The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Jelly Rolls
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 54745: CAMP-dependent kinase, regulatory protein

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 41 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
18 A9C3T0 (/IPI) C1PIG4 (/IPI) P00515 (/IPI) P05207 (/IPI) P05987 (/IPI) P07278 (/IPI) P0C605 (/IPI) P12367 (/IPI) P12368 (/IPI) P12369 (/IPI)
(8 more)
CGMP-dependent protein kinase activity GO:0004692
Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of cGMP.
8 O76360 (/IDA) P0C605 (/IDA) P32023 (/IDA) Q03042 (/IDA) Q03043 (/IDA) Q13976 (/IDA) Q64595 (/IDA) Q8I719 (/IDA)
CAMP-dependent protein kinase regulator activity GO:0008603
Modulation of the activity of the enzyme cAMP-dependent protein kinase.
6 P12368 (/IDA) P12369 (/IDA) P13861 (/IDA) P31323 (/IDA) P31324 (/IDA) Q9HEW1 (/IDA)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
4 P32023 (/NAS) Q03042 (/NAS) Q03043 (/NAS) Q9VL34 (/NAS)
CGMP-dependent protein kinase activity GO:0004692
Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of cGMP.
4 O77676 (/ISS) P00516 (/ISS) Q03042 (/ISS) Q9VL34 (/ISS)
CAMP-dependent protein kinase inhibitor activity GO:0004862
Stops, prevents or reduces the activity of a cAMP-dependent protein kinase.
4 P05987 (/IDA) P07278 (/IDA) P13861 (/IDA) P31323 (/IDA)
CGMP-dependent protein kinase activity GO:0004692
Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of cGMP.
3 P00516 (/TAS) Q13237 (/TAS) Q13976 (/TAS)
Calcium channel regulator activity GO:0005246
Modulates the activity of a calcium channel.
3 O77676 (/ISS) P00516 (/ISS) P0C605 (/ISS)
CAMP-dependent protein kinase regulator activity GO:0008603
Modulation of the activity of the enzyme cAMP-dependent protein kinase.
3 A2R7J4 (/IMP) P05987 (/IMP) P36600 (/IMP)
CAMP binding GO:0030552
Interacting selectively and non-covalently with cAMP, the nucleotide cyclic AMP (adenosine 3',5'-cyclophosphate).
3 P05987 (/IDA) P12368 (/IDA) P12369 (/IDA)
Protein kinase A catalytic subunit binding GO:0034236
Interacting selectively and non-covalently with one or both of the catalytic subunits of protein kinase A.
3 P05987 (/IPI) P13861 (/IPI) P31323 (/IPI)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
3 A9LNM8 (/IDA) P12368 (/IDA) Q64595 (/IDA)
Cyclic nucleotide-dependent protein kinase activity GO:0004690
Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of a cyclic nucleotide.
2 P32023 (/ISS) Q03043 (/ISS)
CAMP-dependent protein kinase inhibitor activity GO:0004862
Stops, prevents or reduces the activity of a cAMP-dependent protein kinase.
2 P12367 (/ISO) P31324 (/ISO)
CAMP-dependent protein kinase regulator activity GO:0008603
Modulation of the activity of the enzyme cAMP-dependent protein kinase.
2 A2R7J4 (/IGI) Q9HEW1 (/IGI)
CAMP-dependent protein kinase regulator activity GO:0008603
Modulation of the activity of the enzyme cAMP-dependent protein kinase.
2 P12367 (/ISO) P31324 (/ISO)
CAMP-dependent protein kinase regulator activity GO:0008603
Modulation of the activity of the enzyme cAMP-dependent protein kinase.
2 P30625 (/ISS) Q7KQK0 (/ISS)
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
2 P12368 (/IMP) P12369 (/IMP)
Ubiquitin protein ligase binding GO:0031625
Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.
2 P13861 (/IDA) P31323 (/IDA)
Ubiquitin protein ligase binding GO:0031625
Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.
2 P12367 (/ISO) P31324 (/ISO)
Protein kinase A catalytic subunit binding GO:0034236
Interacting selectively and non-covalently with one or both of the catalytic subunits of protein kinase A.
2 P12368 (/IC) P12369 (/IC)
Protein kinase A catalytic subunit binding GO:0034236
Interacting selectively and non-covalently with one or both of the catalytic subunits of protein kinase A.
2 P12367 (/ISO) P31324 (/ISO)
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
1 P0C605 (/IDA)
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
1 Q13237 (/TAS)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
1 P0C605 (/IDA)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
1 Q13976 (/TAS)
CGMP-dependent protein kinase activity GO:0004692
Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of cGMP.
1 P0C605 (/ISO)
CAMP-dependent protein kinase inhibitor activity GO:0004862
Stops, prevents or reduces the activity of a cAMP-dependent protein kinase.
1 P07278 (/IMP)
Calcium channel regulator activity GO:0005246
Modulates the activity of a calcium channel.
