The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Acid Proteases
".
FunFam 23181: Aspartyl protease family protein
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Aspartic-type endopeptidase activity GO:0004190
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile.
|
2 | Q6XBF8 (/IDA) Q9LTW4 (/IDA) |
Aspartic-type endopeptidase activity GO:0004190
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile.
|
2 | G1FTR5 (/IMP) Q9M9A8 (/IMP) |
Aspartic-type endopeptidase activity GO:0004190
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile.
|
2 | Q6XBF8 (/ISS) Q9LZL3 (/ISS) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q9M9A8 (/IPI) |
Peptidase activity GO:0008233
Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
|
1 | Q9LZL3 (/IDA) |
Aspartic-type peptidase activity GO:0070001
Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile.
|
1 | Q9LS40 (/IDA) |
There are 18 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Systemic acquired resistance GO:0009627
The salicylic acid mediated response to a pathogen which confers broad spectrum resistance.
|
2 | Q9LEW3 (/IMP) Q9LS40 (/IMP) |
Response to salt stress GO:0009651
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
|
2 | Q9ZVS4 (/IEP) Q9ZVS5 (/IEP) |
Regulation of programmed cell death GO:0043067
Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.
|
2 | Q6F4N5 (/IMP) Q9SV77 (/IMP) |
Carbohydrate metabolic process GO:0005975
The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule.
|
1 | Q9LTW4 (/IMP) |
Response to water deprivation GO:0009414
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.
|
1 | Q9LS40 (/IMP) |
Response to light stimulus GO:0009416
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.
|
1 | Q9C8C9 (/IEP) |
Pollen development GO:0009555
The process whose specific outcome is the progression of the pollen grain over time, from its formation to the mature structure. The process begins with the meiosis of the microsporocyte to form four haploid microspores. The nucleus of each microspore then divides by mitosis to form a two-celled organism, the pollen grain, that contains a tube cell as well as a smaller generative cell. The pollen grain is surrounded by an elaborate cell wall. In some species, the generative cell immediately divides again to give a pair of sperm cells. In most flowering plants, however this division takes place later, in the tube that develops when a pollen grain germinates.
|
1 | Q9SV77 (/IMP) |
Systemic acquired resistance GO:0009627
The salicylic acid mediated response to a pathogen which confers broad spectrum resistance.
|
1 | O04496 (/IEP) |
Response to abscisic acid GO:0009737
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.
|
1 | Q9LS40 (/IMP) |
Chloroplast-nucleus signaling pathway GO:0010019
The process in which a molecular signal is transduced between the chloroplast and nucleus, such that expression of nuclear encoding photosynthetic proteins is coupled with chloroplast biogenesis.
|
1 | Q9LTW4 (/IMP) |
Regulation of hydrogen peroxide metabolic process GO:0010310
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide.
|
1 | Q6XBF8 (/IDA) |
Regulation of hydrogen peroxide metabolic process GO:0010310
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide.
|
1 | Q6XBF8 (/IMP) |
Regulation of salicylic acid metabolic process GO:0010337
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving salicylic acid.
|
1 | Q6XBF8 (/IMP) |
Programmed cell death GO:0012501
A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell.
|
1 | Q9LZL3 (/IMP) |
Response to L-ascorbic acid GO:0033591
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-ascorbic acid (vitamin C) stimulus.
|
1 | Q9C8C9 (/IEP) |
Defense response to bacterium GO:0042742
Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
|
1 | Q6XBF8 (/IMP) |
Defense response to fungus GO:0050832
Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.
|
1 | Q9M9A8 (/IMP) |
Response to karrikin GO:0080167
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a karrikin stimulus. Karrikins are signaling molecules in smoke from burning vegetation that trigger seed germination for many angiosperms (flowering plants).
|
1 | Q9LNJ3 (/IEP) |
There are 14 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Plant-type cell wall GO:0009505
A more or less rigid stucture lying outside the cell membrane of a cell and composed of cellulose and pectin and other organic and inorganic substances.
|
11 |
F4K5B9 (/IDA)
O04496 (/IDA)
Q940R4 (/IDA)
Q9C6Y5 (/IDA)
Q9FPD6 (/IDA)
Q9LNJ3 (/IDA)
Q9M2U7 (/IDA)
Q9M356 (/IDA)
Q9SVD1 (/IDA)
Q9ZVS4 (/IDA)
(1 more) |
Anchored component of membrane GO:0031225
The component of a membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
|
10 | B3LF45 (/TAS) F4IAD5 (/TAS) F4J3C0 (/TAS) Q4V3D2 (/TAS) Q84WU7 (/TAS) Q8VYV9 (/TAS) Q9FPD6 (/TAS) Q9LX20 (/TAS) Q9M8R6 (/TAS) Q9S9K4 (/TAS) |
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
|
6 | F4K5B9 (/IDA) O04496 (/IDA) Q9M2U7 (/IDA) Q9SVD1 (/IDA) Q9ZVS4 (/IDA) Q9ZVS5 (/IDA) |
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
|
5 | F4K4L3 (/IDA) Q9C6Y5 (/IDA) Q9C8C9 (/IDA) Q9ZVS4 (/IDA) Q9ZVS5 (/IDA) |
Apoplast GO:0048046
The cell membranes and intracellular regions in a plant are connected through plasmodesmata, and plants may be described as having two major compartments: the living symplast and the non-living apoplast. The apoplast is external to the plasma membrane and includes cell walls, intercellular spaces and the lumen of dead structures such as xylem vessels. Water and solutes pass freely through it.
|
5 | O04496 (/IDA) Q6XBF8 (/IDA) Q8RX60 (/IDA) Q9LEW3 (/IDA) Q9M2U7 (/IDA) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
4 | Q9M8R6 (/IDA) Q9S9K4 (/IDA) Q9ZVS4 (/IDA) Q9ZVS5 (/IDA) |
Plasmodesma GO:0009506
A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.
|
3 | Q9M356 (/IDA) Q9M8R6 (/IDA) Q9ZVS4 (/IDA) |
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
3 | Q9LNJ3 (/IDA) Q9SVD1 (/IDA) Q9ZVS4 (/IDA) |
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
2 | Q9LS40 (/IDA) Q9LZL3 (/IDA) |
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
|
2 | Q9LTW4 (/IDA) Q9M2U7 (/IDA) |
Anchored component of plasma membrane GO:0046658
The component of the plasma membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group, that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
|
2 | Q9LX20 (/IDA) Q9S9K4 (/IDA) |
Endosome GO:0005768
A vacuole to which materials ingested by endocytosis are delivered.
|
1 | F4K4L3 (/IDA) |
Trans-Golgi network GO:0005802
The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination.
|
1 | F4K4L3 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q3E9C8 (/IDA) |