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CATH Superfamily 3.20.20.70

Aldolase class I

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Aldolase class I
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 120831: 3-dehydroquinate synthase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
3-dehydroquinate synthase II. [EC: 1.4.1.24]
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H(2)O + NAD(+) = 3-dehydroquinate + NH(3) + NADH.
  • The enzyme, which was isolated from the archaeon Methanocaldococcus jannaschii, plays a key role in an alternative pathway for the biosynthesis of 3-dehydroquinate (DHQ), an intermediate of the canonical pathway for the biosynthesis of aromatic amino acids.
  • The enzyme catalyzes a two-step reaction - an oxidative deamination, followed by cyclization.
 74 A0A0E3H960 A0A0E3KRF0 A0A0E3KSI9 A0A0E3KW43 A0A0E3L048 A0A0E3LBZ9 A0A0E3LRH5 A0A0E3LV87 A0A0E3P0M2 A0A0E3P9P8
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