The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Acid Proteases
".
FunFam 22817: Beta-site APP-cleaving enzyme 1
There are 2 EC terms in this cluster
Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
EC Term | Annotations | Evidence |
---|---|---|
Memapsin 1.
[EC: 3.4.23.45]
Broad endopeptidase specificity. Cleaves Glu-Val-Asn-Leu-|-Asp-Ala-Glu- Phe in the Swedish variant of Alzheimer's amyloid precursor protein.
|
6 | A0A061I5J9 A0A061IC94 B3KNE8 Q6IE75 Q9JL18 Q9Y5Z0 |
Memapsin 2.
[EC: 3.4.23.46]
Broad endopeptidase specificity. Cleaves Glu-Val-Asn-Leu-|-Asp-Ala-Glu- Phe in the Swedish variant of Alzheimer's amyloid precursor protein.
|
6 | P56817 P56818 P56819 Q1KLR6 Q2HJ40 V6F9A9 |