1 Q13976 (/IDA)
Calcium channel regulator activity GO:0005246
Modulates the activity of a calcium channel.
1 P0C605 (/ISO)
CAMP-dependent protein kinase regulator activity GO:0008603
Modulation of the activity of the enzyme cAMP-dependent protein kinase.
1 P13861 (/NAS)
CAMP-dependent protein kinase regulator activity GO:0008603
Modulation of the activity of the enzyme cAMP-dependent protein kinase.
1 P31323 (/TAS)
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
1 P31324 (/IPI)
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
1 P12368 (/IPI)
CAMP binding GO:0030552
Interacting selectively and non-covalently with cAMP, the nucleotide cyclic AMP (adenosine 3',5'-cyclophosphate).
1 P05987 (/IMP)
CGMP binding GO:0030553
Interacting selectively and non-covalently with cGMP, the nucleotide cyclic GMP (guanosine 3',5'-cyclophosphate).
1 P0C605 (/IDA)
Small molecule binding GO:0036094
Interacting selectively and non-covalently with a small molecule, any low molecular weight, monomeric, non-encoded molecule.
1 P12368 (/IDA)
Chemoattractant activity GO:0042056
Providing the environmental signal that initiates the directed movement of a motile cell or organism towards a higher concentration of that signal.
1 O76360 (/IGI)
Chemoattractant activity GO:0042056
Providing the environmental signal that initiates the directed movement of a motile cell or organism towards a higher concentration of that signal.
1 O76360 (/IMP)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 P07278 (/IPI)
Mitogen-activated protein kinase p38 binding GO:0048273
Interacting selectively and non-covalently with mitogen-activated protein kinase p38, an enzyme that catalyzes the transfer of phosphate from ATP to hydroxyl side chains on proteins in response to mitogen activation.
1 A9LNM8 (/IDA)

There are 164 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
6 O76360 (/IDA) P0C605 (/IDA) P32023 (/IDA) Q03042 (/IDA) Q03043 (/IDA) Q8I719 (/IDA)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
4 P32023 (/NAS) Q03042 (/NAS) Q03043 (/NAS) Q9VL34 (/NAS)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
3 Q13237 (/TAS) Q13976 (/TAS) Q64595 (/TAS)
Regulation of GTPase activity GO:0043087
Any process that modulates the rate of GTP hydrolysis by a GTPase.
3 O77676 (/ISS) P00516 (/ISS) P0C605 (/ISS)
Modulation of development of symbiont involved in interaction with host GO:0044145
Any process that modulates the frequency, rate or extent of the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism.
3 Q385V6 (/IMP) Q9GPG5 (/IMP) Q9GU80 (/IMP)
Quorum sensing involved in interaction with host GO:0052106
The process in which a community of single-celled organisms living in intimate contact with a host organism monitors population density by detecting the concentration of small diffusible signal molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction.
3 Q385V6 (/IMP) Q9GPG5 (/IMP) Q9GU80 (/IMP)
Negative regulation of platelet aggregation GO:0090331
Any process that decreases the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.
3 O77676 (/ISS) P00516 (/ISS) P0C605 (/ISS)
Renal water homeostasis GO:0003091
Renal process involved in the maintenance of an internal steady state of water in the body.
2 P13861 (/TAS) P31323 (/TAS)
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
2 Q13237 (/TAS) Q13976 (/TAS)
Blood coagulation GO:0007596
The sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.
2 P13861 (/TAS) P31323 (/TAS)
Short-term memory GO:0007614
The memory process that deals with the storage, retrieval and modification of information received a short time (up to about 30 minutes) ago. This type of memory is typically dependent on direct, transient effects of second messenger activation.
2 P32023 (/IMP) Q03043 (/IMP)
Long-term memory GO:0007616
The memory process that deals with the storage, retrieval and modification of information a long time (typically weeks, months or years) after receiving that information. This type of memory is typically dependent on gene transcription regulated by second messenger activation.
2 P32023 (/IMP) Q03043 (/IMP)
Feeding behavior GO:0007631
Behavior associated with the intake of food.
2 P32023 (/TAS) Q03043 (/TAS)
Regulation of heart contraction GO:0008016
Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process in which the heart decreases in volume in a characteristic way to propel blood through the body.
2 P32023 (/IMP) Q03043 (/IMP)
Motor neuron axon guidance GO:0008045
The process in which the migration of an axon growth cone of a motor neuron is directed to a specific target site in response to a combination of attractive and repulsive cues.
2 P32023 (/IMP) Q03043 (/IMP)
Larval locomotory behavior GO:0008345
Locomotory behavior in a larval (immature) organism.
2 P32023 (/IMP) Q03043 (/IMP)
Response to sucrose GO:0009744
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sucrose stimulus.
2 P32023 (/IDA) Q03043 (/IDA)
Regulation of gene expression GO:0010468
Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
2 O76360 (/IMP) P05987 (/IMP)
Regulation of BMP signaling pathway GO:0030510
Any process that modulates the frequency, rate or extent of the activity of any BMP receptor signaling pathway.
