The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
SH3 Domains
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 714: Polychaetoid, isoform G

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Guanylate kinase activity GO:0004385
Catalysis of the reaction: ATP + GMP = ADP + GDP.
9 A0A0B4K6C7 (/ISS) A0A0B4K6Y7 (/ISS) A8JQV7 (/ISS) A8JQV8 (/ISS) B7Z0U1 (/ISS) Q8INQ0 (/ISS) Q9VHK1 (/ISS) Q9VHK3 (/ISS) Q9VHK4 (/ISS)
Ubiquitin protein ligase binding GO:0031625
Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.
9 A0A0B4K6C7 (/IPI) A0A0B4K6Y7 (/IPI) A8JQV7 (/IPI) A8JQV8 (/IPI) B7Z0U1 (/IPI) Q8INQ0 (/IPI) Q9VHK1 (/IPI) Q9VHK3 (/IPI) Q9VHK4 (/IPI)
WW domain binding GO:0050699
Interacting selectively and non-covalently with a WW domain of a protein, a small module composed of 40 amino acids and plays a role in mediating protein-protein interactions via proline-rich regions.
9 A0A0B4K6C7 (/IPI) A0A0B4K6Y7 (/IPI) A8JQV7 (/IPI) A8JQV8 (/IPI) B7Z0U1 (/IPI) Q8INQ0 (/IPI) Q9VHK1 (/IPI) Q9VHK3 (/IPI) Q9VHK4 (/IPI)
Cell adhesion molecule binding GO:0050839
Interacting selectively and non-covalently with a cell adhesion molecule.
9 A0A0B4K6C7 (/IPI) A0A0B4K6Y7 (/IPI) A8JQV7 (/IPI) A8JQV8 (/IPI) B7Z0U1 (/IPI) Q8INQ0 (/IPI) Q9VHK1 (/IPI) Q9VHK3 (/IPI) Q9VHK4 (/IPI)

There are 24 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Compound eye morphogenesis GO:0001745
The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster.
9 A0A0B4K6C7 (/IMP) A0A0B4K6Y7 (/IMP) A8JQV7 (/IMP) A8JQV8 (/IMP) B7Z0U1 (/IMP) Q8INQ0 (/IMP) Q9VHK1 (/IMP) Q9VHK3 (/IMP) Q9VHK4 (/IMP)
Establishment or maintenance of cell polarity GO:0007163
Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns.
9 A0A0B4K6C7 (/NAS) A0A0B4K6Y7 (/NAS) A8JQV7 (/NAS) A8JQV8 (/NAS) B7Z0U1 (/NAS) Q8INQ0 (/NAS) Q9VHK1 (/NAS) Q9VHK3 (/NAS) Q9VHK4 (/NAS)
Notch signaling pathway GO:0007219
A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Notch on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
9 A0A0B4K6C7 (/IMP) A0A0B4K6Y7 (/IMP) A8JQV7 (/IMP) A8JQV8 (/IMP) B7Z0U1 (/IMP) Q8INQ0 (/IMP) Q9VHK1 (/IMP) Q9VHK3 (/IMP) Q9VHK4 (/IMP)
JNK cascade GO:0007254
An intracellular protein kinase cascade containing at least a JNK (a MAPK), a JNKK (a MAPKK) and a JUN3K (a MAP3K). The cascade can also contain two additional tiers: the upstream MAP4K and the downstream MAP Kinase-activated kinase (MAPKAPK). The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell.
9 A0A0B4K6C7 (/NAS) A0A0B4K6Y7 (/NAS) A8JQV7 (/NAS) A8JQV8 (/NAS) B7Z0U1 (/NAS) Q8INQ0 (/NAS) Q9VHK1 (/NAS) Q9VHK3 (/NAS) Q9VHK4 (/NAS)
Dorsal closure GO:0007391
The process during Drosophila embryogenesis whereby the ectodermal cells of the lateral epithelium stretch in a coordinated fashion to internalize the amnioserosa cells and close the embryo dorsally.
9 A0A0B4K6C7 (/IMP) A0A0B4K6Y7 (/IMP) A8JQV7 (/IMP) A8JQV8 (/IMP) B7Z0U1 (/IMP) Q8INQ0 (/IMP) Q9VHK1 (/IMP) Q9VHK3 (/IMP) Q9VHK4 (/IMP)
Dorsal closure GO:0007391
The process during Drosophila embryogenesis whereby the ectodermal cells of the lateral epithelium stretch in a coordinated fashion to internalize the amnioserosa cells and close the embryo dorsally.
