The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Aldolase class I
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 118865: Bifunctional 3-deoxy-7-phosphoheptulonate synthase...

There are 5 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
3-deoxy-7-phosphoheptulonate synthase. [EC: 2.5.1.54]
Phosphoenolpyruvate + D-erythrose 4-phosphate + H(2)O = 3-deoxy-D- arabino-hept-2-ulosonate 7-phosphate + phosphate.
  • Formerly EC 4.1.2.15.
590 A0A023DDH8 A0A023DDH8 A0A023P7P4 A0A023P7P4 A0A023PCK4 A0A023PCK4 A0A063CKM5 A0A063CKM5 A0A063XAI0 A0A063XAI0
(580 more...)
Chorismate mutase. [EC: 5.4.99.5]
Chorismate = prephenate.
    560 A0A023DDH8 A0A023DDH8 A0A023P7P4 A0A023P7P4 A0A063CKM5 A0A063CKM5 A0A063XAI0 A0A063XAI0 A0A063YQ62 A0A063YQ62
    (550 more...)
    3-phosphoshikimate 1-carboxyvinyltransferase. [EC: 2.5.1.19]
    Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O- (1-carboxyvinyl)-3-phosphoshikimate.
      4 A0A0A2SK17 A0A0A2SK17 M5QVG2 M5QVG2
      Prephenate dehydratase. [EC: 4.2.1.51]
      Prephenate = phenylpyruvate + H(2)O + CO(2).
      • This enzyme in the enteric bacteria also possesses EC 5.4.99.5 activity and converts chorismate into prephenate.
      4 A0A0X8KIN5 A0A0X8KIN5 A0A1A0D2Y2 A0A1A0D2Y2
      Alpha-seco-amyrin synthase. [EC: 5.4.99.52]
      (3S)-2,3-epoxy-2,3-dihydrosqualene = alpha-seco-amyrin.
      • The enzyme from Arabidopsis thaliana is multifunctional and produces about equal amounts of alpha- and beta-seco-amyrin.
      • See EC 5.4.99.54.
      2 A0A0H4PJM5 A0A0H4PJM5
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