2 P32023 (/IMP) Q03043 (/IMP)
Larval feeding behavior GO:0030536
Feeding behavior in a larval (immature) organism.
2 P32023 (/IMP) Q03043 (/IMP)
Larval feeding behavior GO:0030536
Feeding behavior in a larval (immature) organism.
2 P32023 (/TAS) Q03043 (/TAS)
Regulation of response to food GO:0032095
Any process that modulates the frequency, rate or extent of a response to a food stimulus.
2 P32023 (/IMP) Q03043 (/IMP)
Activation of protein kinase A activity GO:0034199
Any process that initiates the activity of the inactive enzyme protein kinase A.
2 P13861 (/TAS) P31323 (/TAS)
Intracellular signal transduction GO:0035556
The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
2 P13861 (/TAS) P31323 (/TAS)
Asexual sporulation resulting in formation of a cellular spore GO:0043936
The formation of a cellular spore derived from the products of mitosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction.
2 A2R7J4 (/IMP) Q96UX3 (/IMP)
Positive regulation of asexual sporulation resulting in formation of a cellular spore GO:0043945
Any process that activates, maintains or increases the frequency, rate or extent of the formation of a cellular spore derived from the products of mitosis.
2 A2R7J4 (/IMP) Q96UX3 (/IMP)
Regulation of protein kinase activity GO:0045859
Any process that modulates the frequency, rate or extent of protein kinase activity.
2 P12368 (/IDA) P12369 (/IDA)
Habituation GO:0046959
A decrease in a behavioral response to a repeated stimulus. This is exemplified by the failure of a person to show a startle response to a loud noise that has been repeatedly presented.
2 P32023 (/IMP) Q03043 (/IMP)
Cellular response to glucagon stimulus GO:0071377
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus.
2 P13861 (/TAS) P31323 (/TAS)
Response to clozapine GO:0097338
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a clozapine stimulus.
2 P12368 (/IEP) P12369 (/IEP)
Regulation of meiotic cell cycle process involved in oocyte maturation GO:1903538
Any process that modulates the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation.
2 C1PIG4 (/IMP) P05207 (/IMP)
Positive regulation of meiotic cell cycle process involved in oocyte maturation GO:1904146
Any process that activates or increases the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation.
2 C1PIG4 (/IMP) P05207 (/IMP)
Negative regulation of cAMP-dependent protein kinase activity GO:2000480
Any process that stops, prevents or reduces the frequency, rate or extent of cAMP-dependent protein kinase activity.
2 P13861 (/IDA) P31323 (/IDA)
Negative regulation of cAMP-dependent protein kinase activity GO:2000480
Any process that stops, prevents or reduces the frequency, rate or extent of cAMP-dependent protein kinase activity.
2 C1PIG4 (/IMP) P05207 (/IMP)
Negative regulation of cAMP-dependent protein kinase activity GO:2000480
Any process that stops, prevents or reduces the frequency, rate or extent of cAMP-dependent protein kinase activity.
2 P12367 (/ISO) P31324 (/ISO)
G2/M transition of mitotic cell cycle GO:0000086
The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex.
1 P31323 (/TAS)
Activation of MAPK activity GO:0000187
The initiation of the activity of the inactive enzyme MAP kinase (MAPK).
1 P05987 (/IMP)
Neuron migration GO:0001764
The characteristic movement of an immature neuron from germinal zones to specific positions where they will reside as they mature.
1 P0C605 (/IMP)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
1 Q13237 (/IMP)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
1 Q61410 (/ISO)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
1 Q9VL34 (/ISS)
Fatty acid metabolic process GO:0006631
The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
1 P31324 (/IMP)
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
1 P0C605 (/IDA)
Positive regulation of cytosolic calcium ion concentration GO:0007204
Any process that increases the concentration of calcium ions in the cytosol.
1 A9LNM8 (/IMP)
Spermatid development GO:0007286
The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure.
1 A9LNM8 (/IEP)
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
1 P81900 (/IMP)
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
1 A9LNM8 (/IEP)
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
1 A9LNM8 (/IEP)
Larval somatic muscle development GO:0007526
The process whose specific outcome is the progression of the larval somatic muscle over time, from its formation to the mature structure.
1 Q03042 (/IMP)
Learning GO:0007612
Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience.
1 P31324 (/IMP)
Rhythmic behavior GO:0007622
The specific behavior of an organism that recur with measured regularity.
1 P81900 (/TAS)
Circadian rhythm GO:0007623
Any biological process in an organism that recurs with a regularity of approximately 24 hours.
1 Q61410 (/IMP)
Circadian rhythm GO:0007623
Any biological process in an organism that recurs with a regularity of approximately 24 hours.
1 P81900 (/NAS)
Chemosensory behavior GO:0007635
Behavior that is dependent upon the sensation of chemicals.
