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CATH Superfamily 3.20.20.70

Aldolase class I

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Aldolase class I
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 97812: Radical SAM protein

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
7-carboxy-7-deazaguanine synthase. [EC: 4.3.99.3]
6-carboxy-5,6,7,8-tetrahydropterin = 7-carboxy-7-carbaguanine + NH(3).
  • The enzyme is a member of the superfamily of S-adenosyl-L-methionine- dependent radical (radical AdoMet) enzymes.
  • Binds a [4Fe-4S] cluster that is coordinated by 3 cysteines and an exchangeable S-adenosyl-L-methionine molecule.
  • The S-adenosyl-L-methionine is catalytic as it is regenerated at the end of the reaction.
  • The reaction is part of the biosynthesis pathway of queuosine.
 22 A0A059I311 A0A0B6UNV7 A0A0D7VCB0 A0A0E1ZLV8 A0A0E2UW40 A0A0H3PAN0 A0A0M4TRJ9 A0A0W8KQ61 A0A0W8KYE6 A0A0W8L8Y0
(12 more...)