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CATH Superfamily 3.30.70.1230

Nucleotide cyclase, GGDEF domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Nucleotide cyclase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5760: Adenylate cyclase type 2

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Adenylate cyclase. [EC: 4.6.1.1]
ATP = 3',5'-cyclic AMP + diphosphate.
  • Also acts on dATP to form 3',5'-cyclic dAMP.
  • Requires pyruvate.
  • Activated by NAD(+) in presence of EC 2.4.2.31.
 123 A0A061I0F9 A0A061IB91 A0A0J9RZ56 A0A0J9RZ97 A0A0J9RZF5 A0A0K0K1K3 A0A0N8NZK8 A0A0P8XIF0 A0A0P8XIF3 A0A0P8XYM4
(113 more...)
Guanylate cyclase. [EC: 4.6.1.2]
GTP = 3',5'-cyclic GMP + diphosphate.
  • Also acts on ITP and dGTP.
 6 A0A182FFX0 A0A1J1HTL6 E0VF29 E0VG99 L9L2K4 S9XPH1