1 O76360 (/IGI)
Chemosensory behavior GO:0007635
Behavior that is dependent upon the sensation of chemicals.
1 O76360 (/IMP)
Protein localization GO:0008104
Any process in which a protein is transported to, or maintained in, a specific location.
1 Q9HEW1 (/IGI)
Insulin receptor signaling pathway GO:0008286
The series of molecular signals generated as a consequence of the insulin receptor binding to insulin.
1 O76360 (/IGI)
Determination of adult lifespan GO:0008340
The control of viability and duration in the adult phase of the life-cycle.
1 O76360 (/IMP)
Olfactory learning GO:0008355
Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue.
1 O76360 (/IMP)
Cellular response to starvation GO:0009267
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.
1 Q9HEW1 (/IMP)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
1 Q96UX3 (/IMP)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 P05987 (/IDA)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 P05987 (/IMP)
Protein kinase A signaling GO:0010737
A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase A, which occurs as a result of a single trigger reaction or compound.
1 P05987 (/IMP)
Positive regulation of cGMP-mediated signaling GO:0010753
Any process that increases the rate, frequency or extent of cGMP-mediated signaling. cGMP-mediated signaling is a series of molecular signals in which a cell uses cyclic GMP to convert an extracellular signal into a response.
1 O76360 (/IGI)
Positive regulation of cGMP-mediated signaling GO:0010753
Any process that increases the rate, frequency or extent of cGMP-mediated signaling. cGMP-mediated signaling is a series of molecular signals in which a cell uses cyclic GMP to convert an extracellular signal into a response.
1 O76360 (/IMP)
Regulation of glucose metabolic process GO:0010906
Any process that modulates the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose.
1 Q03042 (/IMP)
Negative regulation of inositol phosphate biosynthetic process GO:0010920
Any process that decreases the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.
1 A9LNM8 (/IMP)
Negative regulation of glutamate secretion GO:0014050
Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of glutamate.
1 A9LNM8 (/IMP)
Negative regulation of smooth muscle cell migration GO:0014912
Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell migration.
1 A9LNM8 (/IMP)
Dendrite development GO:0016358
The process whose specific outcome is the progression of the dendrite over time, from its formation to the mature structure. A dendrite is a freely branching protoplasmic process of a nerve cell.
1 P0C605 (/IMP)
Peptidyl-serine phosphorylation GO:0018105
The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine.
1 O76360 (/IDA)
CGMP-mediated signaling GO:0019934
Any intracellular signal transduction in which the signal is passed on within the cell via cyclic GMP (cGMP). Includes production of cGMP, and downstream effectors that further transmit the signal within the cell.
1 P0C605 (/IMP)
Cerebellum development GO:0021549
The process whose specific outcome is the progression of the cerebellum over time, from its formation to the mature structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. In mice, the cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.
1 A9LNM8 (/IEP)
Actin cytoskeleton organization GO:0030036
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
1 Q13976 (/TAS)
Negative regulation of cell growth GO:0030308
Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.
1 O76360 (/IMP)
Sleep GO:0030431
Any process in which an organism enters and maintains a periodic, readily reversible state of reduced awareness and metabolic activity. Usually accompanied by physical relaxation, the onset of sleep in humans and other mammals is marked by a change in the electrical activity of the brain.
1 O76360 (/IMP)
Sporulation resulting in formation of a cellular spore GO:0030435
The process in which a relatively unspecialized cell acquires the specialized features of a cellular spore, a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction.
1 P05987 (/IMP)
Filamentous growth GO:0030447
The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
1 Q9HEW1 (/IGI)
Filamentous growth GO:0030447
The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
1 Q9HEW1 (/IMP)
Hyphal growth GO:0030448
Growth of fungi as threadlike, tubular structures that may contain multiple nuclei and may or may not be divided internally by septa, or cross-walls.
1 Q96UX3 (/IMP)
Negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512
Any process that stops, prevents, or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway.
1 O76360 (/IGI)
Larval feeding behavior GO:0030536
Feeding behavior in a larval (immature) organism.
1 O76360 (/IGI)
Regulation of cAMP biosynthetic process GO:0030817
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).
1 P05987 (/IMP)
Positive regulation of cAMP biosynthetic process GO:0030819
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).
1 P05987 (/IDA)
Negative regulation of cGMP biosynthetic process GO:0030827
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cGMP.
1 O76360 (/IMP)
Forebrain development GO:0030900
The process whose specific outcome is the progression of the forebrain over time, from its formation to the mature structure. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions).
1 P0C605 (/IMP)
Culmination involved in sorocarp development GO:0031154
The process whose specific outcome is the progression of the culminant over time, from its formation to the mature structure. Culmination begins with a morphogenetic change of the finger-like or migratory slug giving rise to an organized structure containing a stalk and a sorus. This process is the final stage of sorocarp development.
