The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"SH2 domain
".
FunFam 419: Non-specific protein-tyrosine kinase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein tyrosine kinase activity GO:0004713
Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate.
|
1 | G5EE56 (/IDA) |
|
Non-membrane spanning protein tyrosine kinase activity GO:0004715
Catalysis of the reaction: ATP + protein L-tyrosine = ADP + protein L-tyrosine phosphate by a non-membrane spanning protein.
|
1 | G5EE56 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | G5EE56 (/IPI) |
|
Netrin receptor binding GO:1990890
Interacting selectively and non-covalently with a netrin receptor.
|
1 | G5EE56 (/IPI) |
There are 16 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Establishment of mitotic spindle orientation GO:0000132
A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures.
|
1 | G5EE56 (/IGI) |
|
Establishment of mitotic spindle orientation GO:0000132
A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures.
|
1 | G5EE56 (/IMP) |
|
Endodermal cell fate specification GO:0001714
The cell fate determination process that results in a cell becoming capable of differentiating autonomously into an endoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
|
1 | G5EE56 (/IGI) |
|
Anterior/posterior axis specification, embryo GO:0008595
The specification of the anterior/posterior axis of the embryo by the products of genes expressed maternally and genes expressed in the zygote.
|
1 | G5EE56 (/IMP) |
|
Embryo development ending in birth or egg hatching GO:0009792
The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell.
|
1 | G5EE56 (/IMP) |
|
Gonad morphogenesis GO:0035262
The process in which the anatomical structures of the gonads are generated and organized. A gonad is an animal organ producing gametes, e.g. the testes or the ovary in mammals.
|
1 | G5EE56 (/IGI) |
|
Gonad morphogenesis GO:0035262
The process in which the anatomical structures of the gonads are generated and organized. A gonad is an animal organ producing gametes, e.g. the testes or the ovary in mammals.
|
1 | G5EE56 (/IMP) |
|
Peptidyl-tyrosine autophosphorylation GO:0038083
The phosphorylation by a protein of one or more of its own tyrosine amino acid residues, or a tyrosine residue on an identical protein.
|
1 | G5EE56 (/IDA) |
|
Positive regulation of locomotion GO:0040017
Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism.
|
1 | G5EE56 (/IGI) |
|
Positive regulation of embryonic development GO:0040019
Any process that activates or increases the frequency, rate or extent of embryonic development.
|
1 | G5EE56 (/IMP) |
|
Protein autophosphorylation GO:0046777
The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation).
|
1 | G5EE56 (/IDA) |
|
Embryonic digestive tract morphogenesis GO:0048557
The process in which the anatomical structures of the digestive tract are generated and organized during embryonic development. The digestive tract is the anatomical structure through which food passes and is processed.
|
1 | G5EE56 (/IGI) |
|
Embryonic digestive tract morphogenesis GO:0048557
The process in which the anatomical structures of the digestive tract are generated and organized during embryonic development. The digestive tract is the anatomical structure through which food passes and is processed.
|
1 | G5EE56 (/IMP) |
|
Positive regulation of peptidyl-tyrosine phosphorylation GO:0050731
Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.
|
1 | G5EE56 (/IMP) |
|
Left/right axis specification GO:0070986
The establishment, maintenance and elaboration of the left/right axis. The left/right axis is defined by a line that runs orthogonal to both the anterior/posterior and dorsal/ventral axes. Each side is defined from the viewpoint of the organism rather of the observer (as per anatomical axes).
|
1 | G5EE56 (/IGI) |
|
Commissural neuron axon guidance GO:0071679
The process in which the migration of an axon growth cone of a commissural neuron is directed to its target in the brain in response to a combination of attractive and repulsive cues.
|
1 | G5EE56 (/IGI) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Phagocytic cup GO:0001891
An invagination of the cell membrane formed by an actin dependent process during phagocytosis. Following internalization it is converted into a phagosome.
|
1 | G5EE56 (/IDA) |
|
Contractile fiber GO:0043292
Fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle.
|
1 | G5EE56 (/IDA) |