9 A0A0B4K6C7 (/NAS) A0A0B4K6Y7 (/NAS) A8JQV7 (/NAS) A8JQV8 (/NAS) B7Z0U1 (/NAS) Q8INQ0 (/NAS) Q9VHK1 (/NAS) Q9VHK3 (/NAS) Q9VHK4 (/NAS)
Dorsal closure GO:0007391
The process during Drosophila embryogenesis whereby the ectodermal cells of the lateral epithelium stretch in a coordinated fashion to internalize the amnioserosa cells and close the embryo dorsally.
9 A0A0B4K6C7 (/TAS) A0A0B4K6Y7 (/TAS) A8JQV7 (/TAS) A8JQV8 (/TAS) B7Z0U1 (/TAS) Q8INQ0 (/TAS) Q9VHK1 (/TAS) Q9VHK3 (/TAS) Q9VHK4 (/TAS)
Open tracheal system development GO:0007424
The process whose specific outcome is the progression of an open tracheal system over time, from its formation to the mature structure. An open tracheal system is a respiratory system, a branched network of epithelial tubes that supplies oxygen to target tissues via spiracles. An example of this is found in Drosophila melanogaster.
9 A0A0B4K6C7 (/IMP) A0A0B4K6Y7 (/IMP) A8JQV7 (/IMP) A8JQV8 (/IMP) B7Z0U1 (/IMP) Q8INQ0 (/IMP) Q9VHK1 (/IMP) Q9VHK3 (/IMP) Q9VHK4 (/IMP)
Head involution GO:0008258
Movement of the anterior ectoderm to the interior of the embryo.
9 A0A0B4K6C7 (/IMP) A0A0B4K6Y7 (/IMP) A8JQV7 (/IMP) A8JQV8 (/IMP) B7Z0U1 (/IMP) Q8INQ0 (/IMP) Q9VHK1 (/IMP) Q9VHK3 (/IMP) Q9VHK4 (/IMP)
Single organismal cell-cell adhesion GO:0016337
The attachment of one cell to another cell via adhesion molecules, where both cells are part of the same organism.
9 A0A0B4K6C7 (/IMP) A0A0B4K6Y7 (/IMP) A8JQV7 (/IMP) A8JQV8 (/IMP) B7Z0U1 (/IMP) Q8INQ0 (/IMP) Q9VHK1 (/IMP) Q9VHK3 (/IMP) Q9VHK4 (/IMP)
Regulation of embryonic cell shape GO:0016476
Any process that modulates the surface configuration of an embryonic cell.
9 A0A0B4K6C7 (/IMP) A0A0B4K6Y7 (/IMP) A8JQV7 (/IMP) A8JQV8 (/IMP) B7Z0U1 (/IMP) Q8INQ0 (/IMP) Q9VHK1 (/IMP) Q9VHK3 (/IMP) Q9VHK4 (/IMP)
Chaeta development GO:0022416
The process whose specific outcome is the progression of a chaeta over time, from its formation to the mature structure. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell.
9 A0A0B4K6C7 (/IMP) A0A0B4K6Y7 (/IMP) A8JQV7 (/IMP) A8JQV8 (/IMP) B7Z0U1 (/IMP) Q8INQ0 (/IMP) Q9VHK1 (/IMP) Q9VHK3 (/IMP) Q9VHK4 (/IMP)
Regulation of cell adhesion GO:0030155
Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix.
9 A0A0B4K6C7 (/IGI) A0A0B4K6Y7 (/IGI) A8JQV7 (/IGI) A8JQV8 (/IGI) B7Z0U1 (/IGI) Q8INQ0 (/IGI) Q9VHK1 (/IGI) Q9VHK3 (/IGI) Q9VHK4 (/IGI)
Regulation of cell adhesion GO:0030155
Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix.
9 A0A0B4K6C7 (/IMP) A0A0B4K6Y7 (/IMP) A8JQV7 (/IMP) A8JQV8 (/IMP) B7Z0U1 (/IMP) Q8INQ0 (/IMP) Q9VHK1 (/IMP) Q9VHK3 (/IMP) Q9VHK4 (/IMP)
Branch fusion, open tracheal system GO:0035147
Fusing of specific tracheal branches in an open tracheal system to branches from neighboring hemisegments to form a continuous tracheal network. Branch fusion is mediated by individual cells at the tip of each branch, which contact a similar cell and undergo a coordinated series of morphogenetic events that create a bicellular fusion joint.