1 P05987 (/IMP)
Regulation of sorocarp development GO:0031156
Any process that modulates the frequency, rate or extent of sorocarp development. An example of this process is found in Dictyostelium discoideum.
1 P05987 (/IMP)
Regulation of sorocarp stalk cell differentiation GO:0031285
Any process that modulates the frequency, rate or extent of sorocarp stalk cell differentiation. An example of this process is found in Dictyostelium discoideum.
1 P05987 (/IGI)
Sorocarp morphogenesis GO:0031288
The process in which the sorocarp is generated and organized. An example of this process is found in Dictyostelium discoideum.
1 P05987 (/IMP)
Circadian regulation of gene expression GO:0032922
Any process that modulates the frequency, rate or extent of gene expression such that an expression pattern recurs with a regularity of approximately 24 hours.
1 Q61410 (/IMP)
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
1 Q96UX3 (/IMP)
Cellular response to heat GO:0034605
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
1 Q9HEW1 (/IMP)
Filamentous growth of a population of unicellular organisms in response to starvation GO:0036170
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to deprivation of nourishment.
1 Q9HEW1 (/IMP)
Filamentous growth of a population of unicellular organisms in response to biotic stimulus GO:0036180
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a biotic (living) stimulus.
1 Q9HEW1 (/IMP)
Peptidyl-serine autophosphorylation GO:0036289
The phosphorylation by a protein of one or more of its own serine amino acid residues, or a serine residue on an identical protein.
1 Q64595 (/IDA)
Regulation of multicellular organism growth GO:0040014
Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size.
1 O76360 (/IGI)
Negative regulation of multicellular organism growth GO:0040015
Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organism to reach its usual body size.
1 O76360 (/IGI)
Negative regulation of multicellular organism growth GO:0040015
Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organism to reach its usual body size.
1 O76360 (/IMP)
Response to hydrogen peroxide GO:0042542
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
1 O76360 (/IMP)
Positive regulation of circadian rhythm GO:0042753
Any process that activates or increases the frequency, rate or extent of a circadian rhythm behavior.
1 A9LNM8 (/IMP)
Regulation of GTPase activity GO:0043087
Any process that modulates the rate of GTP hydrolysis by a GTPase.
1 Q13976 (/IMP)
Regulation of GTPase activity GO:0043087
Any process that modulates the rate of GTP hydrolysis by a GTPase.
1 P0C605 (/ISO)
Chemotropism GO:0043577
The movement of an organism, or part of an organism, in response to an external chemical gradient, usually toward or away from it.
1 O76360 (/IGI)
Chemotropism GO:0043577
The movement of an organism, or part of an organism, in response to an external chemical gradient, usually toward or away from it.
1 O76360 (/IMP)
Regulation of cAMP-mediated signaling GO:0043949
Any process which modulates the frequency, rate or extent of cAMP-mediated signaling, a series of molecular signals in which a cell uses cyclic AMP to convert an extracellular signal into a response.
1 P05987 (/IMP)
Locomotor rhythm GO:0045475
The rhythm of the locomotor activity of an organism during its 24 hour activity cycle.
1 P81900 (/IMP)
Locomotor rhythm GO:0045475
The rhythm of the locomotor activity of an organism during its 24 hour activity cycle.
1 P81900 (/NAS)
Positive regulation of adenylate cyclase activity GO:0045762
Any process that activates or increases the frequency, rate or extent of adenylate cyclase activity.
1 P07278 (/IGI)
Negative regulation of cell volume GO:0045794
Any process that decreases cell volume.
1 Q61410 (/IGI)
Negative regulation of heart contraction GO:0045822
Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction.
1 A9LNM8 (/IMP)
Regulation of protein kinase activity GO:0045859
Any process that modulates the frequency, rate or extent of protein kinase activity.
1 P05987 (/IMP)
Negative regulation of smooth muscle contraction GO:0045986
Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle contraction.
1 P0C605 (/IMP)
Negative regulation of Ras protein signal transduction GO:0046580
Any process that stops, prevents, or reduces the frequency, rate or extent of Ras protein signal transduction.
1 P07278 (/IDA)
Negative regulation of Ras protein signal transduction GO:0046580
Any process that stops, prevents, or reduces the frequency, rate or extent of Ras protein signal transduction.
1 P07278 (/IMP)
Negative regulation of organ growth GO:0046621
Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism.
1 O76360 (/IMP)
Regulation of oviposition GO:0046662
Any process that modulates the frequency, rate or extent of the deposition of eggs, either fertilized or not, upon a surface or into a medium.
1 O76360 (/IGI)
Regulation of oviposition GO:0046662
Any process that modulates the frequency, rate or extent of the deposition of eggs, either fertilized or not, upon a surface or into a medium.
1 O76360 (/IMP)
Positive regulation of protein export from nucleus GO:0046827
Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm.
1 P36600 (/IMP)
Behavioral response to cocaine GO:0048148
Any process that results in a change in the behavior of an organism as a result of a cocaine stimulus.
