The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"C2 domain
".
FunFam 118: Phosphatidylinositol 3-kinase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
|
1 | P22543 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | P22543 (/IPI) |
|
1-phosphatidylinositol-3-kinase activity GO:0016303
Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ADP + 2 H(+).
|
1 | P22543 (/IDA) |
|
1-phosphatidylinositol-3-kinase activity GO:0016303
Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ADP + 2 H(+).
|
1 | P22543 (/IMP) |
There are 5 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
|
1 | P22543 (/IDA) |
|
Pexophagy GO:0030242
The process in which peroxisomes are delivered to the vacuole and degraded in response to changing nutrient conditions.
|
1 | P22543 (/IMP) |
|
Positive regulation of transcription elongation from RNA polymerase II promoter GO:0032968
Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.
|
1 | P22543 (/IMP) |
|
Phosphatidylinositol phosphorylation GO:0046854
The process of introducing one or more phosphate groups into a phosphatidylinositol, any glycerophosphoinositol having one phosphatidyl group esterified to one of the hydroxy groups of inositol.
|
1 | P22543 (/IDA) |
|
Phosphatidylinositol phosphorylation GO:0046854
The process of introducing one or more phosphate groups into a phosphatidylinositol, any glycerophosphoinositol having one phosphatidyl group esterified to one of the hydroxy groups of inositol.
|
1 | P22543 (/IMP) |
There are 7 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Fungal-type vacuole membrane GO:0000329
The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae.
|
1 | P22543 (/IDA) |
|
Pre-autophagosomal structure GO:0000407
A punctate structure localized in the vicinity of the vacuole that is required for the formation of autophagosomes.
|
1 | P22543 (/IDA) |
|
Endosome GO:0005768
A vacuole to which materials ingested by endocytosis are delivered.
|
1 | P22543 (/IDA) |
|
Peroxisome GO:0005777
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
|
1 | P22543 (/IDA) |
|
Phosphatidylinositol 3-kinase complex, class III, type I GO:0034271
A class III phosphatidylinositol 3-kinase complex that is involved in autophagy. In budding yeast, this complex consists of Vps30p, Vps34p, Apg14p and Vps15p.
|
1 | P22543 (/IDA) |
|
Phosphatidylinositol 3-kinase complex, class III, type II GO:0034272
A class III phosphatidylinositol 3-kinase complex that is involved in vacuolar protein sorting (VPS) via endosomes. In budding yeast, this complex consists of Vps30p, Vps34p, Vps38 and Vps15p.
|
1 | P22543 (/IDA) |
|
Nucleus-vacuole junction GO:0071561
An organelle membrane contact site formed between the vacuole membrane and the outer nuclear membrane. In S. cerevisiae these contacts are mediated through direct physical interaction between Vac8p and Nvj1p.
|
1 | P22543 (/IDA) |
