The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"C2 domain
".
FunFam 7998: Serine/threonine-protein kinase N1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 15 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
|
1 | Q16512 (/IDA) |
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
|
1 | Q16512 (/TAS) |
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
|
1 | Q16512 (/EXP) |
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
|
1 | Q16512 (/IDA) |
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
|
1 | Q16512 (/TAS) |
Protein kinase C binding GO:0005080
Interacting selectively and non-covalently with protein kinase C.
|
1 | Q16512 (/IPI) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q16512 (/IPI) |
GTP-Rho binding GO:0017049
Interacting selectively and non-covalently with the GTP-bound form of the Rho protein.
|
1 | Q16512 (/IDA) |
Ligand-dependent nuclear receptor transcription coactivator activity GO:0030374
The function of a transcription cofactor that activates transcription in conjuction with a ligand-dependent nuclear receptor from a RNA polymerase II promoter; does not bind DNA itself.
|
1 | Q16512 (/IDA) |
Ligand-dependent nuclear receptor transcription coactivator activity GO:0030374
The function of a transcription cofactor that activates transcription in conjuction with a ligand-dependent nuclear receptor from a RNA polymerase II promoter; does not bind DNA itself.
|
1 | Q16512 (/IMP) |
Histone kinase activity (H3-T11 specific) GO:0035402
Catalysis of the transfer of a phosphate group to the threonine-11 residue of the N-terminal tail of histone H3.
|
1 | Q16512 (/IDA) |
Histone binding GO:0042393
Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
|
1 | Q16512 (/IDA) |
Histone deacetylase binding GO:0042826
Interacting selectively and non-covalently with the enzyme histone deacetylase.
|
1 | Q16512 (/IDA) |
Rac GTPase binding GO:0048365
Interacting selectively and non-covalently with Rac protein, any member of the Rac subfamily of the Ras superfamily of monomeric GTPases.
|
1 | Q16512 (/IDA) |
Androgen receptor binding GO:0050681
Interacting selectively and non-covalently with an androgen receptor.
|
1 | Q16512 (/IDA) |
There are 9 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Regulation of transcription from RNA polymerase II promoter GO:0006357
Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | Q16512 (/IDA) |
Regulation of transcription from RNA polymerase II promoter GO:0006357
Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | Q16512 (/IMP) |
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
|
1 | Q16512 (/IDA) |
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
|
1 | Q16512 (/TAS) |
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
|
1 | Q16512 (/TAS) |
Activation of JUN kinase activity GO:0007257
The initiation of the activity of the inactive enzyme JUN kinase (JNK).
|
1 | Q16512 (/TAS) |
Epithelial cell migration GO:0010631
The orderly movement of an epithelial cell from one site to another, often during the development of a multicellular organism.
|
1 | Q16512 (/IMP) |
Histone H3-T11 phosphorylation GO:0035407
The modification of histone H3 by the addition of an phosphate group to a threonine residue at position 11 of the histone.
|
1 | Q16512 (/IDA) |
Regulation of cell motility GO:2000145
Any process that modulates the frequency, rate or extent of cell motility.
|
1 | Q16512 (/IMP) |
There are 7 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q16512 (/IDA) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q16512 (/TAS) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q16512 (/IDA) |
Endosome GO:0005768
A vacuole to which materials ingested by endocytosis are delivered.
|
1 | Q16512 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q16512 (/TAS) |
Midbody GO:0030496
A thin cytoplasmic bridge formed between daughter cells at the end of cytokinesis. The midbody forms where the contractile ring constricts, and may persist for some time before finally breaking to complete cytokinesis.
|
1 | Q16512 (/IDA) |
Cleavage furrow GO:0032154
The cleavage furrow is a plasma membrane invagination at the cell division site. The cleavage furrow begins as a shallow groove and eventually deepens to divide the cytoplasm.
|
1 | Q16512 (/IDA) |