The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 41717: TAR DNA-binding protein-43 homolog, isoform A

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Single-stranded DNA binding GO:0003697
Interacting selectively and non-covalently with single-stranded DNA.
3 O97468 (/IDA) Q8SXP8 (/IDA) Q9W1I0 (/IDA)
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
3 O97468 (/ISS) Q8SXP8 (/ISS) Q9W1I0 (/ISS)
GU repeat RNA binding GO:1990605
Interacting selectively and non-covalently with an RNA molecule containing GU repeats.
3 O97468 (/IDA) Q8SXP8 (/IDA) Q9W1I0 (/IDA)

There are 24 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Neuromuscular synaptic transmission GO:0007274
The process of communication from a neuron to a muscle, across a synapse.
3 O97468 (/IMP) Q8SXP8 (/IMP) Q9W1I0 (/IMP)
Synapse assembly GO:0007416
The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional).
3 O97468 (/IMP) Q8SXP8 (/IMP) Q9W1I0 (/IMP)
Central nervous system development GO:0007417
The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
3 O97468 (/IMP) Q8SXP8 (/IMP) Q9W1I0 (/IMP)
Neuromuscular junction development GO:0007528
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction.
3 O97468 (/IMP) Q8SXP8 (/IMP) Q9W1I0 (/IMP)
Locomotory behavior GO:0007626
The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.
3 O97468 (/IMP) Q8SXP8 (/IMP) Q9W1I0 (/IMP)
Adult walking behavior GO:0007628
The behavior of an adult relating to the progression of that organism along the ground by the process of lifting and setting down each leg.
3 O97468 (/IMP) Q8SXP8 (/IMP) Q9W1I0 (/IMP)
Adult locomotory behavior GO:0008344
Locomotory behavior in a fully developed and mature organism.
3 O97468 (/IMP) Q8SXP8 (/IMP) Q9W1I0 (/IMP)
Larval locomotory behavior GO:0008345
Locomotory behavior in a larval (immature) organism.
3 O97468 (/IMP) Q8SXP8 (/IMP) Q9W1I0 (/IMP)
Regulation of synaptic growth at neuromuscular junction GO:0008582
Any process that modulates the frequency, rate or extent of synaptic growth at neuromuscular junctions.
3 O97468 (/IMP) Q8SXP8 (/IMP) Q9W1I0 (/IMP)
Regulation of glucose metabolic process GO:0010906
Any process that modulates the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose.
3 O97468 (/IMP) Q8SXP8 (/IMP) Q9W1I0 (/IMP)
Negative regulation of RNA splicing GO:0033119
Any process that stops, prevents, or reduces the frequency, rate or extent of RNA splicing.
3 O97468 (/IDA) Q8SXP8 (/IDA) Q9W1I0 (/IDA)
Regulation of intracellular steroid hormone receptor signaling pathway GO:0033143
Any process that modulates the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway.
3 O97468 (/IGI) Q8SXP8 (/IGI) Q9W1I0 (/IGI)
Regulation of intracellular steroid hormone receptor signaling pathway GO:0033143
Any process that modulates the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway.
3 O97468 (/IMP) Q8SXP8 (/IMP) Q9W1I0 (/IMP)
Regulation of intracellular steroid hormone receptor signaling pathway GO:0033143
Any process that modulates the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway.
3 O97468 (/IPI) Q8SXP8 (/IPI) Q9W1I0 (/IPI)
Locomotion GO:0040011
Self-propelled movement of a cell or organism from one location to another.
3 O97468 (/IMP) Q8SXP8 (/IMP) Q9W1I0 (/IMP)
Negative regulation of neuron apoptotic process GO:0043524
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons.
3 O97468 (/IMP) Q8SXP8 (/IMP) Q9W1I0 (/IMP)
Negative regulation of synaptic growth at neuromuscular junction GO:0045886
Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic growth at neuromuscular junction.
3 O97468 (/IMP) Q8SXP8 (/IMP) Q9W1I0 (/IMP)
Neuron projection morphogenesis GO:0048812
The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites.
3 O97468 (/IMP) Q8SXP8 (/IMP) Q9W1I0 (/IMP)
Regulation of microtubule cytoskeleton organization GO:0070507
Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.
3 O97468 (/IGI) Q8SXP8 (/IGI) Q9W1I0 (/IGI)
Regulation of microtubule cytoskeleton organization GO:0070507
Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.
3 O97468 (/IMP) Q8SXP8 (/IMP) Q9W1I0 (/IMP)
Regulation of microtubule cytoskeleton organization GO:0070507
Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.
3 O97468 (/IPI) Q8SXP8 (/IPI) Q9W1I0 (/IPI)
Terminal button organization GO:0072553
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a terminal button. A terminal button is the terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters.
3 O97468 (/IMP) Q8SXP8 (/IMP) Q9W1I0 (/IMP)
Positive regulation of dendrite development GO:1900006
Any process that activates or increases the frequency, rate or extent of dendrite development.
3 O97468 (/IMP) Q8SXP8 (/IMP) Q9W1I0 (/IMP)
Regulation of terminal button organization GO:2000331
Any process that modulates the frequency, rate or extent of terminal button organization.
3 O97468 (/IMP) Q8SXP8 (/IMP) Q9W1I0 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 O97468 (/IDA) Q8SXP8 (/IDA) Q9W1I0 (/IDA)
H zone GO:0031673
A relatively pale zone traversing the center of the A band of a sarcomere, visible in relaxed muscle fibers; consists of the central portion of thick (myosin) filaments that are not overlapped by thin (actin) filaments.
3 O97468 (/IDA) Q8SXP8 (/IDA) Q9W1I0 (/IDA)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
3 O97468 (/IDA) Q8SXP8 (/IDA) Q9W1I0 (/IDA)
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