The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Acid Proteases
".
FunFam 23002: Cathepsin D (A01 family)
There are 3 EC terms in this cluster
Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
EC Term | Annotations | Evidence |
---|---|---|
Cathepsin D.
[EC: 3.4.23.5]
Specificity similar to, but narrower than, that of pepsin A. Does not cleave the 4-Gln-|-His-5 bond in B chain of insulin.
|
15 |
A0A0S3G4L0
B7QBB2
G3I4W7
O57477
P00795
P07339
P18242
P24268
P80209
P87370 (5 more...) |
Renin.
[EC: 3.4.23.15]
Cleavage of Leu-|-Xaa bond in angiotensinogen to generate angiotensin I.
|
11 |
P00796
P00797
P06281
P08424
P52115
P60016
Q6DLS0
Q6DLW5
Q6DYE7
Q7M3D2 (1 more...) |
Cathepsin E.
[EC: 3.4.23.34]
Similar to cathepsin D, but slightly broader specificity.
|
10 | A0A1L8H7D5 B7ZQ61 P14091 P16228 P25796 P43159 P70269 Q800A0 Q805F2 Q805F3 |