The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 23476: Na(+)/H(+) exchange regulatory cofactor NHE-RF3
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
4 | Q5T2W1 (/IPI) Q865P3 (/IPI) Q9JIL4 (/IPI) Q9JJ40 (/IPI) |
|
Scavenger receptor binding GO:0005124
Interacting selectively and non-covalently with scavenger receptors, a family of proteins that are expressed on myeloid cells and are involved in the uptake of effete cellular components and foreign particles.
|
1 | Q9JJ40 (/IDA) |
|
Transporter activity GO:0005215
Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells.
|
1 | Q5T2W1 (/TAS) |
|
PDZ domain binding GO:0030165
Interacting selectively and non-covalently with a PDZ domain of a protein, a domain found in diverse signaling proteins.
|
1 | Q5T2W1 (/IPI) |
|
PDZ domain binding GO:0030165
Interacting selectively and non-covalently with a PDZ domain of a protein, a domain found in diverse signaling proteins.
|
1 | Q9JIL4 (/ISO) |
|
Protein complex binding GO:0032403
Interacting selectively and non-covalently with any protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q9JJ40 (/IPI) |
There are 15 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Regulation of anion transport GO:0044070
Any process that modulates the frequency, rate or extent of the directed movement of anions, atoms or small molecules with a net negative charge into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
5 | Q3T0X8 (/ISS) Q5RCF7 (/ISS) Q5T2W1 (/ISS) Q865P3 (/ISS) Q9JJ40 (/ISS) |
|
Positive regulation of protein targeting to membrane GO:0090314
Any process that increases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.
|
5 | Q3T0X8 (/ISS) Q5RCF7 (/ISS) Q5T2W1 (/ISS) Q865P3 (/ISS) Q9JJ40 (/ISS) |
|
Transport GO:0006810
The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter, pore or motor protein.
|
1 | Q5T2W1 (/IDA) |
|
Transport GO:0006810
The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter, pore or motor protein.
|
1 | Q9JIL4 (/ISO) |
|
Cell proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
|
1 | Q5T2W1 (/TAS) |
|
Carnitine transport GO:0015879
The directed movement of carnitine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carnitine is a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.
|
1 | Q5T2W1 (/IDA) |
|
Carnitine transport GO:0015879
The directed movement of carnitine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carnitine is a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.
|
1 | Q9JIL4 (/ISO) |
|
Drug transport GO:0015893
The directed movement of a drug, a substance used in the diagnosis, treatment or prevention of a disease, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | Q5T2W1 (/NAS) |
|
Cholesterol transport GO:0030301
The directed movement of cholesterol, cholest-5-en-3-beta-ol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | Q9JJ40 (/NAS) |
|
Positive regulation of ion transmembrane transport GO:0034767
Any process that activates or increases the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.
|
1 | Q5T2W1 (/IDA) |
|
Positive regulation of ion transmembrane transport GO:0034767
Any process that activates or increases the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.
|
1 | Q9JIL4 (/ISO) |
|
Regulation of anion transport GO:0044070
Any process that modulates the frequency, rate or extent of the directed movement of anions, atoms or small molecules with a net negative charge into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | Q9JIL4 (/IMP) |
|
Intracellular transport GO:0046907
The directed movement of substances within a cell.
|
1 | Q9JJ40 (/NAS) |
|
Establishment of protein localization to plasma membrane GO:0090002
The directed movement of a protein to a specific location in the plasma membrane.
|
1 | Q9JIL4 (/IMP) |
|
Positive regulation of protein targeting to membrane GO:0090314
Any process that increases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.
|
1 | Q9JIL4 (/IMP) |
There are 9 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
5 | Q3T0X8 (/ISS) Q5RCF7 (/ISS) Q5T2W1 (/ISS) Q865P3 (/ISS) Q9JJ40 (/ISS) |
|
Brush border membrane GO:0031526
The portion of the plasma membrane surrounding the brush border.
|
5 | Q3T0X8 (/ISS) Q5RCF7 (/ISS) Q5T2W1 (/ISS) Q865P3 (/ISS) Q9JJ40 (/ISS) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q9JIL4 (/IDA) |
|
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
|
1 | Q9JJ40 (/IDA) |
|
Brush border membrane GO:0031526
The portion of the plasma membrane surrounding the brush border.
|
1 | Q9JIL4 (/IDA) |
|
Microvillus membrane GO:0031528
The portion of the plasma membrane surrounding a microvillus.
|
1 | Q9JJ40 (/IDA) |
|
Membrane raft GO:0045121
Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
|
1 | Q9JJ40 (/IDA) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
1 | Q5T2W1 (/IDA) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
1 | Q9JIL4 (/ISO) |