9 A0A0B4K6C7 (/IMP) A0A0B4K6Y7 (/IMP) A8JQV7 (/IMP) A8JQV8 (/IMP) B7Z0U1 (/IMP) Q8INQ0 (/IMP) Q9VHK1 (/IMP) Q9VHK3 (/IMP) Q9VHK4 (/IMP)
Fusion cell fate specification GO:0035156
The process in which a cell becomes capable of differentiating autonomously into a fusion cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. Fusion cells allow the interconnection of adjacent tracheal metameres during tracheal tube fusion.
9 A0A0B4K6C7 (/IMP) A0A0B4K6Y7 (/IMP) A8JQV7 (/IMP) A8JQV8 (/IMP) B7Z0U1 (/IMP) Q8INQ0 (/IMP) Q9VHK1 (/IMP) Q9VHK3 (/IMP) Q9VHK4 (/IMP)
Wing disc development GO:0035220
Progression of the wing disc over time, from its initial formation through to its metamorphosis to form adult structures including the wing hinge, wing blade and pleura.
9 A0A0B4K6C7 (/IMP) A0A0B4K6Y7 (/IMP) A8JQV7 (/IMP) A8JQV8 (/IMP) B7Z0U1 (/IMP) Q8INQ0 (/IMP) Q9VHK1 (/IMP) Q9VHK3 (/IMP) Q9VHK4 (/IMP)
Nephrocyte diaphragm assembly GO:0036059
The aggregation, arrangement and bonding together of a set of components to form a nephrocyte diaphragm, a specialized cell-cell junction found between nephrocytes of the insect kidney.
9 A0A0B4K6C7 (/IMP) A0A0B4K6Y7 (/IMP) A8JQV7 (/IMP) A8JQV8 (/IMP) B7Z0U1 (/IMP) Q8INQ0 (/IMP) Q9VHK1 (/IMP) Q9VHK3 (/IMP) Q9VHK4 (/IMP)
Apical protein localization GO:0045176
Any process in which a protein is transported to, or maintained in, apical regions of the cell.
9 A0A0B4K6C7 (/IMP) A0A0B4K6Y7 (/IMP) A8JQV7 (/IMP) A8JQV8 (/IMP) B7Z0U1 (/IMP) Q8INQ0 (/IMP) Q9VHK1 (/IMP) Q9VHK3 (/IMP) Q9VHK4 (/IMP)
Regulation of JNK cascade GO:0046328
Any process that modulates the frequency, rate or extent of signal transduction mediated by the JNK cascade.
9 A0A0B4K6C7 (/NAS) A0A0B4K6Y7 (/NAS) A8JQV7 (/NAS) A8JQV8 (/NAS) B7Z0U1 (/NAS) Q8INQ0 (/NAS) Q9VHK1 (/NAS) Q9VHK3 (/NAS) Q9VHK4 (/NAS)
Lateral inhibition GO:0046331
Signaling between cells of equivalent developmental potential that results in these cells adopting different developmental fates. An example is the suppression by cells with a particular fate of the adoption of the same fate by surrounding cells.
9 A0A0B4K6C7 (/IMP) A0A0B4K6Y7 (/IMP) A8JQV7 (/IMP) A8JQV8 (/IMP) B7Z0U1 (/IMP) Q8INQ0 (/IMP) Q9VHK1 (/IMP) Q9VHK3 (/IMP) Q9VHK4 (/IMP)
Neuron projection morphogenesis GO:0048812
The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites.
9 A0A0B4K6C7 (/IMP) A0A0B4K6Y7 (/IMP) A8JQV7 (/IMP) A8JQV8 (/IMP) B7Z0U1 (/IMP) Q8INQ0 (/IMP) Q9VHK1 (/IMP) Q9VHK3 (/IMP) Q9VHK4 (/IMP)
Trachea morphogenesis GO:0060439
The process in which a trachea is generated and organized. The trachea is the portion of the airway that attaches to the bronchi as it branches.
9 A0A0B4K6C7 (/IMP) A0A0B4K6Y7 (/IMP) A8JQV7 (/IMP) A8JQV8 (/IMP) B7Z0U1 (/IMP) Q8INQ0 (/IMP) Q9VHK1 (/IMP) Q9VHK3 (/IMP) Q9VHK4 (/IMP)
Protein localization to cell cortex GO:0072697
A process in which a protein is transported to, or maintained in, the cell cortex.