1 P81900 (/IMP)
Behavioral response to cocaine GO:0048148
Any process that results in a change in the behavior of an organism as a result of a cocaine stimulus.
1 P81900 (/NAS)
Behavioral response to ethanol GO:0048149
Any process that results in a change in the behavior of an organism as a result of an ethanol stimulus.
1 P81900 (/IMP)
Behavioral response to ethanol GO:0048149
Any process that results in a change in the behavior of an organism as a result of an ethanol stimulus.
1 P81900 (/NAS)
Behavioral response to ethanol GO:0048149
Any process that results in a change in the behavior of an organism as a result of an ethanol stimulus.
1 P81900 (/TAS)
Negative regulation of calcium-mediated signaling GO:0050849
Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-mediated signaling.
1 O76360 (/IMP)
Sensory perception of bitter taste GO:0050913
The series of events required to receive a bitter taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
1 O76360 (/IGI)
Sensory perception of bitter taste GO:0050913
The series of events required to receive a bitter taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
1 O76360 (/IMP)
Positive regulation of chemotaxis GO:0050921
Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.
1 O76360 (/IGI)
Positive regulation of chemotaxis GO:0050921
Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.
1 O76360 (/IMP)
Regulation of nitric-oxide synthase activity GO:0050999
Any process that modulates the activity of the enzyme nitric-oxide synthase.
1 Q13237 (/TAS)
Protein heterooligomerization GO:0051291
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers that are not all identical. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
1 P12368 (/IDA)
Positive regulation of cyclic-nucleotide phosphodiesterase activity GO:0051343
Any process that activates or increases the frequency, rate or extent of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate.
1 O76360 (/IGI)
Negative regulation of meiotic cell cycle GO:0051447
Any process that stops, prevents or reduces the rate or extent of progression through the meiotic cell cycle.
1 P36600 (/IGI)
Negative regulation of nuclear division GO:0051784
Any process that stops, prevents, or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.
1 Q96UX3 (/IMP)
Relaxation of vascular smooth muscle GO:0060087
A negative regulation of smooth muscle contraction resulting in relaxation of vascular smooth muscle. The relaxation is mediated by a decrease in the phosphorylation state of myosin light chain. This can be achieved by removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases leading to a decrease myosin light chain kinase activity, and through calcium-independent pathways leading to a increase in myosin light chain phosphatase activity.
1 P0C605 (/IMP)
Cell growth involved in cardiac muscle cell development GO:0061049
The growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.
1 A9LNM8 (/IMP)
Negative regulation of dauer larval development GO:0061067
Any process that decreases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.
1 O76360 (/IMP)
Response to oxygen levels GO:0070482
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen.
1 O76360 (/IMP)
Cellular hypotonic response GO:0071476
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hypotonic environment, i.e. an environment with a lower concentration of solutes than the organism or cell.
1 Q61410 (/IDA)
Medium-term memory GO:0072375
The memory process that deals with the storage, retrieval and modification of information received at a time ago that is intermediate between that of short and long term memory (30min - 7hrs in Drosophila melanogaster).
1 P30625 (/IMP)
Protein targeting to plasma membrane GO:0072661
The process of directing proteins towards the plasma membrane; usually uses signals contained within the protein.
1 Q64595 (/IMP)
Negative regulation of protein kinase C signaling GO:0090038
Any process that decreases the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.
1 P30625 (/IGI)
Negative regulation of platelet aggregation GO:0090331
Any process that decreases the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.
1 Q13976 (/IMP)
Negative regulation of platelet aggregation GO:0090331
Any process that decreases the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.
1 P0C605 (/ISO)
Protein localization to bud neck GO:0097271
A process in which a protein is transported to, or maintained at, a location within a cellular bud neck.
1 P07278 (/IGI)
Response to antipsychotic drug GO:0097332
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antipsychotic drug stimulus. Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect.
1 P12369 (/IEP)
Ciliary basal body docking GO:0097711
The docking of a cytosolic centriole/basal body to the plasma membrane via the ciliary transition fibers. In some species this may happen via an intermediate step, by first docking to the ciliary vesicle via the ciliary transition fibers. The basal body-ciliary vesicle then relocates to the plasma membrane, followed by the ciliary vesicle fusing with the plasma membrane, effectively attaching the basal body to the plasma membrane.
1 P31323 (/TAS)
Positive regulation of blood vessel diameter GO:0097755
Any process that increases the diameter of blood vessels.
1 A9LNM8 (/IMP)
Negative regulation of oocyte maturation GO:1900194
Any process that stops, prevents or reduces the frequency, rate or extent of oocyte maturation.
1 P30625 (/IMP)
Negative regulation of filamentous growth of a population of unicellular organisms in response to starvation GO:1900435
Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to starvation.
1 Q9HEW1 (/IMP)
Negative regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus GO:1900444
Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to biotic stimulus.
