The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 6485: Rhea, isoform B

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
5 M9NDM3 (/ISS) M9PBW9 (/ISS) M9PEJ8 (/ISS) M9PF06 (/ISS) Q9VSL8 (/ISS)
Integrin binding GO:0005178
Interacting selectively and non-covalently with an integrin.
5 M9NDM3 (/IPI) M9PBW9 (/IPI) M9PEJ8 (/IPI) M9PF06 (/IPI) Q9VSL8 (/IPI)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
5 M9NDM3 (/IPI) M9PBW9 (/IPI) M9PEJ8 (/IPI) M9PF06 (/IPI) Q9VSL8 (/IPI)

There are 16 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Phagocytosis GO:0006909
An endocytosis process that results in the engulfment of external particulate material by phagocytes. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles.
5 M9NDM3 (/IMP) M9PBW9 (/IMP) M9PEJ8 (/IMP) M9PF06 (/IMP) Q9VSL8 (/IMP)
Cytoskeletal anchoring at plasma membrane GO:0007016
A cytoskeleton organization process that directly or indirectly links cytoskeletal filaments to the plasma membrane.
5 M9NDM3 (/ISS) M9PBW9 (/ISS) M9PEJ8 (/ISS) M9PF06 (/ISS) Q9VSL8 (/ISS)
Cell adhesion GO:0007155
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
5 M9NDM3 (/IMP) M9PBW9 (/IMP) M9PEJ8 (/IMP) M9PF06 (/IMP) Q9VSL8 (/IMP)
Cell adhesion GO:0007155
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
5 M9NDM3 (/TAS) M9PBW9 (/TAS) M9PEJ8 (/TAS) M9PF06 (/TAS) Q9VSL8 (/TAS)
Border follicle cell migration GO:0007298
The directed movement of a border cell through the nurse cells to reach the oocyte. An example of this is found in Drosophila melanogaster.
5 M9NDM3 (/IMP) M9PBW9 (/IMP) M9PEJ8 (/IMP) M9PF06 (/IMP) Q9VSL8 (/IMP)
Germ-band shortening GO:0007390
The spreading of the amnioserosa from its compressed state to cover the whole of the dorsal surface. Initiating in the thorax and spreading posteriorly, it is accompanied by the transition from a parasegmental to segmental division of the embryo.
5 M9NDM3 (/IMP) M9PBW9 (/IMP) M9PEJ8 (/IMP) M9PF06 (/IMP) Q9VSL8 (/IMP)
Terminal branching, open tracheal system GO:0007430
Formation of terminal branches in the open tracheal system. These are long cytoplasmic extensions that form fine tubules that transport oxygen directly to the tissues. An example of the process is found in Drosophila melanogaster.
5 M9NDM3 (/IMP) M9PBW9 (/IMP) M9PEJ8 (/IMP) M9PF06 (/IMP) Q9VSL8 (/IMP)
Apposition of dorsal and ventral imaginal disc-derived wing surfaces GO:0007475
The coming together of the dorsal and ventral surfaces of the imaginal disc-derived wing during the conversion of a folded single layered wing disc to a flat bilayered wing.
5 M9NDM3 (/IMP) M9PBW9 (/IMP) M9PEJ8 (/IMP) M9PF06 (/IMP) Q9VSL8 (/IMP)
Larval somatic muscle development GO:0007526
The process whose specific outcome is the progression of the larval somatic muscle over time, from its formation to the mature structure.
5 M9NDM3 (/IMP) M9PBW9 (/IMP) M9PEJ8 (/IMP) M9PF06 (/IMP) Q9VSL8 (/IMP)
Muscle attachment GO:0016203
The developmental process in which a skeletal muscle attaches to its target (such as bone or body wall).
5 M9NDM3 (/IMP) M9PBW9 (/IMP) M9PEJ8 (/IMP) M9PF06 (/IMP) Q9VSL8 (/IMP)
Cell adhesion mediated by integrin GO:0033627
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits.
5 M9NDM3 (/IMP) M9PBW9 (/IMP) M9PEJ8 (/IMP) M9PF06 (/IMP) Q9VSL8 (/IMP)
Maintenance of epithelial integrity, open tracheal system GO:0035160
Ensuring that tracheal tubes in an open tracheal system maintain their epithelial structure during the cell shape changes and movements that occur during the branching process.
5 M9NDM3 (/IMP) M9PBW9 (/IMP) M9PEJ8 (/IMP) M9PF06 (/IMP) Q9VSL8 (/IMP)
Sarcomere organization GO:0045214
The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
5 M9NDM3 (/IMP) M9PBW9 (/IMP) M9PEJ8 (/IMP) M9PF06 (/IMP) Q9VSL8 (/IMP)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
5 M9NDM3 (/IMP) M9PBW9 (/IMP) M9PEJ8 (/IMP) M9PF06 (/IMP) Q9VSL8 (/IMP)
Trachea morphogenesis GO:0060439
The process in which a trachea is generated and organized. The trachea is the portion of the airway that attaches to the bronchi as it branches.
5 M9NDM3 (/IMP) M9PBW9 (/IMP) M9PEJ8 (/IMP) M9PF06 (/IMP) Q9VSL8 (/IMP)
Cardiac muscle cell-cardiac muscle cell adhesion GO:0086042
The attachment of one cardiomyocyte to another cardiomyocyte via adhesion molecules.
5 M9NDM3 (/IMP) M9PBW9 (/IMP) M9PEJ8 (/IMP) M9PF06 (/IMP) Q9VSL8 (/IMP)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
5 M9NDM3 (/IDA) M9PBW9 (/IDA) M9PEJ8 (/IDA) M9PF06 (/IDA) Q9VSL8 (/IDA)
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
5 M9NDM3 (/ISS) M9PBW9 (/ISS) M9PEJ8 (/ISS) M9PF06 (/ISS) Q9VSL8 (/ISS)