9 A0A0B4K6C7 (/IDA) A0A0B4K6Y7 (/IDA) A8JQV7 (/IDA) A8JQV8 (/IDA) B7Z0U1 (/IDA) Q8INQ0 (/IDA) Q9VHK1 (/IDA) Q9VHK3 (/IDA) Q9VHK4 (/IDA)

There are 10 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
9 A0A0B4K6C7 (/IDA) A0A0B4K6Y7 (/IDA) A8JQV7 (/IDA) A8JQV8 (/IDA) B7Z0U1 (/IDA) Q8INQ0 (/IDA) Q9VHK1 (/IDA) Q9VHK3 (/IDA) Q9VHK4 (/IDA)
Adherens junction GO:0005912
A cell junction at which anchoring proteins (cadherins or integrins) extend through the plasma membrane and are attached to actin filaments.
9 A0A0B4K6C7 (/IDA) A0A0B4K6Y7 (/IDA) A8JQV7 (/IDA) A8JQV8 (/IDA) B7Z0U1 (/IDA) Q8INQ0 (/IDA) Q9VHK1 (/IDA) Q9VHK3 (/IDA) Q9VHK4 (/IDA)
Adherens junction GO:0005912
A cell junction at which anchoring proteins (cadherins or integrins) extend through the plasma membrane and are attached to actin filaments.
9 A0A0B4K6C7 (/NAS) A0A0B4K6Y7 (/NAS) A8JQV7 (/NAS) A8JQV8 (/NAS) B7Z0U1 (/NAS) Q8INQ0 (/NAS) Q9VHK1 (/NAS) Q9VHK3 (/NAS) Q9VHK4 (/NAS)
Adherens junction GO:0005912
A cell junction at which anchoring proteins (cadherins or integrins) extend through the plasma membrane and are attached to actin filaments.
9 A0A0B4K6C7 (/TAS) A0A0B4K6Y7 (/TAS) A8JQV7 (/TAS) A8JQV8 (/TAS) B7Z0U1 (/TAS) Q8INQ0 (/TAS) Q9VHK1 (/TAS) Q9VHK3 (/TAS) Q9VHK4 (/TAS)
Cell-cell adherens junction GO:0005913
An adherens junction which connects a cell to another cell.
9 A0A0B4K6C7 (/IDA) A0A0B4K6Y7 (/IDA) A8JQV7 (/IDA) A8JQV8 (/IDA) B7Z0U1 (/IDA) Q8INQ0 (/IDA) Q9VHK1 (/IDA) Q9VHK3 (/IDA) Q9VHK4 (/IDA)
Nephrocyte diaphragm GO:0005917
A specialized cell-cell junction found between nephrocytes of the insect kidney, which is adapted for filtration of hemolymph. The insect nephrocyte is anatomically and functionally similar to the glomerular podocyte of vertebrates.
9 A0A0B4K6C7 (/IDA) A0A0B4K6Y7 (/IDA) A8JQV7 (/IDA) A8JQV8 (/IDA) B7Z0U1 (/IDA) Q8INQ0 (/IDA) Q9VHK1 (/IDA) Q9VHK3 (/IDA) Q9VHK4 (/IDA)
Cell cortex GO:0005938
The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
9 A0A0B4K6C7 (/IDA) A0A0B4K6Y7 (/IDA) A8JQV7 (/IDA) A8JQV8 (/IDA) B7Z0U1 (/IDA) Q8INQ0 (/IDA) Q9VHK1 (/IDA) Q9VHK3 (/IDA) Q9VHK4 (/IDA)
Basolateral plasma membrane GO:0016323
The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
9 A0A0B4K6C7 (/IDA) A0A0B4K6Y7 (/IDA) A8JQV7 (/IDA) A8JQV8 (/IDA) B7Z0U1 (/IDA) Q8INQ0 (/IDA) Q9VHK1 (/IDA) Q9VHK3 (/IDA) Q9VHK4 (/IDA)
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
9 A0A0B4K6C7 (/IDA) A0A0B4K6Y7 (/IDA) A8JQV7 (/IDA) A8JQV8 (/IDA) B7Z0U1 (/IDA) Q8INQ0 (/IDA) Q9VHK1 (/IDA) Q9VHK3 (/IDA) Q9VHK4 (/IDA)
Apical part of cell GO:0045177
The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.
9 A0A0B4K6C7 (/IDA) A0A0B4K6Y7 (/IDA) A8JQV7 (/IDA) A8JQV8 (/IDA) B7Z0U1 (/IDA) Q8INQ0 (/IDA) Q9VHK1 (/IDA) Q9VHK3 (/IDA) Q9VHK4 (/IDA)