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CATH Superfamily 3.30.43.10

Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 12100: D-Arabinono-1,4-lactone oxidase (Eurofung)

There are 5 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
L-gulonolactone oxidase. [EC: 1.1.3.8]
L-gulono-1,4-lactone + O(2) = L-ascorbate + H(2)O(2).
  • The product spontaneously isomerizes to L-ascorbate.
  • While most higher animals can synthesize ascorbic acid, primates and guinea pigs cannot.
 39 A0A059MT46 A0A0B8NPN9 A0A0B9AK84 A0A0G3V0S0 A0A0J0YI73 A0A0N0ML90 A0A0N0N256 A0A0N1H630 A0A0N1NL18 A0A1C6WCV7
(29 more...)
Alditol oxidase. [EC: 1.1.3.41]
An alditol + O(2) = an aldose + H(2)O(2).
  • While xylitol (five carbons) and sorbitol (6 carbons) are the preferred substrates, other alditols, including L-threitol (four carbons), D-arabinitol (five carbons), D-galactitol (six carbons) and D-mannitol (six carbons) can also act as substrates, but more slowly.
 33 A0A045IUM0 A0A0C7DUZ5 A0A0E8TK92 A0A0F6FLL2 A0A0F6J509 A0A0G4DZU1 A0A0H3LGE9 A0A0H3P3L4 A0A0H5P6T6 A0A0T8G5S1
(23 more...)
D-arabinono-1,4-lactone oxidase. [EC: 1.1.3.37]
D-arabinono-1,4-lactone + O(2) = dehydro-D-arabinono-1,4-lactone + H(2)O(2).
    		 29 A0A0B0DTV2 A0A0F4Z0X7 A0A0L1HIV2 A0A0P4UA74 A0A1H6PWT8 B3LLH0 B8M2X2 B9WMY6 C4YN06 C5PAG4
    (19 more...)
    L-galactonolactone dehydrogenase. [EC: 1.3.2.3]
    L-galactono-1,4-lactone + 4 ferricytochrome c = L-dehydroascorbate + 4 ferrocytochrome c + 4 H(+).
    • Catalyzes the final step in the biosynthesis of L-ascorbic acid in higher plants and in nearly all higher animals with the exception of primates and some birds.
    • Very specific for its substrate L-galactono-1,4-lactone as D-galactono-gamma-lactone, D-gulono-gamma-lactone, L-gulono-gamma- lactone, D-erythronic-gamma-lactone, D-xylonic-gamma-lactone, L-mannono-gamma-lactone, D-galactonate, D-glucuronate and D-gluconate are not substrates.
    • FAD, NAD(+), NADP(+) and O(2) (cf. EC 1.3.3.12) cannot act as electron acceptor.
    		 20 A0A078GCD4 A0A0H4LTI6 A0A159BQ96 A0A178VN92 B6ZL96 C0LQA3 C0LVB5 C3S7Q7 K8Z718 O47881
    (10 more...)
    UDP-N-acetylmuramate dehydrogenase. [EC: 1.3.1.98]
    UDP-N-acetyl-alpha-D-muramate + NADP(+) = UDP-N-acetyl-3- O-(1-carboxyvinyl)-alpha-D-glucosamine + NADPH.
    • NADH can to a lesser extent replace NADPH.
    • Formerly EC 1.1.1.158.
    		 2 A0A0L1HIV2 A0A0P4UA74
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