA) Q8IYX4 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q6VY05 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q6VY05 (/ISO)
Germ cell nucleus GO:0043073
The nucleus of a germ cell, a reproductive cell in multicellular organisms.
1 Q7T1H5 (/IDA)
P granule GO:0043186
A small cytoplasmic, non-membranous RNA/protein complex aggregates in the primordial germ cells of many higher eukaryotes.
1 Q7T1H5 (/IDA)
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