The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Aldolase class I
".
FunFam 74818: Thiamine biosynthetic bifunctional enzyme
There are 2 EC terms in this cluster
Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
EC Term | Annotations | Evidence |
---|---|---|
Hydroxyethylthiazole kinase.
[EC: 2.7.1.50]
ATP + 4-methyl-5-(2-hydroxyethyl)thiazole = ADP + 4-methyl-5- (2-phosphonooxyethyl)thiazole.
|
10 | A0A0L8VGV0 A6ZW41 B3LKL6 C7GN41 C8ZIG5 E7KVB7 E7QLM6 G2WNX1 N1NW91 P41835 |
Thiamine phosphate synthase.
[EC: 2.5.1.3]
(1) 4-amino-2-methyl-5-diphosphomethylpyrimidine + 2-((2R,5Z)-2-carboxy- 4-methylthiazol-5(2H)-ylidene)ethyl phosphate = diphosphate + thiamine phosphate + CO(2). (2) 4-amino-2-methyl-5-diphosphomethylpyrimidine + 2-(2-carboxy-4- methylthiazol-5-yl)ethyl phosphate = diphosphate + thiamine phosphate + CO(2). (3) 4-amino-2-methyl-5-diphosphomethylpyrimidine + 4-methyl-5- (2-phosphono-oxyethyl)thiazole = diphosphate + thiamine phosphate.
|
10 | A0A0L8VGV0 A6ZW41 B3LKL6 C7GN41 C8ZIG5 E7KVB7 E7QLM6 G2WNX1 N1NW91 P41835 |