The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Aldolase class I
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 119773: tRNA-dihydrouridine synthase A

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
TRNA-dihydrouridine(20) synthase (NAD(P)(+)). [EC: 1.3.1.91]
5,6-dihydrouracil(20) in tRNA + NAD(P)(+) = uracil(20) in tRNA + NAD(P)H.
  • The enzyme specifically modifies uracil(20) in tRNA.
4643 A0A009F160 A0A009G646 A0A009HHY6 A0A009HLA9 A0A009HTW7 A0A009JIE4 A0A009JP81 A0A009LF51 A0A009ME04 A0A009Q9U9
(4633 more...)
TRNA-dihydrouridine(47) synthase (NAD(P)(+)). [EC: 1.3.1.89]
5,6-dihydrouracil(47) in tRNA + NAD(P)(+) = uracil(47) in tRNA + NAD(P)H.
  • The enzyme specifically modifies uracil(47) in tRNA.
15 A0A024X8Y2 A0A0J9SE65 A0A0J9TZZ4 A0A0J9VKH2 A0A1A8VY94 A0A1C3KBL2 A0A1C3KQJ3 A0A1D3U7R5 A0A1G4GV90 A0A1J1H7J1
(5 more...)
1-(5-phosphoribosyl)-5- ((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase. [EC: 5.3.1.16]
1-(5-phospho-beta-D-ribosyl)-5-((5-phospho-beta-D- ribosylamino)methylideneamino)imidazole-4-carboxamide = 5-((5-phospho-1- deoxy-D-ribulos-1-ylamino)methylideneamino)-1-(5-phospho-beta-D- ribosyl)imidazole-4-carboxamide.
  • Involved in histidine biosynthesis.
1 L0AYE6
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