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CATH Superfamily 3.20.20.70

Aldolase class I

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Aldolase class I
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 119615: Pyridoxine biosynthesis protein PDX1

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Pyridoxal 5'-phosphate synthase (glutamine hydrolyzing). [EC: 4.3.3.6]
D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine = pyridoxal 5'-phosphate + L-glutamate + 3 H(2)O + phosphate.
  • The ammonia is provided by the glutaminase subunit and channeled to the active site of the lyase subunit by a 100 A tunnel.
  • The enzyme can also use ribulose 5-phosphate and dihydroxyacetone phosphate.
  • The enzyme complex is found in aerobic bacteria, archeae, fungi and plants.
 9106 A0A010Q557 A0A010Q557 A0A010Z1K8 A0A010Z1K8 A0A011SGZ5 A0A011SGZ5 A0A011TYA0 A0A011TYA0 A0A014LQ75 A0A014LQ75
(9096 more...)
Phosphoinositide phospholipase C. [EC: 3.1.4.11]
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol.
  • These enzymes form some of the cyclic phosphate Ins(cyclic 1,2)P(4,5)P(2) as well as Ins(1,4,5)P(3).
  • They show activity toward phosphatidylinositol, i.e., the activity of EC 4.6.1.13 in vitro at high calcium concentration.
 2 I6YMA7 I6YMA7
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