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CATH Superfamily 3.10.20.90

Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2523: Diacylglycerol kinase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Diacylglycerol kinase (ATP). [EC: 2.7.1.107]
ATP + 1,2-diacyl-sn-glycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate.
  • Involved in synthesis of membrane phospholipids and the neutral lipid triacylglycerol.
  • Activity is stimulated by certain phospholipids.
  • In plants and animals the product 1,2-diacyl-sn-glycerol 3-phosphate is an important second messenger.
  • cf. EC 2.7.1.174.
 22 A0A0B4K716 A0A0B4KHZ4 A0A0M5J2H7 A0A0R1E5Y9 A0A0R1E610 A0A0R1E6H9 A0A0R1E782 A0A0R1EBE8 A8JR94 B3P8B2
(12 more...)