The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"C2 domain
".
FunFam 15084: Dysferlin (Predicted), isoform CRA_a
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 9 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
|
2 | A6QQP7 (/ISS) Q9ESD7 (/ISS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | O75923 (/IPI) Q9ESD7 (/IPI) |
|
Phospholipid binding GO:0005543
Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester.
|
2 | A6QQP7 (/ISS) Q9ESD7 (/ISS) |
|
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
|
1 | O75923 (/IDA) |
|
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
|
1 | Q9ESD7 (/ISO) |
|
Phospholipid binding GO:0005543
Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester.
|
1 | O75923 (/IDA) |
|
Phospholipid binding GO:0005543
Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester.
|
1 | Q9ESD7 (/ISO) |
|
Calcium-dependent phospholipid binding GO:0005544
Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester, in the presence of calcium.
|
1 | O75923 (/IMP) |
|
Calcium-dependent phospholipid binding GO:0005544
Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester, in the presence of calcium.
|
1 | Q9ESD7 (/ISO) |
There are 8 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Plasma membrane repair GO:0001778
The resealing of a cell plasma membrane after cellular wounding due to, for instance, mechanical stress.
|
4 | A0A0R4IAA9 (/IMP) E7F4H1 (/IMP) F1QIS3 (/IMP) Q9ESD7 (/IMP) |
|
T-tubule organization GO:0033292
A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of the T-tubule. A T-tubule is an invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril.
|
3 | A0A0R4IAA9 (/IMP) E7F4H1 (/IMP) F1QIS3 (/IMP) |
|
Muscle organ morphogenesis GO:0048644
The process in which the anatomical structures of muscle are generated and organized.
|
3 | A0A0R4IAA9 (/IMP) E7F4H1 (/IMP) F1QIS3 (/IMP) |
|
Cell wall repair GO:0071433
A process of cell wall organization that results in the restoration of the cell wall following damage.
|
3 | A0A0R4IAA9 (/IMP) E7F4H1 (/IMP) F1QIS3 (/IMP) |
|
Muscle contraction GO:0006936
A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis.
|
2 | O75923 (/TAS) Q9ESD7 (/TAS) |
|
Plasma membrane repair GO:0001778
The resealing of a cell plasma membrane after cellular wounding due to, for instance, mechanical stress.
|
1 | Q9ESD7 (/IDA) |
|
Vesicle fusion GO:0006906
Fusion of the membrane of a transport vesicle with its target membrane.
|
1 | Q9ESD7 (/IMP) |
|
Vesicle fusion GO:0006906
Fusion of the membrane of a transport vesicle with its target membrane.
|
1 | A6QQP7 (/ISS) |
There are 25 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
T-tubule GO:0030315
Invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril. The ends of T-tubules make contact with the sarcoplasmic reticulum membrane.
|
5 | A0A0R4IAA9 (/IDA) E7F4H1 (/IDA) F1QIS3 (/IDA) O75923 (/IDA) Q9ESD7 (/IDA) |
|
Sarcolemma GO:0042383
The outer membrane of a muscle cell, consisting of the plasma membrane, a covering basement membrane (about 100 nm thick and sometimes common to more than one fiber), and the associated loose network of collagen fibers.
|
5 | A0A0R4IAA9 (/IDA) E7F4H1 (/IDA) F1QIS3 (/IDA) O75923 (/IDA) Q9ESD7 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | A6QQP7 (/ISS) Q9ESD7 (/ISS) |
|
Cytoplasmic vesicle membrane GO:0030659
The lipid bilayer surrounding a cytoplasmic vesicle.
|
2 | O75923 (/TAS) Q9ESD7 (/TAS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | D4A6X1 (/IDA) |
|
Endosome GO:0005768
A vacuole to which materials ingested by endocytosis are delivered.
|
1 | O75923 (/IDA) |
|
Endosome GO:0005768
A vacuole to which materials ingested by endocytosis are delivered.
|
1 | Q9ESD7 (/ISO) |
|
Early endosome GO:0005769
A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways.
|
1 | O75923 (/IDA) |
|
Early endosome GO:0005769
A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways.
|
1 | Q9ESD7 (/ISO) |
|
Late endosome GO:0005770
A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
|
1 | O75923 (/IDA) |
|
Late endosome GO:0005770
A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
|
1 | Q9ESD7 (/ISO) |
|
Microtubule organizing center GO:0005815
An intracellular structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with their minus ends, plus ends or sides.
|
1 | O75923 (/IDA) |
|
Microtubule organizing center GO:0005815
An intracellular structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with their minus ends, plus ends or sides.
|
1 | Q9ESD7 (/ISO) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | O75923 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q9ESD7 (/ISO) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | O75923 (/TAS) |
|
Lamellipodium GO:0030027
A thin sheetlike process extended by the leading edge of a migrating cell or extending cell process; contains a dense meshwork of actin filaments.
|
1 | Q9ESD7 (/IDA) |
|
Endocytic vesicle GO:0030139
A membrane-bounded intracellular vesicle formed by invagination of the plasma membrane around an extracellular substance. Endocytic vesicles fuse with early endosomes to deliver the cargo for further sorting.
|
1 | O75923 (/IDA) |
|
Endocytic vesicle GO:0030139
A membrane-bounded intracellular vesicle formed by invagination of the plasma membrane around an extracellular substance. Endocytic vesicles fuse with early endosomes to deliver the cargo for further sorting.
|
1 | Q9ESD7 (/ISO) |
|
T-tubule GO:0030315
Invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril. The ends of T-tubules make contact with the sarcoplasmic reticulum membrane.
|
1 | Q9ESD7 (/ISO) |
|
Cytoplasmic vesicle GO:0031410
A vesicle found in the cytoplasm of a cell.
|
1 | Q9ESD7 (/IDA) |
|
Sarcolemma GO:0042383
The outer membrane of a muscle cell, consisting of the plasma membrane, a covering basement membrane (about 100 nm thick and sometimes common to more than one fiber), and the associated loose network of collagen fibers.
|
1 | Q9ESD7 (/ISO) |
|
Sarcolemma GO:0042383
The outer membrane of a muscle cell, consisting of the plasma membrane, a covering basement membrane (about 100 nm thick and sometimes common to more than one fiber), and the associated loose network of collagen fibers.
|
1 | A6QQP7 (/ISS) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
1 | O75923 (/IDA) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
1 | Q9ESD7 (/ISO) |