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CATH Superfamily 2.60.40.150

C2 domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
C2 domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 15265: C2 calcium/lipid-binding plant phosphoribosyltrans...

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Phosphatidylserine decarboxylase. [EC: 4.1.1.65]
Phosphatidyl-L-serine = phosphatidylethanolamine + CO(2).
    		 21 A0A0B2NU90 A0A0B2NUM6 A0A0B2NVU4 A0A0B2PI55 A0A0B2Q631 A0A0B2QQA9 A0A0B2R2W9 A0A0B2R3P5 A0A0B2R708 A0A0B2RDG0
    (11 more...)
    Transferred entry: 2.3.2.23, 2.3.2.27 and 6.2.1.45. [EC: 6.3.2.19]
      		4 A0A0B2NZQ3 A0A0B2R064 A0A0B2R438 I1JKA3
      Lysophospholipase. [EC: 3.1.1.5]
      2-lysophosphatidylcholine + H(2)O = glycerophosphocholine + a carboxylate.
        		 1 A0A151S3V8
        Protein kinase C. [EC: 2.7.11.13]
        ATP + a protein = ADP + a phosphoprotein.
        • A family of serine- and threonine-specific protein kinases that depend on lipids for activity.
        • They can be activated by calcium but have a requirement for the second messenger diacylglycerol.
        • Members of this group of enzymes phosphorylate a wide variety of protein targets and are known to be involved in diverse cell- signaling pathways.
        • Members of the protein kinase C family also serve as major receptors for phorbol esters, a class of tumor promoters.
        • Formerly EC 2.7.1.37.
        		 1 A0A151SL79
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