The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Aldolase class I
".
FunFam 120571: Probable thiamine biosynthetic bifunctional enzyme...
There are 3 EC terms in this cluster
Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
EC Term | Annotations | Evidence |
---|---|---|
Thiamine phosphate synthase.
[EC: 2.5.1.3]
(1) 4-amino-2-methyl-5-diphosphomethylpyrimidine + 2-((2R,5Z)-2-carboxy- 4-methylthiazol-5(2H)-ylidene)ethyl phosphate = diphosphate + thiamine phosphate + CO(2). (2) 4-amino-2-methyl-5-diphosphomethylpyrimidine + 2-(2-carboxy-4- methylthiazol-5-yl)ethyl phosphate = diphosphate + thiamine phosphate + CO(2). (3) 4-amino-2-methyl-5-diphosphomethylpyrimidine + 4-methyl-5- (2-phosphono-oxyethyl)thiazole = diphosphate + thiamine phosphate.
|
9 | A0A178W9W3 A5UUL3 A7NRF7 B9SXF8 C4XIJ2 K6FFP4 O48881 Q2QWK9 Q5M731 |
Hydroxymethylpyrimidine kinase.
[EC: 2.7.1.49]
ATP + 4-amino-5-hydroxymethyl-2-methylpyrimidine = ADP + 4-amino-2- methyl-5-(phosphomethyl)pyrimidine.
|
8 | A0A0B2PUS5 A0A0B2SKQ5 A0A0R0H690 A0A178W9W3 I1KUN6 O48881 Q2QWK9 Q5M731 |
Phosphooxymethylpyrimidine kinase.
[EC: 2.7.4.7]
ATP + 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine = ADP + 4-amino-2- methyl-5-(diphosphooxymethyl)pyrimidine.
|
5 | A0A0B2PUS5 A0A0B2SKQ5 A0A0R0H690 B9SXF8 I1KUN6 |