The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5495: Serine/threonine-protein kinase WNK3

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 10 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
1 Q9BYP7 (/IDA)
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
1 Q80XP9 (/ISO)
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
1 Q80XP9 (/ISS)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
1 Q9BYP7 (/IDA)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
1 Q80XP9 (/ISO)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
1 Q9BYP7 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q9BYP7 (/IPI)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
1 Q9BYP7 (/ISS)
Chloride channel inhibitor activity GO:0019869
Stops, prevents, or reduces the activity of a chloride channel.
1 Q9BYP7 (/IDA)
Chloride channel inhibitor activity GO:0019869
Stops, prevents, or reduces the activity of a chloride channel.
1 Q80XP9 (/ISO)

There are 40 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
1 Q9BYP7 (/ISS)
Positive regulation of sodium ion transport GO:0010765
Any process that increases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q9BYP7 (/IDA)
Positive regulation of sodium ion transport GO:0010765
Any process that increases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q80XP9 (/ISO)
Positive regulation of sodium ion transport GO:0010765
Any process that increases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q80XP9 (/ISS)
Positive regulation of peptidyl-threonine phosphorylation GO:0010800
Any process that increases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.
1 Q9BYP7 (/IDA)
Positive regulation of peptidyl-threonine phosphorylation GO:0010800
Any process that increases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.
1 Q80XP9 (/ISO)
Positive regulation of peptidyl-threonine phosphorylation GO:0010800
Any process that increases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.
1 Q80XP9 (/ISS)
Positive regulation of ion transmembrane transporter activity GO:0032414
Any process that activates or increases the activity of an ion transporter.
1 Q9BYP7 (/IDA)
Positive regulation of ion transmembrane transporter activity GO:0032414
Any process that activates or increases the activity of an ion transporter.
1 Q80XP9 (/ISO)
Positive regulation of ion transmembrane transporter activity GO:0032414
Any process that activates or increases the activity of an ion transporter.
1 Q80XP9 (/ISS)
Intracellular signal transduction GO:0035556
The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
1 Q9BYP7 (/ISS)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
1 Q9BYP7 (/IMP)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
1 Q80XP9 (/ISO)
Protein autophosphorylation GO:0046777
The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation).
1 Q9BYP7 (/IDA)
Protein autophosphorylation GO:0046777
The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation).
1 Q80XP9 (/ISO)
Protein autophosphorylation GO:0046777
The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation).
1 Q80XP9 (/ISS)
Positive regulation of calcium ion transport GO:0051928
Any process that activates or increases the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q9BYP7 (/IMP)
Positive regulation of calcium ion transport GO:0051928
Any process that activates or increases the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q80XP9 (/ISO)
Protein targeting to plasma membrane GO:0072661
The process of directing proteins towards the plasma membrane; usually uses signals contained within the protein.
1 Q9BYP7 (/IMP)
Protein targeting to plasma membrane GO:0072661
The process of directing proteins towards the plasma membrane; usually uses signals contained within the protein.
1 Q80XP9 (/ISO)
Protein targeting to plasma membrane GO:0072661
The process of directing proteins towards the plasma membrane; usually uses signals contained within the protein.
1 Q80XP9 (/ISS)
Positive regulation of establishment of protein localization to plasma membrane GO:0090004
Any process that increases the frequency, rate or extent of the directed movement of a protein to a specific location in the plasma membrane.
1 Q9BYP7 (/IDA)
Positive regulation of establishment of protein localization to plasma membrane GO:0090004
Any process that increases the frequency, rate or extent of the directed movement of a protein to a specific location in the plasma membrane.
1 Q80XP9 (/ISO)
Positive regulation of establishment of protein localization to plasma membrane GO:0090004
Any process that increases the frequency, rate or extent of the directed movement of a protein to a specific location in the plasma membrane.
1 Q80XP9 (/ISS)
Negative regulation of pancreatic juice secretion GO:0090188
Any process that decreases the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine.
1 Q80XP9 (/IMP)
Regulation of calcium ion import GO:0090279
Any process that modulates the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle.
1 Q9BYP7 (/IMP)
Regulation of calcium ion import GO:0090279
Any process that modulates the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle.
1 Q80XP9 (/ISO)
Regulation of calcium ion import GO:0090279
Any process that modulates the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle.
1 Q80XP9 (/ISS)
Regulation of ion homeostasis GO:2000021
Any process that modulates the frequency, rate or extent of ion homeostasis.
1 Q9BYP7 (/IMP)
Regulation of ion homeostasis GO:2000021
Any process that modulates the frequency, rate or extent of ion homeostasis.
1 Q80XP9 (/ISO)
Positive regulation of sodium ion transmembrane transporter activity GO:2000651
Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transporter activity.
1 Q9BYP7 (/IDA)
Positive regulation of sodium ion transmembrane transporter activity GO:2000651
Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transporter activity.
1 Q9BYP7 (/IMP)
Positive regulation of sodium ion transmembrane transporter activity GO:2000651
Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transporter activity.
1 Q80XP9 (/ISO)
Positive regulation of sodium ion transmembrane transporter activity GO:2000651
Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transporter activity.
1 Q80XP9 (/ISS)
Positive regulation of rubidium ion transport GO:2000682
Any process that activates or increases the frequency, rate or extent of rubidium ion transport.
1 Q9BYP7 (/IDA)
Positive regulation of rubidium ion transport GO:2000682
Any process that activates or increases the frequency, rate or extent of rubidium ion transport.
1 Q80XP9 (/ISO)
Positive regulation of rubidium ion transport GO:2000682
Any process that activates or increases the frequency, rate or extent of rubidium ion transport.
1 Q80XP9 (/ISS)
Positive regulation of rubidium ion transmembrane transporter activity GO:2000688
Any process that activates or increases the frequency, rate or extent of rubidium ion transmembrane transporter activity.
1 Q9BYP7 (/IDA)
Positive regulation of rubidium ion transmembrane transporter activity GO:2000688
Any process that activates or increases the frequency, rate or extent of rubidium ion transmembrane transporter activity.
1 Q80XP9 (/ISO)
Positive regulation of rubidium ion transmembrane transporter activity GO:2000688
Any process that activates or increases the frequency, rate or extent of rubidium ion transmembrane transporter activity.
1 Q80XP9 (/ISS)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q9BYP7 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q80XP9 (/ISO)
Adherens junction GO:0005912
A cell junction at which anchoring proteins (cadherins or integrins) extend through the plasma membrane and are attached to actin filaments.
1 Q80XP9 (/IDA)
Adherens junction GO:0005912
A cell junction at which anchoring proteins (cadherins or integrins) extend through the plasma membrane and are attached to actin filaments.
1 Q9BYP7 (/ISS)
Bicellular tight junction GO:0005923
An occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet; the outer leaflets of the two interacting plasma membranes are seen to be tightly apposed where sealing strands are present. Each sealing strand is composed of a long row of transmembrane adhesion proteins embedded in each of the two interacting plasma membranes.
1 Q80XP9 (/IDA)
Bicellular tight junction GO:0005923
An occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet; the outer leaflets of the two interacting plasma membranes are seen to be tightly apposed where sealing strands are present. Each sealing strand is composed of a long row of transmembrane adhesion proteins embedded in each of the two interacting plasma membranes.
1 Q9BYP7 (/ISS)