1 Q9HEW1 (/IMP)
Positive regulation of oviposition GO:1901046
Any process that activates or increases the frequency, rate or extent of oviposition.
1 O76360 (/IMP)
Negative regulation of cyclic nucleotide-gated ion channel activity GO:1902160
Any process that stops, prevents or reduces the frequency, rate or extent of cyclic nucleotide-gated ion channel activity.
1 O76360 (/IGI)
Positive regulation of large conductance calcium-activated potassium channel activity GO:1902608
Any process that activates or increases the frequency, rate or extent of large conductance calcium-activated potassium channel activity.
1 A9LNM8 (/IMP)
Regulation of eating behavior GO:1903998
Any process that modulates the frequency, rate or extent of eating behavior.
1 O76360 (/IGI)
Positive regulation of cellular response to alcohol GO:1905959
Any process that activates or increases the frequency, rate or extent of cellular response to alcohol.
1 O76360 (/IGI)
Positive regulation of cellular response to alcohol GO:1905959
Any process that activates or increases the frequency, rate or extent of cellular response to alcohol.
1 O76360 (/IMP)
Process resulting in tolerance to alcohol GO:1990335
A response to alcohol that results in a state of tolerance to alcohol.
1 O76360 (/IMP)
Response to odorant GO:1990834
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an odorant stimulus. An odorant is any substance capable of stimulating the sense of smell.
1 O76360 (/IGI)
Response to odorant GO:1990834
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an odorant stimulus. An odorant is any substance capable of stimulating the sense of smell.
1 O76360 (/IMP)
Regulation of establishment of cell polarity GO:2000114
Any process that modulates the frequency, rate or extent of establishment of cell polarity.
1 P30625 (/IGI)
Regulation of testosterone biosynthetic process GO:2000224
Any process that modulates the frequency, rate or extent of testosterone biosynthetic process.
1 A9LNM8 (/IMP)
Negative regulation of chloride transport GO:2001226
Any process that stops, prevents or reduces the frequency, rate or extent of chloride transport.
1 Q64595 (/IDA)

There are 56 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
12 P07278 (/IDA) P12368 (/IDA) P12369 (/IDA) P13861 (/IDA) P31323 (/IDA) P32023 (/IDA) P36600 (/IDA) P81900 (/IDA) Q03042 (/IDA) Q03043 (/IDA)
(2 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
9 P07278 (/IDA) P0C605 (/IDA) P13861 (/IDA) P31323 (/IDA) P32023 (/IDA) P81900 (/IDA) Q03043 (/IDA) Q13976 (/IDA) Q61410 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
6 A9LNM8 (/IDA) O76360 (/IDA) P30625 (/IDA) P32023 (/IDA) P36600 (/IDA) Q03043 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
6 P00516 (/TAS) P05987 (/TAS) P13861 (/TAS) P31323 (/TAS) Q13237 (/TAS) Q13976 (/TAS)
CAMP-dependent protein kinase complex GO:0005952
An enzyme complex, composed of regulatory and catalytic subunits, that catalyzes protein phosphorylation. Inactive forms of the enzyme have two regulatory chains and two catalytic chains; activation by cAMP produces two active catalytic monomers and a regulatory dimer.
5 P05987 (/IDA) P12368 (/IDA) P12369 (/IDA) P30625 (/IDA) P36600 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
4 O76360 (/IDA) P07278 (/IDA) P36600 (/IDA) Q9HEW1 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
4 O77676 (/ISS) P00516 (/ISS) P0C605 (/ISS) Q9VL34 (/ISS)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
4 A9LNM8 (/IDA) P13861 (/IDA) P30625 (/IDA) Q64595 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 C1PIG4 (/IMP) O76360 (/IMP) P05207 (/IMP)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 P0C605 (/ISO) P12367 (/ISO) P31324 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
3 P0C605 (/ISO) P12367 (/ISO) P31324 (/ISO)
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
2 A9LNM8 (/IDA) P0C605 (/IDA)
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
2 P13861 (/IDA) P31323 (/IDA)
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
2 P12367 (/ISO) P31324 (/ISO)
Germinal vesicle GO:0042585
The enlarged, fluid filled nucleus of a primary oocyte, the development of which is suspended in prophase I of the first meiotic division between embryohood and sexual maturity.
2 C1PIG4 (/IMP) P05207 (/IMP)
Dendritic spine GO:0043197
A small, membranous protrusion from a dendrite that forms a postsynaptic compartment - typically receiving input from a single presynapse. They function as partially isolated biochemical and an electrical compartments. Spine morphology is variable including \thin\, \stubby\, \mushroom\, and \branched\, with a continuum of intermediate morphologies. They typically terminate in a bulb shape, linked to the dendritic shaft by a restriction. Spine remodeling is though to be involved in synaptic plasticity.
2 P12369 (/ISS) P31323 (/ISS)
Dendritic shaft GO:0043198
Cylindric portion of the dendrite, directly stemming from the perikaryon, and carrying the dendritic spines.
