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CATH Superfamily 3.30.565.10

Histidine kinase-like ATPase, C-terminal domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Histidine kinase-like ATPase, C-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 80880: Multi-sensor hybrid histidine kinase

There are 5 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Histidine kinase. [EC: 2.7.13.3]
ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.
  • This entry has been included to accommodate those protein-histidine kinases for which the phosphorylation site has not been established (i.e. either the pros- or tele-nitrogen of histidine).
  • A number of histones can act as acceptor.
 1029 A0A010QC29 A0A011MU16 A0A011MUH6 A0A011NBN6 A0A011P5Y9 A0A017IJI5 A0A022PH72 A0A023PCA8 A0A023PF64 A0A024HIT0
(1019 more...)
Adenylate cyclase. [EC: 4.6.1.1]
ATP = 3',5'-cyclic AMP + diphosphate.
  • Also acts on dATP to form 3',5'-cyclic dAMP.
  • Requires pyruvate.
  • Activated by NAD(+) in presence of EC 2.4.2.31.
 1 W2UP09
Arginine kinase. [EC: 2.7.3.3]
ATP + L-arginine = ADP + N(omega)-phospho-L-arginine.
    		 1 F8GSQ2
    Protein-glutamate methylesterase. [EC: 3.1.1.61]
    Protein L-glutamate O(5)-methyl ester + H(2)O = protein L-glutamate + methanol.
    • Hydrolyzes the products of EC 2.1.1.77, EC 2.1.1.78, EC 2.1.1.80 and EC 2.1.1.100.
    		 1 A0ZC88
    Hydroxypyruvate isomerase. [EC: 5.3.1.22]
    Hydroxypyruvate = 2-hydroxy-3-oxopropanoate.
      		 1 G8Q1U4