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CATH Superfamily 3.20.20.70

Aldolase class I

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Aldolase class I
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 94996: 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deox...

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
2-dehydro-3-deoxy-phosphogluconate aldolase. [EC: 4.1.2.14]
2-dehydro-3-deoxy-6-phosphate-D-gluconate = pyruvate + D-glyceraldehyde 3-phosphate.
  • The enzyme shows no activity with 2-dehydro-3-deoxy-6-phosphate-D- galactonate (cf. EC 4.1.2.55).
  • Also acts on 2-oxobutanoate.
 18 A0A085PGU3 A0A085T5R5 A0A085THR4 A0A0E4CCN1 A0A0H3ANE6 A0A0H3QCQ5 A0A0H6T2F5 A0A0K9UMA6 A0A0X1L4Q6 A0A1D8SEJ3
(8 more...)
4-hydroxy-2-oxoglutarate aldolase. [EC: 4.1.3.16]
4-hydroxy-2-oxoglutarate = pyruvate + glyoxylate.
  • The enzymes from rat liver and bovine liver act on both enantiomers of 4-hydroxy-2-oxoglutarate.
  • Formerly EC 4.1.2.1 and EC 4.1.2.31.
 16 A0A085THR4 A0A0E4CCN1 A0A0H3ANE6 A0A0H3QCQ5 A0A0H6T2F5 A0A0K9UMA6 A0A0X1L4Q6 A0A1D8SEJ3 C2HRA4 C3LQP1
(6 more...)