2 P12369 (/ISS) P31323 (/ISS)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
2 P12368 (/IDA) P12369 (/IDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
2 P13861 (/IDA) P31323 (/IDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
2 P12367 (/ISO) P31324 (/ISO)
Ciliary base GO:0097546
Area of the cilium (also called flagellum) where the basal body and the axoneme are anchored to the plasma membrane. The ciliary base encompasses the distal part of the basal body, transition fibers and transition zone and is structurally and functionally very distinct from the rest of the cilium. In this area proteins are sorted and filtered before entering the cilium, and many ciliary proteins localize specifically to this area.
2 P13861 (/TAS) P31323 (/TAS)
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
1 P07278 (/IDA)
Acrosomal vesicle GO:0001669
A structure in the head of a spermatozoon that contains acid hydrolases, and is concerned with the breakdown of the outer membrane of the ovum during fertilization. It lies just beneath the plasma membrane and is derived from the lysosome.
1 A9LNM8 (/IDA)
Intracellular GO:0005622
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
1 A2R7J4 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 O76360 (/IMP)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9HEW1 (/IPI)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9HEW1 (/NAS)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 A9LNM8 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 P13861 (/TAS)
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
1 P12369 (/IDA)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
1 Q8I719 (/IDA)
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
1 P05987 (/TAS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 P0C605 (/IMP)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q9VL34 (/ISS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 P13861 (/TAS)
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
1 P13861 (/IDA)
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
1 P12367 (/ISO)
CAMP-dependent protein kinase complex GO:0005952
An enzyme complex, composed of regulatory and catalytic subunits, that catalyzes protein phosphorylation. Inactive forms of the enzyme have two regulatory chains and two catalytic chains; activation by cAMP produces two active catalytic monomers and a regulatory dimer.
1 P05987 (/IC)
CAMP-dependent protein kinase complex GO:0005952
An enzyme complex, composed of regulatory and catalytic subunits, that catalyzes protein phosphorylation. Inactive forms of the enzyme have two regulatory chains and two catalytic chains; activation by cAMP produces two active catalytic monomers and a regulatory dimer.
1 Q7KQK0 (/ISS)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 P12367 (/ISO)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 P13861 (/TAS)
Extrinsic component of membrane GO:0019898
The component of a membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
1 Q8I719 (/IDA)
T-tubule GO:0030315
Invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril. The ends of T-tubules make contact with the sarcoplasmic reticulum membrane.
1 P12368 (/IDA)
Dendrite GO:0030425
A neuron projection that has a short, tapering, often branched, morphology, receives and integrates signals from other neurons or from sensory stimuli, and conducts a nerve impulse towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
1 P12369 (/IDA)
Nucleotide-activated protein kinase complex GO:0031588
A protein complex that possesses nucleotide-dependent protein kinase activity. The nucleotide can be AMP (in S. pombe and human) or ADP (in S. cerevisiae).
1 P13861 (/IDA)
Nucleotide-activated protein kinase complex GO:0031588
A protein complex that possesses nucleotide-dependent protein kinase activity. The nucleotide can be AMP (in S. pombe and human) or ADP (in S. cerevisiae).
1 P12367 (/ISO)
Nuclear membrane GO:0031965
Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
1 Q64595 (/IDA)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
1 P12369 (/IDA)
Dendritic spine GO:0043197
A small, membranous protrusion from a dendrite that forms a postsynaptic compartment - typically receiving input from a single presynapse. They function as partially isolated biochemical and an electrical compartments. Spine morphology is variable including \thin\, \stubby\, \mushroom\, and \branched\, with a continuum of intermediate morphologies. They typically terminate in a bulb shape, linked to the dendritic shaft by a restriction. Spine remodeling is though to be involved in synaptic plasticity.
1 P31324 (/IDA)
Dendritic shaft GO:0043198
Cylindric portion of the dendrite, directly stemming from the perikaryon, and carrying the dendritic spines.
1 P31324 (/IDA)
Protein complex GO:0043234
A stable macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.
1 P12368 (/IDA)
Plasma membrane raft GO:0044853
A membrane raft that is part of the plasma membrane.
1 P13861 (/IDA)
Plasma membrane raft GO:0044853
A membrane raft that is part of the plasma membrane.
1 P12367 (/ISO)
Membrane raft GO:0045121
Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
1 P12369 (/IDA)
Ciliary base GO:0097546
Area of the cilium (also called flagellum) where the basal body and the axoneme are anchored to the plasma membrane. The ciliary base encompasses the distal part of the basal body, transition fibers and transition zone and is structurally and functionally very distinct from the rest of the cilium. In this area proteins are sorted and filtered before entering the cilium, and many ciliary proteins localize specifically to this area.
1 P31324 (/IDA)
Postsynapse GO:0098794
The part of a synapse that is part of the post-synaptic cell.
1 P12369 (/IDA)
CATH-Gene3D is a Global Biodata Core Resource Learn more...