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CATH Superfamily 2.40.10.10

Trypsin-like serine proteases

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Trypsin-like serine proteases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 47764: Putative secreted serine protease

There are 5 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Streptogrisin B. [EC: 3.4.21.81]
Hydrolysis of proteins with trypsin-like specificity.
  • Belongs to peptidase family S1E.
 72 A0A089X8V9 A0A089X8V9 A0A0K2APS6 A0A0K2APS6 A0A0M0EBL7 A0A0M0EBL7 A0A0N0MLR9 A0A0N0MLR9 A0A0N1FTU9 A0A0N1FTU9
(62 more...)
Alpha-lytic endopeptidase. [EC: 3.4.21.12]
Preferential cleavage: Ala-|-Xaa, Val-|-Xaa in bacterial cell walls, elastin and other proteins.
  • Belongs to peptidase family S1E.
 26 A0A0S2FDF4 A0A0S2FDF4 A0A0S2FSK2 A0A0S2FSK2 A0A0S2G4H9 A0A0S2G4H9 A0A0U5LV16 A0A0U5LV16 A0A1B9ESM4 A0A1B9ESM4
(16 more...)
Streptogrisin A. [EC: 3.4.21.80]
Hydrolysis of proteins with specificity similar to chymotrypsin.
  • Not inhibited by Tos-Phe-CH(2)Cl or ovomucoid.
  • Belongs to peptidase family S1E.
 22 A0A060N3B8 A0A060N3B8 A0A0N1NH30 A0A0N1NH30 A0A124C103 A0A124C103 A0A1A9D3M9 A0A1A9D3M9 A0A1B9EXT1 A0A1B9EXT1
(12 more...)
Glutamyl endopeptidase II. [EC: 3.4.21.82]
Preferential cleavage: -Glu-|-Xaa- >> -Asp-|-Xaa-. Preference for Pro or Leu at P2 and Phe at P3. Cleavage of -Glu-|-Asp- and -Glu-|-Pro- bonds is slow.
  • Inhibited by (18-Leu->Glu) modified turkey ovomucoid third domain.
  • Belongs to peptidase family S1E.
 10 A0A0D6VLE1 A0A0D6VLE1 A0A1A9CDN6 A0A1A9CDN6 A0A1C4S164 A0A1C4S164 G0Q496 G0Q496 Q07006 Q07006
Catechol 1,2-dioxygenase. [EC: 1.13.11.1]
Catechol + O(2) = cis,cis-muconate.
  • Involved in the metabolism of nitro-aromatic compounds by a strain of Pseudomonas putida.
  • Formerly EC 1.13.1.1 and EC 1.99.2.2.
 2 A0A1M4DWA2 A0A1M4DWA2
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