The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"SH2 domain
".
FunFam 415: Non-specific protein-tyrosine kinase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
|
1 | Q22146 (/IDA) |
|
Beta-catenin binding GO:0008013
Interacting selectively and non-covalently with the beta subunit of the catenin complex.
|
1 | Q22146 (/IPI) |
There are 11 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Positive regulation of cell proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
1 | Q22146 (/IMP) |
|
Embryonic body morphogenesis GO:0010172
The process in which the anatomical structures of the embryonic soma are generated and organized.
|
1 | Q22146 (/IMP) |
|
Single organismal cell-cell adhesion GO:0016337
The attachment of one cell to another cell via adhesion molecules, where both cells are part of the same organism.
|
1 | Q22146 (/IMP) |
|
Regulation of protein localization GO:0032880
Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.
|
1 | Q22146 (/IMP) |
|
Negative regulation of catenin import into nucleus GO:0035414
Any process that decreases the rate, frequency or extent of the directed movement of a catenin protein from the cytoplasm into the nucleus.
|
1 | Q22146 (/IMP) |
|
Wnt signaling pathway involved in digestive tract morphogenesis GO:0044333
The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell contributing to the generation and the organization of the digestive tract.
|
1 | Q22146 (/IGI) |
|
Regulation of epidermal cell differentiation GO:0045604
Any process that modulates the frequency, rate or extent of epidermal cell differentiation.
|
1 | Q22146 (/IMP) |
|
Protein autophosphorylation GO:0046777
The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation).
|
1 | Q22146 (/IDA) |
|
Negative regulation of cell division GO:0051782
Any process that stops, prevents, or reduces the frequency, rate or extent of cell division.
|
1 | Q22146 (/IGI) |
|
Negative regulation of cell division GO:0051782
Any process that stops, prevents, or reduces the frequency, rate or extent of cell division.
|
1 | Q22146 (/IMP) |
|
Negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis GO:2000057
Any process that stops, prevents, or reduces the frequency, rate or extent of Wnt signaling pathway involved in digestive tract morphogenesis.
|
1 | Q22146 (/IGI) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q22146 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q22146 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q22146 (/IDA) |
|
Cell-cell junction GO:0005911
A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals.
|
1 | Q22146 (/IDA) |
